Mutator phenotype of Caenorhabditis elegans DNA damage checkpoint mutants (Q35083072)

6 August 2017

title

Mutator phenotype of Caenorhabditis elegans DNA damage checkpoint mutants (English)

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6 August 2017

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Caenorhabditis elegans

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1 reference

3

Iuval Clejan

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6 August 2017

Jasper Harris

1

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6 August 2017

Mia Lowden

2

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6 August 2017

Monika Tzoneva

4

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6 August 2017

James H Thomas

5

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6 August 2017

Jonathan Hodgkin

6

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6 August 2017

Shawn Ahmed

7

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6 August 2017

language of work or name

English

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publication date

1 September 2006

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6 August 2017

number of pages

16

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inferred from page(s)

published in

Genetics

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6 August 2017

volume

174

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6 August 2017

issue

2

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6 August 2017

page(s)

601-616

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Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS.

6 August 2017

cites work

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8 July 2018

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trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase

8 July 2018

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A conserved checkpoint monitors meiotic chromosome synapsis in Caenorhabditis elegans

8 July 2018

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Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans

8 July 2018

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Transposition of ISHp608, member of an unusual family of bacterial insertion sequences

8 July 2018

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Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization

8 July 2018

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The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair

8 July 2018

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Diverse DNA transposons in rotifers of the class Bdelloidea

8 July 2018

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RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair

8 July 2018

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End-joining repair of double-strand breaks in Drosophila melanogaster is largely DNA ligase IV independent

8 July 2018

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The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models

8 July 2018

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8 July 2018

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Breakpoints of gross deletions coincide with non-B DNA conformations

8 July 2018

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Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination

8 July 2018

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Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality

8 July 2018

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Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila

8 July 2018

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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

8 July 2018

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Methods for analyzing checkpoint responses in Caenorhabditis elegans

8 July 2018

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Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

8 July 2018

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Encoded errors: mutations and rearrangements mediated by misalignment at repetitive DNA sequences

8 July 2018

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Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

8 July 2018

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Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences

8 July 2018

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Mouse models for induced genetic instability at endogenous loci

8 July 2018

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Mechanism and regulation of human non-homologous DNA end-joining

8 July 2018

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Translocation and gross deletion breakpoints in human inherited disease and cancer I: Nucleotide composition and recombination-associated motifs

8 July 2018

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8 July 2018

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Ku-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae.

8 July 2018

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Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi

8 July 2018

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Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

8 July 2018

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Checkpoint activation regulates mutagenic translesion synthesis

8 July 2018

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The Fanconi anaemia/BRCA pathway

8 July 2018

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Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae

8 July 2018

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Human gene mutation in pathology and evolution

8 July 2018

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Biallelic inactivation of BRCA2 in Fanconi anemia

8 July 2018

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Cancer susceptibility and the functions of BRCA1 and BRCA2

8 July 2018

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Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

8 July 2018

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Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

8 July 2018

1 reference

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C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

8 July 2018

1 reference

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The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Rolling-circle transposons in eukaryotes

8 July 2018

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BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

BRCA2 is required for homology-directed repair of chromosomal breaks

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress

8 July 2018

1 reference

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DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

8 July 2018

1 reference

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Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

8 July 2018

1 reference

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Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation

8 July 2018

1 reference

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Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9

8 July 2018

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Brca1 controls homology-directed DNA repair

8 July 2018

1 reference

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Crossing over during Caenorhabditis elegans meiosis requires a conserved MutS-based pathway that is partially dispensable in budding yeast

8 July 2018

1 reference

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Involvement of Brca2 in DNA Repair

8 July 2018

1 reference

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Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1

8 July 2018

1 reference

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Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage

8 July 2018

1 reference

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DNA double-strand breaks caused by replication arrest

8 July 2018

1 reference

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Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins

8 July 2018

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Determination of life-span in Caenorhabditis elegans by four clock genes

8 July 2018

1 reference

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

8 July 2018

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8 July 2018

1 reference

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Molecular and genetic analyses of the Caenorhabditis elegans dpy-2 and dpy-10 collagen genes: a variety of molecular alterations affect organismal morphology

8 July 2018

1 reference

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Differential roles of the transposon termini in IS91 transposition

8 July 2018

1 reference

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Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair

8 July 2018

1 reference

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The Caenorhabditis elegans unc-60 gene encodes proteins homologous to a family of actin-binding proteins

8 July 2018

1 reference

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The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development

8 July 2018

1 reference

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Recombination of Ty elements in yeast can be induced by a double-strand break

8 July 2018

1 reference

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p53 wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutation in liver, spleen and brain.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Radiation-sensitive mutants of Caenorhabditis elegans

8 July 2018

1 reference

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The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains

8 July 2018

1 reference

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The genetics of Caenorhabditis elegans

8 July 2018

1 reference

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Structures of spontaneous deletions in Caenorhabditis elegans

8 July 2018

1 reference

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Genetic analysis of the cha-1-unc-17 gene complex in Caenorhabditis.

8 July 2018

1 reference

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Capture of flanking DNA by a P element in Drosophila melanogaster: creation of a transposable element

8 July 2018

1 reference

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A P element chimera containing captured genomic sequences was recovered at the vestigial locus in Drosophila following targeted transposition

8 July 2018

1 reference

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Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites.

8 July 2018

1 reference

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Gene interactions in Caenorhabditis elegans define DPY-31 as a candidate procollagen C-proteinase and SQT-3/ROL-4 as its predicted major target

27 September 2018

1 reference

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Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast

27 September 2018

1 reference

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Critical role for chicken Rad17 and Rad9 in the cellular response to DNA damage and stalled DNA replication

27 September 2018

1 reference

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Translocation and gross deletion breakpoints in human inherited disease and cancer II: Potential involvement of repetitive sequence elements in secondary structure formation between DNA ends

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Combined functional genomic maps of the C. elegans DNA damage response

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

27 September 2018

1 reference

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Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602097

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

27 September 2018

1 reference

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vab-8 Is a Key Regulator of Posteriorly Directed Migrations in C. elegans and Encodes a Novel Protein with Kinesin Motor Similarity

27 September 2018

1 reference

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Spontaneous mutation frequencies and spectra in p53 ( / ) and p53 (-/-) mice: a test of the 'guardian of the genome' hypothesis in the Big Blue transgenic mouse mutation detection system

27 September 2018

1 reference

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Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans

27 September 2018

1 reference

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Screening for germ-line rearrangements and regulatory mutations in BRCA1 led to the identification of four new deletions

27 September 2018

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12 December 2020

Prevalence of five previously reported and recurrent BRCA1 genetic rearrangement mutations in 20,000 patients from hereditary breast/ovarian cancer families

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12 December 2020

Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments

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12 December 2020

A novel K( )-dependent DNA synthesis arrest site in a commonly occurring sequence motif in eukaryotes

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12 December 2020

10.1534/GENETICS.106.058701

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference