The role of transcription factors in atrial fibrillation (Q35062042)

6 August 2017

1 reference

title

The role of transcription factors in atrial fibrillation (English)

1 reference

6 August 2017

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Mengchen Zhou

1

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6 August 2017

Yuhua Liao

series ordinal

2

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6 August 2017

Xin Tu

series ordinal

3

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6 August 2017

publication date

1 February 2015

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Journal of thoracic disease

6 August 2017

published in

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6 August 2017

volume

7

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6 August 2017

issue

2

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6 August 2017

page(s)

152-158

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Next-generation sequencing of nine atrial fibrillation candidate genes identified novel de novo mutations in patients with extreme trait of atrial fibrillation.

6 August 2017

cites work

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Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

8 July 2018

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Genetic polymorphisms in ZFHX3 are associated with atrial fibrillation in a Chinese Han population

8 July 2018

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Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation

8 July 2018

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Down-regulation of ATBF1 activates STAT3 signaling via PIAS3 in pacing-induced HL-1 atrial myocytes

8 July 2018

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Mutational spectrum of the NKX2-5 gene in patients with lone atrial fibrillation

8 July 2018

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Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells

8 July 2018

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Genetic basis of atrial fibrillation

8 July 2018

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Atrial Fibrillation associated chromosome 4q25 variants are not associated with PITX2c expression in human adult left atrial appendages

8 July 2018

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Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes

8 July 2018

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Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

8 July 2018

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Atrial fibrillation: Stroke prevention in focus

8 July 2018

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Weighted gene coexpression network analysis of human left atrial tissue identifies gene modules associated with atrial fibrillation

8 July 2018

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Prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial fibrillation

8 July 2018

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SNP rs3825214 in TBX5 is associated with lone atrial fibrillation in Chinese Han population

8 July 2018

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Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion

8 July 2018

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Personalized medicine and atrial fibrillation: will it ever happen?

8 July 2018

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Common atrial fibrillation risk alleles at 4q25 predict recurrence after catheter-based atrial fibrillation ablation

8 July 2018

1 reference

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Genetic polymorphisms confer risk of atrial fibrillation in patients with heart failure: a population-based study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

New advances in the genetic basis of atrial fibrillation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation.

8 July 2018

1 reference

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Meta-analysis identifies six new susceptibility loci for atrial fibrillation

8 July 2018

1 reference

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Association between variants on chromosome 4q25, 16q22 and 1q21 and atrial fibrillation in the Polish population

8 July 2018

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2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation

8 July 2018

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Significant association of SNP rs2106261 in the ZFHX3 gene with atrial fibrillation in a Chinese Han GeneID population

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Association between familial atrial fibrillation and risk of new-onset atrial fibrillation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

A de novo mutation in NKX2.5 associated with atrial septal defects, ventricular noncompaction, syncope and sudden death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Functional analysis of novel TBX5 T-box mutations associated with Holt-Oram syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

8 July 2018

1 reference

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Genome-wide association study of PR interval

8 July 2018

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Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Long-term outcomes in individuals with prolonged PR interval or first-degree atrioventricular block

8 July 2018

1 reference

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Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

An epidemiological study on the prevalence of atrial fibrillation in the Chinese population of mainland China

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

New risk factors for atrial fibrillation: causes of 'not-so-lone atrial fibrillation'.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Variants conferring risk of atrial fibrillation on chromosome 4q25.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

T-box genes in vertebrate development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Function follows form: cardiac conduction system defects in Nkx2-5 mutation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Inflammation as a risk factor for atrial fibrillation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

TBX5 overexpression stimulates differentiation of chamber myocardium in P19C16 embryonic carcinoma cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

KCNQ1 gain-of-function mutation in familial atrial fibrillation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus

8 July 2018

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The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Patterns of paired-related homeobox genes PRX1 and PRX2 suggest involvement in matrix modulation in the developing chick vascular system.

8 July 2018

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Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Pitx2 participates in the late phase of the pathway controlling left-right asymmetry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Specific Inhibition of Stat3 Signal Transduction by PIAS3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Angiotensin II–Induced Stimulation of Smooth Muscle α-Actin Expression by Serum Response Factor and the Homeodomain Transcription Factor MHox

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Control of skeletal muscle-specific transcription: involvement of paired homeodomain and MADS domain transcription factors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Regulation of Muscle Differentiation by the MEF2 Family of MADS Box Transcription Factors

8 July 2018

1 reference

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Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor

8 July 2018

1 reference

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MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer

8 July 2018

1 reference

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SUMOylation: a novel protein quality control modifier in the heart.

8 July 2018

1 reference

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A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Epidemiology, risk factors for stroke, and management of atrial fibrillation in China

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Rapid and stable re-entry within the pulmonary vein as a mechanism initiating paroxysmal atrial fibrillation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Impact of the distribution and structure of myocardium in the pulmonary veins for radiofrequency ablation of atrial fibrillation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Several common variants modulate heart rate, PR interval and QRS duration

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

A novel CSX/NKX2-5 mutation causes autosomal-dominant AV block: are atrial fibrillation and syncopes part of the phenotype?

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321073

Pulmonary vein variants predispose to atrial fibrillation: a case-control study using multislice contrast-enhanced computed tomography

16 November 2018

1 reference

12 December 2020

Membrane translocation of small GTPase Rac1 and activation of STAT1 and STAT3 in pacing-induced sustained atrial fibrillation

1 reference

12 December 2020

Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population

1 reference

12 December 2020

Molecular genetics of atrial fibrillation

1 reference

12 December 2020

A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation

1 reference

12 December 2020

10.3978/J.ISSN.2072-1439.2015.01.21

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference