Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells. (Q35083218)

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1 March 2020

title

Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells (English)

1 reference

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1 March 2020

1 reference

José A Campos-Sandoval

5

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Jan Albrecht

13

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1 March 2020

Javier Márquez Gómez

15

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1 March 2020

Alison Colquhoun

16

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1 March 2020

José M. Matés

18

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1 March 2020

14

Rui Curi

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1 March 2020

17

Ralph J Deberardinis

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1 March 2020

12

Monika Szeliga

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1 March 2020

author name string

Mercedes Martín-Rufián

1

1 reference

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1 March 2020

Renata Nascimento-Gomes

2

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1 March 2020

Ana Higuero

3

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1 March 2020

Amanda R Crisma

4

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1 March 2020

María C Gómez-García

6

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Carolina Cardona

7

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Tzuling Cheng

8

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Carolina Lobo

9

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Juan A Segura

10

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Francisco J Alonso

11

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publication date

26 November 2013

1 reference

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Journal of Molecular Medicine

1 March 2020

published in

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volume

92

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issue

3

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page(s)

277-290

1 reference

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Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells

1 March 2020

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Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents

8 July 2018

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Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo

8 July 2018

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Mammalian glutaminase Gls2 gene encodes two functional alternative transcripts by a surrogate promoter usage mechanism

8 July 2018

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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

8 July 2018

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Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

8 July 2018

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Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation.

8 July 2018

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Metabolism of [U-13 C]glucose in human brain tumors in vivo

8 July 2018

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The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.

8 July 2018

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Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells.

8 July 2018

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Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia

8 July 2018

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Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

8 July 2018

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Anticancer antioxidant regulatory functions of phytochemicals.

8 July 2018

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Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.

8 July 2018

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Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

8 July 2018

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

8 July 2018

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

8 July 2018

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Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

8 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

8 July 2018

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A novel glutaminase isoform in mammalian tissues.

8 July 2018

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New insights into brain glutaminases: beyond their role on glutamatergic transmission.

8 July 2018

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8 July 2018

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Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells.

8 July 2018

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8 July 2018

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8 July 2018

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MYC, microRNAs and glutamine addiction in cancers

8 July 2018

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Antisense glutaminase inhibition modifies the O-GlcNAc pattern and flux through the hexosamine pathway in breast cancer cells.

27 September 2018

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Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24276018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00109-013-1105-2

1 reference

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24276018 AND SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24276018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24276018 AND SRC:MED&resulttype=core&format=json