Developmental aspects of the endocrine pancreas (Q35078465)

6 August 2017

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title

Developmental aspects of the endocrine pancreas (English)

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6 August 2017

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3

Joel F Habener

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6 August 2017

Daniel M Kemp

1

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6 August 2017

Melissa K Thomas

series ordinal

2

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6 August 2017

publication date

1 March 2003

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Reviews in Endocrine and Metabolic Disorders

6 August 2017

published in

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6 August 2017

volume

4

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6 August 2017

issue

1

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6 August 2017

page(s)

5-17

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Islet growth and development in the adult

6 August 2017

cites work

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12 December 2020

A bipotential precursor population for pancreas and liver within the embryonic endoderm.

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12 December 2020

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia

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12 December 2020

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

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12 December 2020

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

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12 December 2020

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

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12 December 2020

Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

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12 December 2020

Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

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12 December 2020

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

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12 December 2020

The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration

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12 December 2020

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

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12 December 2020

Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue

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12 December 2020

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

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12 December 2020

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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12 December 2020

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

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12 December 2020

Activin receptor patterning of foregut organogenesis

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12 December 2020

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

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12 December 2020

Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas

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12 December 2020

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

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12 December 2020

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model

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12 December 2020

Expression of neurogenin3 reveals an islet cell precursor population in the pancreas

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12 December 2020

The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

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12 December 2020

Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats

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12 December 2020

Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor

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12 December 2020

Perspective: Postnatal pancreatic beta cell growth

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12 December 2020

The role of PTF1-P48 in pancreatic acinar gene expression

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12 December 2020

Wingless and Hedgehog pattern Drosophila denticle belts by regulating the production of short-range signals

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12 December 2020

Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells

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12 December 2020

Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations

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12 December 2020

Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells

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12 December 2020

Extra-insular beta cells associated with ductules are frequent in adult human pancreas

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12 December 2020

Notch-mediated segmentation and growth control of the Drosophila leg.

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12 December 2020

Notch signaling: cell fate control and signal integration in development

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12 December 2020

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

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12 December 2020

Developmental biology of the pancreas

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12 December 2020

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes

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12 December 2020

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

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12 December 2020

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo

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12 December 2020

Sonic hedgehog is essential to foregut development

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12 December 2020

Notochord repression of endodermal Sonic hedgehog permits pancreas development

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12 December 2020

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

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12 December 2020

Notch signalling controls pancreatic cell differentiation

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12 December 2020

Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites

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12 December 2020

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

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12 December 2020

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12 December 2020

Regulatory factor linked to late-onset diabetes?

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12 December 2020

Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

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12 December 2020

The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus

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12 December 2020

Identification of missense mutations in the hepatocyte nuclear factor-3beta gene in Japanese subjects with late-onset Type II diabetes mellitus

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12 December 2020

Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells

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12 December 2020

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

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12 December 2020

Hepatocyte Nuclear Factor 3β is Involved in Pancreatic β-Cell-Specific Transcription of the pdx-1 Gene

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12 December 2020

Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period

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12 December 2020

Development of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1

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12 December 2020

Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation

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12 December 2020

Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants

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12 December 2020

Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

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12 December 2020

Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice

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12 December 2020

Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9

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12 December 2020

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

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12 December 2020

Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny

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12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

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12 December 2020

Regulation of the pancreatic pro-endocrine gene neurogenin3.

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12 December 2020

Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

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12 December 2020

Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo

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12 December 2020

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes

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12 December 2020

Hedgehog signaling regulation of insulin production by pancreatic beta-cells

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12 December 2020

Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

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12 December 2020

Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor

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12 December 2020

Ontogeny, differentiation and growth of the endocrine pancreas

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12 December 2020

p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos

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12 December 2020

Origin of endothelial progenitors in human postnatal bone marrow

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12 December 2020

HNF-3 beta is essential for node and notochord formation in mouse development

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12 December 2020

Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development.

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12 December 2020

Glucagon-like peptide-1: a major regulator of pancreatic beta-cell function

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12 December 2020

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation

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12 December 2020

Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans

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12 December 2020

Pancreas development and diabetes

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12 December 2020

Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo

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12 December 2020

Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells

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12 December 2020

Transcribing pancreas

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12 December 2020

Regulation of pancreas development by hedgehog signaling

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12 December 2020

Control of endodermal endocrine development by Hes-1

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12 December 2020

Laron Dwarfism and Non-Insulin-Dependent Diabetes Mellitus in the Hnf-1α Knockout Mouse

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12 December 2020

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

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12 December 2020

Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes

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12 December 2020

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

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12 December 2020

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells

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12 December 2020

Adaptation of Islets of Langerhans to Pregnancy: β-Cell Growth, Enhanced Insulin Secretion and the Role of Lactogenic Hormones

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12 December 2020

The development of the dorsal and ventral mammalian pancreas in vivo and in vitro

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12 December 2020

Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors

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12 December 2020

A pancreatic beta -cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta ), HNF-1alpha, and SPs transcription factors

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12 December 2020

TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro

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12 December 2020

Insulin-promoter-factor 1 is required for pancreas development in mice

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12 December 2020

Transdifferentiation versus stem cell hypothesis for the regeneration of islet beta-cells in the pancreas

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12 December 2020

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

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12 December 2020

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice

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12 December 2020

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

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12 December 2020

The activity of neurogenin1 is controlled by local cues in the zebrafish embryo

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12 December 2020

Identifiers

DOI

10.1023/A:1021809917576

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Dimensions Publication ID

6 August 2017

1036257040

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