Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds (Q35084931)

6 August 2017

title

Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds (English)

1 reference

6 August 2017

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4

Josephine M Egan

1 reference

6 August 2017

Hyekyung Yang

1

1 reference

6 August 2017

Wei-Na Cong

series ordinal

2

1 reference

6 August 2017

Jeong Seon Yoon

series ordinal

3

1 reference

6 August 2017

language of work or name

English

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publication date

30 October 2014

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6 August 2017

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6 August 2017

volume

4

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6 August 2017

issue

2

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6 August 2017

page(s)

245-252

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A phase I, multicenter, open-label, first-in-human, dose-escalation study of the oral smoothened inhibitor Sonidegib (LDE225) in patients with advanced solid tumors

6 August 2017

cites work

1 reference

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8 July 2018

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Altered lipid and salt taste responsivity in ghrelin and GOAT null mice

8 July 2018

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Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance

8 July 2018

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8 July 2018

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Lgr5-EGFP marks taste bud stem/progenitor cells in posterior tongue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Vismodegib and the hedgehog pathway: a new treatment for basal cell carcinoma

8 July 2018

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Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome

8 July 2018

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Efficacy and safety of vismodegib in advanced basal-cell carcinoma.

8 July 2018

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8 July 2018

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Taste receptor signalling – from tongues to lungs

8 July 2018

1 reference

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Roles of Hormones in Taste Signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

The cell biology of taste

8 July 2018

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Glucagon signaling modulates sweet taste responsiveness.

8 July 2018

1 reference

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Stem and progenitor cell compartments within adult mouse taste buds.

8 July 2018

1 reference

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Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

8 July 2018

1 reference

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GDC-0449-a potent inhibitor of the hedgehog pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Hormones in the naso-oropharynx: endocrine modulation of taste and smell

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

T1R3 taste receptor is critical for sucrose but not Polycose taste.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Basal cell carcinomas: attack of the hedgehog

8 July 2018

1 reference

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Modulation of taste sensitivity by GLP-1 signaling

8 July 2018

1 reference

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Amiloride-sensitive channels in type I fungiform taste cells in mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Cell lineage and differentiation in taste buds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

The receptors and cells for mammalian taste

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Cell communication in taste buds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Umami taste responses are mediated by alpha-transducin and alpha-gustducin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Hedgehog signaling in animal development: paradigms and principles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Molecular mechanisms of bitter and sweet taste transduction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome

8 July 2018

1 reference

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Activating Smoothened mutations in sporadic basal-cell carcinoma

8 July 2018

1 reference

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Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

8 July 2018

1 reference

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Transduction of bitter and sweet taste by gustducin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Renewal of cells within taste buds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

A strong nerve dependence of sonic hedgehog expression in basal cells in mouse taste bud and an autonomous transcriptional control of genes in differentiated taste cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Behavioral evidence for a role of alpha-gustducin in glutamate taste

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Detection of sweet and umami taste in the absence of taste receptor T1r3.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning: fungiform papillae double in number and form in novel locations in dorsal lingual epithelium

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

"Type III" cells of rat taste buds: immunohistochemical and ultrastructural studies of neuron-specific enolase, protein gene product 9.5, and serotonin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329008

Renewal of taste bud cells in rat circumvallate papillae

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25354792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeting the Hedgehog pathway in cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25354792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/CAM4.350

1 reference

6 August 2017

1 reference

6 August 2017

1 reference