A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site. (Q35075447)

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30 December 2019

title

A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site (English)

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30 December 2019

2

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30 December 2019

Guo-Qiang Feng

4

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30 December 2019

Florian Hollfelder

8

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30 December 2019

Jonathan Waltho

9

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30 December 2019

Nicholas H Williams

10

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3

Marko Golicnik

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30 December 2019

5

Andrea M Hounslow

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6

Wolfgang Bermel

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30 December 2019

author name string

Nicola J Baxter

1

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30 December 2019

G Michael Blackburn

7

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30 December 2019

language of work or name

English

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publication date

21 September 2006

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Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

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volume

103

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issue

40

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page(s)

14732-14737

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Enzymatic transition states and transition state analogues

30 December 2019

cites work

1 reference

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The structure of bovine F1-ATPase inhibited by ADP and beryllium fluoride

8 July 2018

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Analysis of the substrate specificity loop of the HAD superfamily cap domain

8 July 2018

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Thermodynamic and extrathermodynamic requirements of enzyme catalysis

8 July 2018

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A perspective on enzyme catalysis.

8 July 2018

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The biochemistry and physiology of metallic fluoride: action, mechanism, and implications

8 July 2018

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Phosphotransfer networks and cellular energetics

8 July 2018

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The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases

8 July 2018

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The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction

8 July 2018

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Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis

8 July 2018

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MgF(3)(-) as a transition state analog of phosphoryl transfer

8 July 2018

1 reference

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BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase

8 July 2018

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Femtochemistry: Atomic-Scale Dynamics of the Chemical Bond Using Ultrafast Lasers (Nobel Lecture)

8 July 2018

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pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog

8 July 2018

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

8 July 2018

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AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP

8 July 2018

1 reference

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Product formation and phosphoglucomutase activities in Lactococcus lactis: cloning and characterization of a novel phosphoglucomutase gene

8 July 2018

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Fluoride inhibition of yeast enolase: crystal structure of the enolase-Mg(2 )-F(-)-Pi complex at 2.6 A resolution

8 July 2018

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Purification and characterization of two phosphoglucomutases from Lactococcus lactis subsp. lactis and their regulation in maltose- and glucose-utilizing cells

8 July 2018

1 reference

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Metabolism of trehalose in Euglena gracilis. Beta glucose 1,6-bisphosphate, activation factor of phosphoglucomutase for beta glucose 1-phosphate.

8 July 2018

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Chemistry. Seeing is believing

8 July 2018

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Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis

21 January 2018

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Chemical confirmation of a pentavalent phosphorane in complex with beta-phosphoglucomutase

21 January 2018

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High-energy intermediate or stable transition state analogue: theoretical perspective of the active site and mechanism of beta-phosphoglucomutase

21 January 2018

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Crystallization and preliminary X-ray diffraction studies of beta-phosphoglucomutase from Lactococcus lactus

21 January 2018

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Computational study of a transition state analog of phosphoryl transfer in the Ras-RasGAP complex: AlF(x) versus MgF3-.

21 January 2018

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Inhibition of the ATPase activity of Escherichia coli ATP synthase by magnesium fluoride

21 January 2018

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Effects of domain dissection on the folding and stability of the 43 kDa protein PGK probed by NMR.

21 January 2018

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Purification and enzymatic characterization of PgcM: a beta-phosphoglucomutase and glucose-1-phosphate phosphodismutase of Bacillus subtilis

27 September 2018

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12 December 2020

Enzymatic transition states and transition state analog design

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12 December 2020

Formation constants beta(2) of calcium and magnesium fluorides at 25 degrees C

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12 December 2020

Comment on "The Pentacovalent Phosphorus Intermediate of a Phosphoryl Transfer Reaction"

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0604448103

1 reference

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30 December 2019

0 references

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30 December 2019

PubMed publication ID

16990434

1 reference