Contrasting alloreactive CD4 and CD8 T cells: there's more to it than MHC restriction (Q35072094)

6 August 2017

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title

Contrasting alloreactive CD4 and CD8 T cells: there's more to it than MHC restriction (English)

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6 August 2017

Keri L Csencsits

1

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author name string

D Keith Bishop

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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American Journal of Transplantation

6 August 2017

published in

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6 August 2017

volume

3

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6 August 2017

issue

2

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6 August 2017

page(s)

107-115

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Two gut intraepithelial CD8 lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation

6 August 2017

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Bystander activation of CD8 T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens

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Cutting edge: membrane lymphotoxin regulates CD8( ) T cell-mediated intestinal allograft rejection.

21 January 2018

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Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts.

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CD4 but not CD8 cells are essential for allorejection

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Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

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Interferon-gamma acts directly on rejecting renal allografts to prevent graft necrosis

21 January 2018

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A role for eosinophils in transplant rejection

21 January 2018

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Regulating the immune response to transplants. a role for CD4 regulatory cells?

21 January 2018

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Cytokines induce the development of functionally heterogeneous T helper cell subsets

21 January 2018

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Transcriptional regulation of Th1/Th2 polarization

21 January 2018

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

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Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

21 January 2018

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A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

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Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4( ) versus CD8( ) T cells

21 January 2018

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Interleukin-18 regulates both Th1 and Th2 responses

21 January 2018

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IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis

21 January 2018

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Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

21 January 2018

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

21 January 2018

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Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

21 January 2018

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Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

21 January 2018

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Regulation of immune responses by TGF-beta

21 January 2018

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DNA-liposome versus adenoviral mediated gene transfer of transforming growth factor beta1 in vascularized cardiac allografts: differential sensitivity of CD4 and CD8 T cells to transforming growth factor beta1.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The growth of the very large CD8 T cell clones in older mice is controlled by cytokines.

21 January 2018

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21 January 2018

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21 January 2018

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An antagonist IL-15/Fc protein prevents costimulation blockade-resistant rejection

21 January 2018

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The role of T-cell costimulatory activation pathways in transplant rejection

21 January 2018

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The future of organ and tissue transplantation: can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection?

21 January 2018

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Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

21 January 2018

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The role of TNF receptor and TNF superfamily molecules in organ transplantation

21 January 2018

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Naive CD8 T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells.

21 January 2018

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Role of CD28 for the generation and expansion of antigen-specific CD8( ) T lymphocytes during infection with Listeria monocytogenes.

21 January 2018

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Listeria monocytogenes infection overcomes the requirement for CD40 ligand in exogenous antigen presentation to CD8( ) T cells.

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8( ) T cells.

21 January 2018

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A critical role for CD40-CD40 ligand interactions in amplification of the mucosal CD8 T cell response

21 January 2018

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T cell co-stimulatory molecules other than CD28.

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Role of 4-1BB in immune responses

21 January 2018

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Human 4-1BB regulates CD28 co-stimulation to promote Th1 cell responses

21 January 2018

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4-1BB costimulatory signals preferentially induce CD8 T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Role of CD40 Ligand and CD28 in Induction and Maintenance of Antiviral CD8 Effector T Cell Responses

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Cutting Edge: Precursor Frequency Affects the Helper Dependence of Cytotoxic T Cells

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Differential Survival of Naive CD4 and CD8 T Cells

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Multiple paths for activation of naive CD8 T cells: CD4-independent help

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

CD8 T cells are capable of rejecting pancreatic islet xenografts

21 January 2018

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Immunobiology of allograft rejection in the absence of IFN-gamma: CD8 effector cells develop independently of CD4 cells and CD40-CD40 ligand interactions

21 January 2018

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The immunobiology of inductive anti-CD40L therapy in transplantation: allograft acceptance is not dependent upon the deletion of graft-reactive T cells

21 January 2018

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IL-5 and eosinophils mediate the rejection of fully histoincompatible vascularized cardiac allografts: regulatory role of alloreactive CD8( ) T lymphocytes and IFN-gamma

21 January 2018

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IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

21 January 2018

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Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival

21 January 2018

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CD40-CD40 ligand-independent activation of CD8 T cells can trigger allograft rejection

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination

21 January 2018

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Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients

21 January 2018

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https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1034/J.1600-6143.2003.00036.X

4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function

21 January 2018

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Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen

21 January 2018

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7 January 2021

Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly cells in the generation of killer activity

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Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype

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Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-Reactivity

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Coreceptors and adapter proteins in T-cell signaling

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7 January 2021

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

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Molecular biology and function of CD4 and CD8

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Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines

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Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection

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Cellular basis of skin allograft rejection: an in vivo model of immune-mediated tissue destruction

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Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

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Islet allograft survival after a single course of treatment of recipient with antibody to L3T4

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Evidence that long-term cardiac allograft survival induced by anti-CD4 monoclonal antibody does not require depletion of CD4 T cells

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7 January 2021

Asialo GM1( ) CD8( ) T cells play a critical role in costimulation blockade-resistant allograft rejection

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Acute rejection of cardiac allografts by noncytolytic CD4( ) T cell populations

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Transfusion of polarized TH2-like cell populations into SCID mouse cardiac allograft recipients results in acute allograft rejection

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7 January 2021

CD8 T cell subsets TC1 and TC2 cause different histopathologic forms of murine cardiac allograft rejection

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7 January 2021

Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejection

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7 January 2021

Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival?

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7 January 2021

Human TH1 and TH2 subsets: doubt no more

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7 January 2021

The functional role of CD8 T helper type 2 cells

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7 January 2021

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

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7 January 2021

Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo

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7 January 2021

Intragraft IL-15 transcripts are increased in human renal allograft rejection

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7 January 2021

10.1034/J.1600-6143.2003.00036.X

Identifiers

DOI

1 reference

6 August 2017

1 reference