DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair (Q35097944)

25539916

6 August 2017

title

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair (English)

1 reference

6 August 2017

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25539916 AND SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Ismail Abdou

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25539916 AND SRC:MED&resulttype=core&format=json

12 June 2020

Guy G Poirier

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25539916 AND SRC:MED&resulttype=core&format=json

12 June 2020

Michael Weinfeld

series ordinal

4

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12 June 2020

language of work or name

English

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publication date

24 December 2014

1 reference

25539916

6 August 2017

published in

Nucleic Acids Research

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12 June 2020

volume

43

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issue

2

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12 June 2020

page(s)

875-892

1 reference

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Creative Commons Attribution-NonCommercial 4.0 International

12 June 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4333375/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

9 July 2018

1 reference

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The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites

9 July 2018

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Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair

9 July 2018

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XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

9 July 2018

1 reference

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DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

9 July 2018

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Disconnecting XRCC1 and DNA ligase III

9 July 2018

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DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin

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Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair

9 July 2018

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The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger

9 July 2018

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Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells

9 July 2018

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Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate

9 July 2018

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9 July 2018

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9 July 2018

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Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells

9 July 2018

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Single-strand break repair and genetic disease

9 July 2018

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PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

9 July 2018

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Two DNA-binding and nick recognition modules in human DNA ligase III

9 July 2018

1 reference

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XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks

9 July 2018

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PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

9 July 2018

1 reference

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Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells

9 July 2018

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9 July 2018

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Repair of topoisomerase I-mediated DNA damage

9 July 2018

1 reference

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Differential recruitment of DNA Ligase I and III to DNA repair sites

9 July 2018

1 reference

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The role of poly(ADP-ribose) in the DNA damage signaling network

9 July 2018

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Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.

9 July 2018

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Sensing DNA damage by PARP-like fingers

9 July 2018

1 reference

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A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

9 July 2018

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9 July 2018

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Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1.

9 July 2018

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The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining

9 July 2018

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DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.

9 July 2018

1 reference

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Role of a BRCT domain in the interaction of DNA ligase III-alpha with the DNA repair protein XRCC1

9 July 2018

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9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333375

XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333375

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333375

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333375

Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333375

DNA strand break and rejoining in cultured human fibroblasts exposed to fast neutrons or gamma rays

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25539916

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PCR Mutagenesis by Overlap Extension and Gene SOE

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25539916

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKU1307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25539916 AND SRC:MED&resulttype=core&format=json

12 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25539916 AND SRC:MED&resulttype=core&format=json

12 June 2020

25539916

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25539916 AND SRC:MED&resulttype=core&format=json