Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells (Q35034972)

5 August 2017

title

Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells (English)

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7

Stephen Gould

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9

Zora Modrusan

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5 August 2017

Greg Plowman

12

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author name string

Weiwei Chen

1

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5 August 2017

Tracy Tang

2

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5 August 2017

Jeff Eastham-Anderson

3

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5 August 2017

Debra Dunlap

4

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Bruno Alicke

5

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Michelle Nannini

6

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5 August 2017

Robert Yauch

8

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Kelly J DuPree

10

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Walter C Darbonne

11

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5 August 2017

Frederic J de Sauvage

13

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5 August 2017

Christopher A Callahan

14

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5 August 2017

language of work or name

English

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publication date

19 May 2011

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

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volume

108

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5 August 2017

issue

23

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5 August 2017

page(s)

9589-9863

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Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy

5 August 2017

cites work

1 reference

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Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells

8 July 2018

1 reference

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Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

8 July 2018

1 reference

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

8 July 2018

1 reference

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Hedgehog signalling: emerging evidence for non-canonical pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Sonic hedgehog promotes desmoplasia in pancreatic cancer

8 July 2018

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A paracrine requirement for hedgehog signalling in cancer

8 July 2018

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Quantitative in situ hybridization of tissue microarrays

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Hedgehog signaling in murine vasculogenesis and angiogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Stromal fibroblasts in cancer initiation and progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

The biology of VEGF and its receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

8 July 2018

1 reference

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Sonic hedgehog signaling pathway in vertebrate epithelial appendage morphogenesis: perspectives in development and evolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111273

Transformation of the microvascular system during multistage tumorigenesis

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.1017945108

Sonic hedgehog protein promotes bone marrow-derived endothelial progenitor cell proliferation, migration and VEGF production via PI 3-kinase/Akt signaling pathways

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21597001

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21597001

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1017945108

1 reference

5 August 2017

0 references

1 reference

5 August 2017

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