Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain (Q35097959)

6 August 2017

title

Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain (English)

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6 August 2017

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Bryant M Schultz

1

1 reference

6 August 2017

Gwendolyn A Gallicio

2

1 reference

6 August 2017

Matteo Cesaroni

3

1 reference

6 August 2017

Lena N Lupey

4

1 reference

6 August 2017

Nora Engel

5

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6 August 2017

language of work or name

English

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publication date

24 December 2014

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6 August 2017

published in

Nucleic Acids Research

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6 August 2017

volume

43

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6 August 2017

issue

2

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6 August 2017

page(s)

745-759

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart

9 July 2018

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MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure

9 July 2018

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9 July 2018

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Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.

9 July 2018

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Enhancer-driven chromatin interactions during development promote escape from silencing by a long non-coding RNA.

9 July 2018

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Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells

9 July 2018

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9 July 2018

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9 July 2018

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Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart.

9 July 2018

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Long non-coding RNAs and enhancers

9 July 2018

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Chromatin remodelling complex dosage modulates transcription factor function in heart development

9 July 2018

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9 July 2018

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Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1

9 July 2018

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Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

9 July 2018

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ChIP-seq accurately predicts tissue-specific activity of enhancers

9 July 2018

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Transcription is required for establishment of germline methylation marks at imprinted genes

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Shadow enhancers as a source of evolutionary novelty

9 July 2018

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Two distinct mechanisms of silencing by the KvDMR1 imprinting control region

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

VISTA Enhancer Browser--a database of tissue-specific human enhancers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Making or breaking the heart: from lineage determination to morphogenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

An antisense RNA regulates the bidirectional silencing property of the Kcnq1 imprinting control region

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

rVISTA 2.0: evolutionary analysis of transcription factor binding sites

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Genomic imprinting: intricacies of epigenetic regulation in clusters.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Disruption of Imprinted Gene Methylation and Expression in Cloned Preimplantation Stage Mouse Embryos1

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Tbx5 is required for forelimb bud formation and continued outgrowth

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

A differentially methylated imprinting control region within the Kcnq1 locus harbors a methylation-sensitive chromatin insulator

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

p57Kip2 expression is enhanced during mid-cardiac murine development and is restricted to trabecular myocardium

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Antisense noncoding RNA promoter regulates the timing of de novo methylation of an imprinting control region

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

The three 'C' s of chromosome conformation capture: controls, controls, controls.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Methylation at mouse Cdkn1c is acquired during postimplantation development and functions to maintain imprinted expression.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Selective loss of imprinting in the placenta following preimplantation development in culture

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

A differentially methylated region within the gene Kcnq1 functions as an imprinted promoter and silencer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Imprinting of mouse Kvlqt1 is developmentally regulated.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333379

Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25539921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25539921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bidirectional silencing and DNA methylation-sensitive methylation-spreading properties of the Kcnq1 imprinting control region map to the same regions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25539921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKU1324

1 reference

6 August 2017

1 reference

6 August 2017

1 reference