Transmembrane adapters: attractants for cytoplasmic effectors (Q35076700)

6 August 2017

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title

Transmembrane adapters: attractants for cytoplasmic effectors (English)

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6 August 2017

main subject

transmembrane protein

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author name string

Jonathan A Lindquist

series ordinal

1

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6 August 2017

Luca Simeoni

series ordinal

2

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6 August 2017

Burkhart Schraven

series ordinal

3

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6 August 2017

publication date

1 February 2003

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6 August 2017

published in

Immunological Reviews

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6 August 2017

volume

191

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6 August 2017

page(s)

165-182

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Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids.

21 January 2018

1 reference

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Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif

21 January 2018

1 reference

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Palmitoylation of either Cys-3 or Cys-5 is required for the biological activity of the Lck tyrosine protein kinase

21 January 2018

1 reference

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Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction

21 January 2018

1 reference

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Activation of human T cells is associated with tyrosine phosphorylation of several cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Tyrosine phosphorylation and translocation of LAT in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Essential role of LAT in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Identification of the minimal tyrosine residues required for linker for activation of T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Csk controls antigen receptor-mediated development and selection of T-lineage cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk).

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Antigen receptor tail clue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Requirement of the SH3 and SH2 domains for the inhibitory function of tyrosine protein kinase p50csk in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Cutting Edge: Transmembrane phosphoprotein Csk-binding protein/phosphoprotein associated with glycosphingolipid-enriched microdomains as a negative feedback regulator of mast cell signaling through the FcepsilonRI

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Transcriptional control of T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Coupling of Ras and Rac Guanosine Triphosphatases Through the Ras Exchanger Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Disruption of T cell signaling networks and development by Grb2 haploid insufficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Genomic organization and chromosomal localization of the human gene encoding the T-cell receptor-interacting molecule (TRIM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Developmentally regulated expression of the transmembrane adaptor protein trim in fetal and adult T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Brefeldin A: insights into the control of membrane traffic and organelle structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

BLNK: a central linker protein in B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Functional complementation of BLNK by SLP-76 and LAT linker proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

The p85 Subunit of Phosphatidylinositol 3-Kinase Associates with the Fc Receptor γ-Chain and Linker for Activitor of T Cells (LAT) in Platelets Stimulated by Collagen and Convulxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Molecular alterations of the Fyn-complex occur as late events of human T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

LAT, the Linker for Activation of T Cells: A Bridge Between T Cell-Specific and General Signaling Pathways

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Binding of Vav to Grb2 through dimerization of Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Aggregation of the high-affinity IgE receptor and enhanced activity of p53/56lyn protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes.

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

p21ras mediates control of IL-2 gene promoter function in T cell activation.

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

BLNK: connecting Syk and Btk to calcium signals

1 reference

https://api.crossref.org/works/10.1034/J.1600-065X.2003.00007.X

7 January 2021

10.1034/J.1600-065X.2003.00007.X

Identifiers

DOI

1 reference

6 August 2017

1 reference