The role of circulating IGF-I: lessons from human and animal models (Q35080570)

6 August 2017

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title

The role of circulating IGF-I: lessons from human and animal models (English)

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6 August 2017

1

Shoshana Yakar

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6 August 2017

Yiping Wu

2

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6 August 2017

Jennifer Setser

series ordinal

3

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6 August 2017

Clifford J Rosen

series ordinal

4

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6 August 2017

publication date

1 December 2002

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6 August 2017

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6 August 2017

volume

19

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6 August 2017

issue

3

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6 August 2017

page(s)

239-248

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Postnatal and pubertal skeletal changes contribute predominantly to the differences in peak bone density between C3H/HeJ and C57BL/6J mice

6 August 2017

cites work

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12 December 2020

Insulin resistance--mechanisms, syndromes, and implications

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12 December 2020

Serum levels of insulin-like growth factor-I in operable breast cancer in relation to the main prognostic variables and their perioperative changes in relation to those of prolactin

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12 December 2020

Expression of insulin-like growth factor-I in transgenic mice

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12 December 2020

Igf-independent regulation of breast cancer growth by IGF binding proteins

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12 December 2020

Growth hormone therapy for protein catabolism

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12 December 2020

Overexpression of the acid-labile subunit of the IGF ternary complex in transgenic mice

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12 December 2020

Circulating levels of IGF-1 directly regulate bone growth and density

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12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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12 December 2020

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

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12 December 2020

Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice.

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12 December 2020

Insulin-like growth factor I: physiology, metabolic effects and clinical uses

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12 December 2020

Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia

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12 December 2020

IGFBP-3 gene expression and estrogen receptor status in human breast carcinoma

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12 December 2020

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

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12 December 2020

Transgenic models of growth hormone action

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12 December 2020

Insulin-like growth factor (IGF) and IGF-binding proteins: comparison of human serum and lymph

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12 December 2020

Divergent responses of serum insulin-like growth factor-I and liver growth hormone (GH) receptors to exogenous GH in protein-restricted rats.

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12 December 2020

Nutritional regulation of the insulin-like growth factors

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12 December 2020

Regulation of insulin-like growth factor-I and growth hormone receptor gene expression by diabetes and nutritional state in rat tissues

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12 December 2020

Role of IGF-I in muscular atrophy of aging

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12 December 2020

Normal growth and development in the absence of hepatic insulin-like growth factor I

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12 December 2020

Responses of young energy-restricted sheep to chronically administered insulin-like growth factor I (IGF-I): evidence that IGF-I suppresses the hepatic growth hormone receptor

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12 December 2020

Receptor-specific induction of insulin-like growth factor I in human monocytes by advanced glycosylation end product-modified proteins

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12 December 2020

Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system

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12 December 2020

The insulin-like growth factor system and the coupling of formation to resorption

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12 December 2020

Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells

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12 December 2020

Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation

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12 December 2020

Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5.

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12 December 2020

Regulation of insulin-like growth factor I gene expression by growth hormone

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12 December 2020

The roles of prolactin, growth hormone, insulin-like growth factor-I, and thyroid hormones in lymphocyte development and function: insights from genetic models of hormone and hormone receptor deficiency

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12 December 2020

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

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12 December 2020

Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain

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12 December 2020

Total calories, body weight, and tumor incidence in mice.

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12 December 2020

Genetic engineering in mice: impact on insulin signalling and action.

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12 December 2020

Thyroid hormone and glucocorticoid regulation of pituitary growth hormone-releasing hormone receptor gene expression

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12 December 2020

Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4

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12 December 2020

Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity

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12 December 2020

Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues

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12 December 2020

Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women

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12 December 2020

Insulin-Like Growth Factor Binding Protein Secretion by Breast Carcinoma Cell Lines: Correlation with Estrogen Receptor Status*

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12 December 2020

Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure

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12 December 2020

Growth hormone stimulates longitudinal bone growth directly

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12 December 2020

Insulin-like growth factor-I reverses the impairment of wound healing induced by corticosteroids in rats

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12 December 2020

Inhibition of GH release of rats by new potent antagonists of growth hormone-releasing hormone (GH-RH).

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12 December 2020

Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: repercussions on reproduction, ante- and perinatal mortality and postnatal growth

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12 December 2020

Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study

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12 December 2020

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

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12 December 2020

Identification of enhanced serine kinase activity in insulin resistance

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12 December 2020

Insulin-like growth factors and bone: the osteoporosis connection revisited

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12 December 2020

Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid

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12 December 2020

Influence of Hypothyroidism on Growth Hormone Binding by Rat Liver*

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12 December 2020

Human insulin-like growth factor-binding protein-1 (hIGFBP-1) in transgenic mice: characterization and insights into the regulation of IGFBP-1 expression

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12 December 2020

Sequence of two rat insulin-like growth factor I mRNAs differing within the 5' untranslated region

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12 December 2020

Interferon-gamma inhibits macrophage insulin-like growth factor-I synthesis at the transcriptional level

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12 December 2020

The colony-stimulating factors induce expression of insulin-like growth factor-I messenger ribonucleic acid during hematopoiesis

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12 December 2020

Insulin-like growth factors and bone: the osteoporosis connection

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12 December 2020

Transcapillary Permeability and Subendothelial Distribution of Endothelial and Amniotic Fluid Insulin- Like Growth Factor Binding Proteins in the Rat Heart*

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12 December 2020

Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides

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12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

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12 December 2020

Role of insulin-like growth factors in embryonic and postnatal growth

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12 December 2020

Anabolic effects of insulin-like growth factor-I (IGF-I) and an IGF-I variant in normal female rats

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12 December 2020

Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice

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12 December 2020

Effects of growth hormone and insulin-like growth factor I on renal growth and function

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12 December 2020

The insulin-like growth factor I receptor: a key to tumor growth?

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12 December 2020

Growth factor binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors from rats subject to chronic caloric restriction

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12 December 2020

Plasma insulin-like growth factor-1 (IGF-1) concentrations in human breast cancer

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12 December 2020

Prognostic Significance of Insulin-like Growth Factor-Binding Protein Expression in Axillary Lymph Node-Negative Breast Cancer

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12 December 2020

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

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12 December 2020

The somatomedin hypothesis: 2001.

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12 December 2020

Insulin-like growth factor I and its binding proteins in the cardiovascular system

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12 December 2020

Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells. Role of cathepsin D.

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12 December 2020

The differential regulation by glucagon and growth hormone of insulin-like growth factor (IGF)-I and IGF binding proteins in cultured rat hepatocytes

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12 December 2020

The crucial role of a phosphatase in insulin resistance and obesity.

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12 December 2020

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice

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12 December 2020

Effects of hypothyroidism and hyperthyroidism on insulin-like growth factors (IGFs) and growth hormone- and IGF-binding proteins

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12 December 2020

Insulin-like growth factor I acts as an angiogenic agent in rabbit cornea and retina: comparative studies with basic fibroblast growth factor

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12 December 2020

Differential regulation of transcription initiation from insulin-like growth factor-I (IGF-I) leader exons and of tissue IGF-I expression in response to changed growth hormone and nutritional status in sheep

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12 December 2020

Effects of food deprivation on the GH axis: immunocytochemical and molecular analysis

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12 December 2020

Functional switching of macrophage responses to tumor necrosis factor-alpha (TNF alpha) by interferons. Implications for the pleiotropic activities of TNF alpha

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12 December 2020

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

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12 December 2020

Growth hormone-induced insulin resistance: role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4

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12 December 2020

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

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12 December 2020

Chromatin changes accompany the developmental activation of insulin-like growth factor I gene transcription

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12 December 2020

Insulin-like growth factor-I, but not growth hormone, is dependent on a high protein intake to increase nitrogen balance in the rat

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12 December 2020

Effect of chronic growth hormone treatment on insulin signal transduction in rat tissues

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12 December 2020

Skeletal growth of transgenic mice with elevated levels of circulating insulin-like growth factor-II.

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12 December 2020

Differential effects of estrogen and growth hormone on uterine and hepatic insulin-like growth factor I gene expression in the ovariectomized hypophysectomized rat

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12 December 2020

Expression of human insulin-like growth factor-binding protein-3 in transgenic mice.

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12 December 2020

Growth hormone-induced alterations in the insulin-signaling system

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12 December 2020

Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model

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12 December 2020

Immunoreactive prostate-specific antigen levels in female and male breast tumors and its association with steroid hormone receptors and patient age

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12 December 2020

Cloning of ovine insulin-like growth factor-I cDNAs: heterogeneity in the mRNA population

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12 December 2020

Regulation of Start Site Usage in the Leader Exons of the Rat Insulin-Like Growth Factor-I Gene by Development, Fasting, and Diabetes

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12 December 2020

High-risk colorectal adenomas and serum insulin-like growth factors

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12 December 2020

Evidence that somatomedin is synthesized by multiple tissues in the fetus

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12 December 2020

Co-expression of bovine growth hormone (GH) and human GH antagonist genes in transgenic mice

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12 December 2020

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action

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12 December 2020

Insulin-like growth factors and their binding proteins: biological actions

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12 December 2020

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

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12 December 2020

Stimulation of growth in the little mouse

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12 December 2020

Insulinlike growth factor I and interleukin 1 beta messenger RNA in a rat model of granulomatous enterocolitis and hepatitis

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12 December 2020

Down regulation of masked and unmasked insulin receptors in the liver of transgenic mice expressing bovine growth hormone gene

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12 December 2020

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

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12 December 2020

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

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12 December 2020

Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis

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12 December 2020

The skeletal structure of insulin-like growth factor I-deficient mice

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12 December 2020

Tumor markers in patients with advanced breast cancer as prognosticators: a preliminary study

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12 December 2020

Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins

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12 December 2020

Regulation of Insulin-Like Growth Factor-Binding Protein (IGFBP) Expression by Breast Cancer Cells: Use of IGFBP-1 as as Inhibitor of Insulin-like Growth Factor Action

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12 December 2020

Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study

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12 December 2020

Expression of insulin-like growth factor binding proteins (IGFBPs) in IGFBP-1 transgenic mice

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12 December 2020

Modifications of insulin-like growth factor binding proteins and their role in controlling IGF actions

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12 December 2020

Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene.

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12 December 2020

Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E-peptides: evidence for differential processing and regulation in liver

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12 December 2020

Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo

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12 December 2020

Overexpression of bovine growth hormone in transgenic mice is associated with changes in hepatic insulin receptors and in their kinase activity

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12 December 2020

Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice

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12 December 2020

Effects of local administration of GH and IGF-1 on longitudinal bone growth in rats

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12 December 2020

Transcriptional repression of insulin-like growth factor I by glucocorticoids in rat bone cells

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12 December 2020

Does recombinant human insulin-like growth factor-1 have a role in the treatment of diabetes?

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12 December 2020

Functional analysis of the rat insulin-like growth factor I gene and identification of an IGF-I gene promoter

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12 December 2020

Acromegaly, colonic polyps and carcinoma

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12 December 2020

Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study

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12 December 2020

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice

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12 December 2020

Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis

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12 December 2020

Fibrogenic cytokines and connective tissue production

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12 December 2020

Benefit of systemically administered rhIGF-I and rhIGF-I/IGFBP-3 on cancellous bone in ovariectomized rats

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12 December 2020

Murine macrophages express abundant insulin-like growth factor-I class I Ea and Eb transcripts

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12 December 2020

Insulin-like growth factor-I affects perinatal lethality and postnatal development in a gene dosage-dependent manner: manipulation using the Cre/loxP system in transgenic mice.

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12 December 2020

IGF-I is required for normal embryonic growth in mice

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12 December 2020

Tissue and development specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids.

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12 December 2020

Molecular cloning and expression of a pituitary-specific receptor for growth hormone-releasing hormone

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12 December 2020

Nutritional regulation of IGF-I and IGFBPs.

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12 December 2020

Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.

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12 December 2020

Cytokines modulate the sensitivity of human fibroblasts to stimulation with insulin-like growth factor-I (IGF-I) by altering endogenous IGF-binding protein production

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12 December 2020

Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes

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12 December 2020

Insulin-like growth factors and cancer

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12 December 2020

Brain growth retardation due to the expression of human insulin like growth factor binding protein-1 in transgenic mice: an in vivo model for the analysis of igf function in the brain

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12 December 2020

Biological and clinical relevance of the urokinase-type plasminogen activator (uPA) in breast cancer

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12 December 2020

Identifiers

DOI

10.1385/ENDO:19:3:239

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Dimensions Publication ID

6 August 2017

1045305327

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