The pathobiological mechanisms of emphysema models: what do they have in common? (Q35096901)

6 August 2017

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title

The pathobiological mechanisms of emphysema models: what do they have in common? (English)

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6 August 2017

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Rubin M Tuder

1

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6 August 2017

Sharon McGrath

series ordinal

2

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6 August 2017

Enid Neptune

series ordinal

3

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6 August 2017

publication date

1 January 2003

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6 August 2017

number of pages

12

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Pulmonary Pharmacology & Therapeutics

inferred from page(s)

published in

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6 August 2017

volume

16

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6 August 2017

issue

2

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6 August 2017

page(s)

67-78

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Site and Nature of Airway Obstruction in Chronic Obstructive Lung Disease

6 August 2017

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Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema

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7 January 2021

Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema

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7 January 2021

Effect of long-term exposure to cigarette smoke on the small airways of the guinea pig

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7 January 2021

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

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7 January 2021

Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease

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7 January 2021

The macrophage in chronic obstructive pulmonary disease

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7 January 2021

Augmentation of elastase-induced emphysema by cigarette smoke. Effects of reduced nicotine content

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7 January 2021

The induction of pulmonary emphysema with human leukocyte elastase

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7 January 2021

Ultrastructural changes in hamster lung 15 min to 3 hr after exposure to pancreatic elastase

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Young hamsters are more resistant than adults to endotracheally instilled porcine pancreatic elastase.

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7 January 2021

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

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7 January 2021

Interferon gamma induction of pulmonary emphysema in the adult murine lung

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7 January 2021

Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema

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7 January 2021

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3).

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7 January 2021

Airway inflammation and peribronchiolar attachments in the lungs of nonsmokers, current and ex-smokers

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7 January 2021

Amplification of inflammation in emphysema and its association with latent adenoviral infection

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7 January 2021

Emphysema: the first two centuries--and beyond. A historical overview, with suggestions for future research: Part 1

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7 January 2021

Activation of Neutrophils within Pulmonary Microvessels of Rabbits Exposed to Cigarette Smoke

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7 January 2021

Invited Review: pulmonary alveoli: formation, the "call for oxygen," and other regulators

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7 January 2021

Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues

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7 January 2021

Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide

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7 January 2021

Induction of emphysematous lesions in rat lung by beta-D-xyloside, an inhibitor of proteoglycan synthesis

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7 January 2021

Altered composition of urinary heparan sulfate in patients with COPD.

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7 January 2021

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation

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7 January 2021

Induction of skin fibrosis in mice expressing a mutated fibrillin-1 gene.

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7 January 2021

A role for CD4 T cells in the pathogenesis of skin fibrosis in tight skin mice

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7 January 2021

Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.

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7 January 2021

A 16-month study of the development of genetic emphysema in tight-skin mice

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7 January 2021

Hereditary emphysema in the tight-skin mouse. Evaluation of pathogenesis

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7 January 2021

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

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7 January 2021

Evidence that genetic emphysema in tight-skin mice is not caused by neutrophil elastase

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7 January 2021

Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G.

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7 January 2021

Lung collagen synthesis and deposition in tight-skin mice with genetic emphysema

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7 January 2021

The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency

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7 January 2021

Characterization of an in vitro model of elastic fiber assembly

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7 January 2021

PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis

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7 January 2021

Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo

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7 January 2021

Impaired distal airway development in mice lacking elastin.

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7 January 2021

Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice

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7 January 2021

Late pulmonary sequelae of bronchopulmonary dysplasia

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7 January 2021

Bronchopulmonary dysplasia

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7 January 2021

Bronchopulmonary dysplasia: "a vascular hypothesis".

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7 January 2021

Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons

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7 January 2021

Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia.

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7 January 2021

Inhibition of angiogenesis decreases alveolarization in the developing rat lung

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7 January 2021

Decreased alveolarization in baboon survivors with bronchopulmonary dysplasia

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7 January 2021

Mechanisms of cell injury and death in hyperoxia: role of cytokines and Bcl-2 family proteins

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7 January 2021

Selenite negatively regulates caspase-3 through a redox mechanism

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7 January 2021

Hyperoxia-induced cell death in the lung--the correlation of apoptosis, necrosis, and inflammation

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7 January 2021

Glutathione metabolism in newborns: evidence for glutathione deficiency in plasma, bronchoalveolar lavage fluid, and lymphocytes in prematures

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7 January 2021

Overexpression of manganous superoxide dismutase (MnSOD) in pulmonary endothelial cells confers resistance to hyperoxia

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7 January 2021

Antioxidant enzyme regulation and resistance to oxidants of human bronchial epithelial cells cultured under hyperoxic conditions

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7 January 2021

The effect of 60% oxygen on air-space enlargement and cross-linked elastin synthesis in hamsters with elastase-induced emphysema

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7 January 2021

Growth arrest in A549 cells during hyperoxic stress is associated with decreased cyclin B1 and increased p21(Waf1/Cip1/Sdi1) levels

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7 January 2021

Induction of p21WAF/CIP1 during Hyperoxia

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7 January 2021

Accumulation of p21(Cip1/WAF1) during hyperoxic lung injury in mice

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7 January 2021

Postnatal development of alveoli. Regulation and evidence for a critical period in rats

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7 January 2021

Impairment of rat postnatal lung alveolar development by glucocorticoids: involvement of the p21CIP1 and p27KIP1 cyclin-dependent kinase inhibitors

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7 January 2021

Dose-dependent lung remodeling in transgenic mice expressing transforming growth factor-alpha

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7 January 2021

Immunolocalization of transforming growth factor-alpha, epidermal growth factor (EGF), and EGF-receptor in normal and injured developing human lung

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7 January 2021

10.1016/S1094-5539(02)00099-8

Identifiers

DOI

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6 August 2017

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