Physiologically based pharmacokinetics and cancer risk assessment (Q35031129)

5 August 2017

title

Physiologically based pharmacokinetics and cancer risk assessment (English)

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5 August 2017

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Andersen ME

1

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5 August 2017

Krishnan K

series ordinal

2

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5 August 2017

publication date

1 January 1994

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Environmental Health Perspectives

5 August 2017

published in

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5 August 2017

volume

102 Suppl 1

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5 August 2017

page(s)

103-108

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Mutation and cancer: a model for human carcinogenesis

5 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Biologically motivated cancer risk models

8 July 2018

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Incorporation of in vitro enzyme data into the physiologically-based pharmacokinetic (PB-PK) model for methylene chloride: implications for risk assessment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Pharmacokinetics, biochemical mechanism and mutation accumulation: a comprehensive model of chemical carcinogenesis.

8 July 2018

1 reference

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Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Commentary on EPA carcinogen risk assessment guidelines

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Variability of safe dose estimates when using complicated models of the carcinogenic process. A case study: methylene chloride.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Development of a physiologically based pharmacokinetic model for risk assessment with 1,4-dioxane.

8 July 2018

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Biologically based pharmacodynamic models: tools for toxicological research and risk assessment

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Development and utilization of physiologically based pharmacokinetic models for toxicological applications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans.

8 July 2018

1 reference

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Theta, a new class of glutathione transferases purified from rat and man

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Partition coefficients of some aromatic hydrocarbons and ketones in water, blood and oil

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566886

Estimating the risk of liver cancer associated with human exposures to chloroform using physiologically based pharmacokinetic modeling

25 October 2018

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12 December 2020

Tissue weights of the rat. I. Normal values determined by dissection and chemical methods

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12 December 2020

Metabolism of dihalomethanes to carbon monoxide. I. In vivo studies

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12 December 2020

Drug metabolism in man and its relationship to that in three rodent species: monooxygenase, epoxide hydrolase, and glutathione S-transferase activities in subcellular fractions of lung and liver

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12 December 2020

Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants for two independent pathways

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12 December 2020

Identifiers

DOI

10.1289/EHP.94102S1103

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5 August 2017

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5 August 2017

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