Signal dispersal and transduction through the endocytic pathway (Q35075762)

6 August 2017

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title

Signal dispersal and transduction through the endocytic pathway (English)

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6 August 2017

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Marcos Gonzalez-Gaitan

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ORCID Public Data File 2021

author name string

Marcos González-Gaitán

series ordinal

1

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6 August 2017

publication date

1 March 2003

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Nature Reviews Molecular Cell Biology

6 August 2017

published in

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6 August 2017

volume

4

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6 August 2017

issue

3

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6 August 2017

page(s)

213-224

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Positional information and the spatial pattern of cellular differentiation

6 August 2017

cites work

1 reference

Morphogens, compartments, and pattern: lessons from drosophila?

21 January 2018

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Secreted int-1 protein is associated with the cell surface

21 January 2018

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Cholesterol modification of hedgehog signaling proteins in animal development

21 January 2018

1 reference

Identification of a palmitic acid-modified form of human Sonic hedgehog

21 January 2018

1 reference

Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.

21 January 2018

1 reference

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

21 January 2018

1 reference

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

21 January 2018

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The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking

21 January 2018

1 reference

The bride of sevenless and sevenless interaction: internalization of a transmembrane ligand

21 January 2018

1 reference

Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development

21 January 2018

1 reference

Argosomes: a potential vehicle for the spread of morphogens through epithelia

21 January 2018

1 reference

The biogenesis and functions of exosomes

21 January 2018

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Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes

21 January 2018

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Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

21 January 2018

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Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes

21 January 2018

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The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

21 January 2018

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Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

21 January 2018

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Gradient formation of the TGF-beta homolog Dpp.

21 January 2018

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Dpp gradient formation in the Drosophila wing imaginal disc

21 January 2018

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Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing.

21 January 2018

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Direct and long-range action of a DPP morphogen gradient.

21 January 2018

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Activin signalling and response to a morphogen gradient.

21 January 2018

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Do morphogen gradients arise by diffusion?

21 January 2018

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The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors

21 January 2018

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Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

21 January 2018

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Regulated endocytic routing modulates wingless signaling in Drosophila embryos.

21 January 2018

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Engrailed and hedgehog make the range of Wingless asymmetric in Drosophila embryos.

21 January 2018

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ovo/svb integrates Wingless and DER pathways to control epidermis differentiation

21 January 2018

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A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila

21 January 2018

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Adaptors for clathrin-mediated traffic

21 January 2018

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Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

21 January 2018

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The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

21 January 2018

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Clathrin adaptors really adapt

21 January 2018

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A structural explanation for the recognition of tyrosine-based endocytotic signals

21 January 2018

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Molecular architecture and functional model of the endocytic AP2 complex

21 January 2018

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Protein regulation by monoubiquitin

21 January 2018

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A new ticket for entry into budding vesicles-ubiquitin

21 January 2018

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Epidermal growth factor induces ubiquitination of Eps15.

21 January 2018

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Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

21 January 2018

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Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

21 January 2018

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Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor beta chain to late endocytic compartments

21 January 2018

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Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling

21 January 2018

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Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

21 January 2018

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Control of EGF receptor signaling by clathrin-mediated endocytosis.

21 January 2018

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Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

21 January 2018

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Phosphorylation of the epidermal growth factor receptor during internalization in A-431 cells

21 January 2018

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Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis

21 January 2018

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Signal transduction. An arresting start for MAPK.

21 January 2018

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beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

21 January 2018

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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

21 January 2018

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Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

21 January 2018

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NGF-stimulated retrograde transport of trkA in the mammalian nervous system

21 January 2018

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A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA.

21 January 2018

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Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures

21 January 2018

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Sonic hedgehog induces the segregation of patched and smoothened in endosomes

21 January 2018

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Hedgehog signaling in animal development: paradigms and principles

21 January 2018

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TGF-beta signal transduction

21 January 2018

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SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

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Structural mechanism of endosome docking by the FYVE domain

21 January 2018

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The role of phosphoinositides in membrane transport

21 January 2018

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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

21 January 2018

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Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins

21 January 2018

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Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways

21 January 2018

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Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

21 January 2018

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Hrs recruits clathrin to early endosomes

21 January 2018

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

21 January 2018

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Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

21 January 2018

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TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

21 January 2018

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The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling

21 January 2018

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Early endosomal regulation of Smad-dependent signaling in endothelial cells

21 January 2018

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Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway

21 January 2018

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The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.

21 January 2018

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Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane

21 January 2018

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A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo.

21 January 2018

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Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

21 January 2018

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Circularly permuted green fluorescent proteins engineered to sense Ca2 .

21 January 2018

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Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

21 January 2018

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Exosomes: composition, biogenesis and function

21 January 2018

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Wingless gradient formation in the Drosophila wing

31 March 2020

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

31 March 2020

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Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy

31 March 2020

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Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase

31 March 2020

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Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation

31 March 2020

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Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes

31 March 2020

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Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons

31 March 2020

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An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1053

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6 August 2017

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