Chfr and RNF8 synergistically regulate ATM activation (Q35089499)

6 August 2017

title

Chfr and RNF8 synergistically regulate ATM activation (English)

1 reference

6 August 2017

Jiaxue Wu

1

1 reference

6 August 2017

Yibin Chen

2

1 reference

6 August 2017

Lin-Yu Lu

3

1 reference

6 August 2017

Yipin Wu

4

1 reference

6 August 2017

Mats Ljungman

6

1 reference

6 August 2017

Xiaochun Yu

8

1 reference

6 August 2017

Michelle T. Paulsen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21706008

5 December 2024

David O. Ferguson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21706008

5 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21706008

5 December 2024

publication date

26 June 2011

1 reference

full work available at URL

6 August 2017

https://europepmc.org/articles/pmc3130800?pdf=render

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21706008

https://europepmc.org/articles/PMC3130800

5 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21706008

https://europepmc.org/articles/PMC3130800?pdf=render

5 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21706008

http://www.nature.com/articles/nsmb.2078.pdf

5 December 2024

1 reference

http://www.nature.com/articles/nsmb.2078

5 December 2024

1 reference

Nature Structural & Molecular Biology

5 December 2024

published in

1 reference

6 August 2017

volume

18

1 reference

6 August 2017

issue

7

1 reference

6 August 2017

page(s)

761-768

1 reference

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer

6 August 2017

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1 reference

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Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8

8 July 2018

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RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

8 July 2018

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8 July 2018

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Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

8 July 2018

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Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks

8 July 2018

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Regulatory ubiquitylation in response to DNA double-strand breaks

8 July 2018

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Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

8 July 2018

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Histone ubiquitination associates with BRCA1-dependent DNA damage response

8 July 2018

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Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

8 July 2018

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Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

8 July 2018

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FHA-RING ubiquitin ligases in cell division cycle control

8 July 2018

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Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

8 July 2018

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The DNA damage response: ten years after

8 July 2018

1 reference

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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

8 July 2018

1 reference

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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

8 July 2018

1 reference

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

8 July 2018

1 reference

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

8 July 2018

1 reference

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Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA-repair defects post exposure to gamma ionizing radiation

8 July 2018

1 reference

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Rapid activation of ATM on DNA flanking double-strand breaks

8 July 2018

1 reference

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DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

8 July 2018

1 reference

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Males absent on the first (MOF): from flies to humans.

8 July 2018

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Histone acetyltransferase complexes: one size doesn't fit all

8 July 2018

1 reference

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A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

8 July 2018

1 reference

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Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

8 July 2018

1 reference

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Surviving the breakup: the DNA damage checkpoint.

8 July 2018

1 reference

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Histone H4-K16 acetylation controls chromatin structure and protein interactions

8 July 2018

1 reference

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Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

8 July 2018

1 reference

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A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

8 July 2018

1 reference

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8 July 2018

ATM signaling and 53BP1.

1 reference

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Chfr is required for tumor suppression and Aurora A regulation

8 July 2018

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

8 July 2018

1 reference

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Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

8 July 2018

1 reference

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Chfr inactivation is not associated to chromosomal instability in colon cancers

8 July 2018

1 reference

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The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains

8 July 2018

1 reference

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Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex

8 July 2018

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Epigenetic inactivation of CHFR in human tumors

8 July 2018

1 reference

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Mechanism of ubiquitin recognition by the CUE domain of Vps9p

8 July 2018

1 reference

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130800

MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation

8 July 2018

1 reference

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Interfaces between the detection, signaling, and repair of DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130800

Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions

8 July 2018

1 reference

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The mechanism and regulation of chromosomal V(D)J recombination

8 July 2018

1 reference

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Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

8 July 2018

1 reference

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ATM, a central controller of cellular responses to DNA damage.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130800

N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8

8 July 2018

1 reference

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ATM: a mediator of multiple responses to genotoxic stress

8 July 2018

1 reference

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Crystal structure of the nucleosome core particle at 2.8 Å resolution

8 July 2018

1 reference

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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

8 July 2018

1 reference

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Atm-deficient mice: a paradigm of ataxia telangiectasia

8 July 2018

1 reference

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Leukemia and lymphoma in ataxia telangiectasia

8 July 2018

1 reference

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Juxtaposition of the T-cell receptor alpha-chain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia

8 July 2018

1 reference

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The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis

8 July 2018

1 reference

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High recurrence of rearrangements involving chromosome 14 in an ataxia telangiectasia lymphoblastoid cell line and in its mutagen-treated derivatives

8 July 2018

1 reference

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OsHAL3 mediates a new pathway in the light-regulated growth of rice.

8 July 2018

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DNA damage: ubiquitin marks the spot

21 January 2018

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Chromatin Fiber Folding: Requirement for the Histone H4 N-terminal Tail

21 January 2018

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The core histone N-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays

31 March 2020

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Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21706008

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2078

1 reference

6 August 2017

1 reference

6 August 2017

1 reference