Cytoplasmic delivery and nuclear targeting of synthetic macromolecules (Q35078380)

6 August 2017

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title

Cytoplasmic delivery and nuclear targeting of synthetic macromolecules (English)

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6 August 2017

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Keith D Jensen

1

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6 August 2017

Aparna Nori

2

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6 August 2017

Monica Tijerina

3

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6 August 2017

Pavla Kopecková

4

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6 August 2017

Jindrich Kopecek

5

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Journal of Controlled Release

6 August 2017

published in

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6 August 2017

volume

87

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6 August 2017

issue

1-3

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6 August 2017

page(s)

89-105

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Cellular delivery of antisense oligonucleotides

6 August 2017

cites work

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7 January 2021

Molecular mechanisms of action of antisense drugs

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7 January 2021

Responsive polymeric delivery systems.

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7 January 2021

HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

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7 January 2021

Solute translocation across the mammalian lysosome membrane

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7 January 2021

Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells

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7 January 2021

Commentary. Lysosomotropic agents

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7 January 2021

Controlled biodegradability of polymers — a key to drug delivery systems

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7 January 2021

Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules

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7 January 2021

The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells

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7 January 2021

HPMA-based biodegradable hydrogels containing different forms of doxorubicin. Antitumor effects and biocompatibility.

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7 January 2021

Release of macromolecules and daunomycin from hydrophilic gels containing enzymatically degradable bonds

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7 January 2021

Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains.

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7 January 2021

Self-assembled peptides exposing epitopes recognizable by human lymphoma cells

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7 January 2021

Presentation of epitopes on genetically engineered peptides and selection of lymphoma-targeting moieties based on epitope biorecognition

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7 January 2021

Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers

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7 January 2021

Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers

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7 January 2021

Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases

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7 January 2021

Immunogenicity of N-(2-hydroxypropyl)-methacrylamide copolymers--potential hapten or drug carriers

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7 January 2021

Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice

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7 January 2021

New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism

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7 January 2021

Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

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7 January 2021

High-molecular weight HPMA copolymer-adriamycin conjugates

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7 January 2021

The influence of cytotoxicity of macromolecules and of VEGF gene modulated vascular permeability on the enhanced permeability and retention effect in resistant solid tumors

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration in the rat

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers a potential drug delivery system

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate.

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

HPMA copolymer–anticancer drug–OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Fomivirsen - a phosphorothioate oligonucleotide for the treatment of CMV retinitis

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Antisense therapy in oncology: new hope for an old idea?

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Antisense oligonucleotides delivered to the lysosome escape and actively inhibit the hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Hepatic distribution of a phosphorothioate oligodeoxynucleotide within rodents following intravenous administration

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e6 does not induce P-glycoprotein-mediated multidrug resistance.

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

The effects of subcellular localization of N-(2-hydroxypropyl)methacrylamide copolymer-Mce(6) conjugates in a human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Dissection of a nuclear localization signal

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Pinocytosis in the rat visceral yolk sac effects of temperature, metabolic inhibitors and some other modifiers

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Cell-penetrating peptides.

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Protein transduction: unrestricted delivery into all cells?

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https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

In vivo protein transduction: delivery of a biologically active protein into the mouse

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1016/S0168-3659(02)00352-8

7 January 2021

10.1016/S0168-3659(02)00352-8

Identifiers

DOI

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6 August 2017

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