Pleiotropic Functions of the Organic Solute Transporter Ostα-Ostβ (Q35082229)

6 August 2017

1 reference

title

Pleiotropic Functions of the Organic Solute Transporter Ostα-Ostβ (English)

1 reference

5 December 2024

1 reference

Nazzareno Ballatori

1

1 reference

6 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21691099

5 December 2024

publication date

17 June 2011

1 reference

full work available at URL

6 August 2017

https://www.karger.com/Article/Pdf/324123

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21691099

https://europepmc.org/articles/PMC3128137

5 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21691099

https://europepmc.org/articles/PMC3128137?pdf=render

5 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21691099

https://doi.org/10.1159/000324123

5 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21691099

https://www.karger.com/Article/Pdf/324123

5 December 2024

1 reference

5 December 2024

1 reference

6 August 2017

volume

29

1 reference

6 August 2017

issue

1

1 reference

6 August 2017

page(s)

13-17

1 reference

The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain

6 August 2017

cites work

1 reference

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Neurosteroid transport by the organic solute transporter OSTα-OSTβ.

8 July 2018

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Counter-regulatory role of bile acid activated receptors in immunity and inflammation

8 July 2018

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Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism

8 July 2018

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Bile acids as regulators of hepatic lipid and glucose metabolism

8 July 2018

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Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis

8 July 2018

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Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms

8 July 2018

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Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system.

8 July 2018

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Bile alcohols function as the ligands of membrane-type bile acid-activated G protein-coupled receptor

8 July 2018

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Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?

8 July 2018

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Structure-activity relationship of bile alcohols as human farnesoid X receptor agonist

8 July 2018

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Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes

8 July 2018

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Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis

8 July 2018

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Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential

8 July 2018

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The bile acid synthesis pathway is present and functional in the human ovary

8 July 2018

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Oleanolic acid is a selective farnesoid X receptor modulator

8 July 2018

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Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones

8 July 2018

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Bile acids as regulatory molecules

8 July 2018

1 reference

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Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio

8 July 2018

1 reference

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OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids

8 July 2018

1 reference

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Role of bile acids and bile acid receptors in metabolic regulation

8 July 2018

1 reference

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FXR: a metabolic regulator and cell protector

8 July 2018

1 reference

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Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

Arachidonic acid-induced expression of the organic solute and steroid transporter-beta (Ost-beta) in a cartilaginous fish cell line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

8 July 2018

1 reference

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5Alpha-bile alcohols function as farnesoid X receptor antagonists

8 July 2018

1 reference

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Biology of a novel organic solute and steroid transporter, OSTalpha-OSTbeta

8 July 2018

1 reference

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The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets

8 July 2018

1 reference

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Functional Complementation between a Novel Mammalian Polygenic Transport Complex and an Evolutionarily Ancient Organic Solute Transporter, OSTα-OSTβ

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128137

Expression cloning of two genes that together mediate organic solute and steroid transport in the liver of a marine vertebrate

8 July 2018

1 reference

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The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution

8 July 2018

1 reference

Crossref

Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5.

21 January 2018

1 reference

Crossref

Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21691099

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1159/000324123

1 reference

6 August 2017

1 reference

6 August 2017

1 reference