Adenoviral vectors: systemic delivery and tumor targeting (Q35043111)

6 August 2017

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title

Adenoviral vectors: systemic delivery and tumor targeting (English)

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6 August 2017

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Nicola K Green

1

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6 August 2017

Leonard W Seymour

series ordinal

2

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6 August 2017

publication date

1 December 2002

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6 August 2017

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6 August 2017

volume

9

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6 August 2017

issue

12

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6 August 2017

page(s)

1036-1042

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Blood clearance rates of adenovirus type 5 in mice

6 August 2017

cites work

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Liver bypass significantly increases the transduction efficiency of recombinant adenoviral vectors in the lung, intestine, and kidney

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Impact of preimmunization on adenoviral vector expression and toxicity in a subcutaneous mouse cancer model

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Influence of adenoviral fiber mutations on viral encapsidation, infectivity and in vivo tropism

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Targeted gene delivery by tropism-modified adenoviral vectors

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Targeting endothelium for gene therapy via receptors up-regulated during angiogenesis and inflammation

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Selective targeting of gene transfer to vascular endothelial cells by use of peptides isolated by phage display

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Efficient adenoviral gene transfer to kidney cortical vasculature utilizing a fiber modified vector

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Fibroblast growth factor 2-retargeted adenoviral vectors exhibit a modified biolocalization pattern and display reduced toxicity relative to native adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Modification of an adenoviral vector with biologically selected peptides: a novel strategy for gene delivery to cells of choice

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Targeting the urokinase plasminogen activator receptor enhances gene transfer to human airway epithelia.

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

1 reference

7 January 2021

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Adenovirus replication-competent vectors (KD1, KD3) complement the cytotoxicity and transgene expression from replication-defective vectors (Ad-GFP, Ad-Luc)

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Recombinant adenovirus gene transfer in adults with partial ornithine transcarbamylase deficiency (OTCD).

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

NAS report under scrutiny.

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Complement activation by recombinant adenoviruses.

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer

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https://api.crossref.org/works/10.1038/SJ.CGT.7700541

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700541

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6 August 2017

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