SIX2 Effects on Wilms Tumor Biology (Q35028775)

25500091

5 August 2017

title

SIX2 Effects on Wilms Tumor Biology (English)

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5 August 2017

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2

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11 June 2020

Kenyi Saito Diaz

7

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Gregory D Ayers

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11 June 2020

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Janene Pierce

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11 June 2020

author name string

Alexis Panzer

3

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11 June 2020

Christian de Caestecker

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11 June 2020

David Neblett

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Mark de Caestecker

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11 June 2020

Harold N Lovvorn

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publication date

1 December 2014

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25500091

5 August 2017

published in

Translational Oncology

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volume

7

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issue

6

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11 June 2020

page(s)

800-811

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CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.

11 June 2020

cites work

1 reference

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Is Wilms tumor a candidate neoplasia for treatment with WNT/β-catenin pathway modulators?--A report from the renal tumors biology-driven drug development workshop

8 July 2018

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Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties

8 July 2018

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Role for compartmentalization in nephron progenitor differentiation

8 July 2018

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CITED1 expression in liver development and hepatoblastoma

8 July 2018

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Children's Oncology Group's 2013 blueprint for research: renal tumors

8 July 2018

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The stem and roots of Wilms' tumours

8 July 2018

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The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targets

8 July 2018

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The pluripotent renal stem cell regulator SIX2 is activated in renal neoplasms and influences cellular proliferation and migration

8 July 2018

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Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks

8 July 2018

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Cancer stem cells: current status and evolving complexities

8 July 2018

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SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor

8 July 2018

1 reference

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Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa

8 July 2018

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Symmetric Division Versus Asymmetric Division: A Tale of Two Coactivators

8 July 2018

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Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming

8 July 2018

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High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

8 July 2018

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Wilms tumor—a renal stem cell malignancy?

8 July 2018

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Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

8 July 2018

1 reference

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The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators

8 July 2018

1 reference

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Targeting Wnt signaling: can we safely eradicate cancer stem cells?

8 July 2018

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Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population

8 July 2018

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Characterization of a WiT49 cell line derived orthotopic model of Wilms tumor

8 July 2018

1 reference

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Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

8 July 2018

1 reference

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Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney

8 July 2018

1 reference

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A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system

8 July 2018

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Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression

8 July 2018

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Management of Wilms' tumour: current practice and future goals

8 July 2018

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Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

8 July 2018

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8 July 2018

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Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor

8 July 2018

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8 July 2018

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The prognostic significance of blastemal predominant histology in initially resected Wilms' tumors: a report from the Study Group for Pediatric Solid Tumors in the Kyushu Area, Japan.

25 October 2018

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Characteristics and outcome of stage II and III non-anaplastic Wilms' tumour treated according to the SIOP trial and study 93-01.

25 October 2018

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Resistance or sensitivity of Wilms’ tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target

25 October 2018

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25 October 2018

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Nephrogenic rests and the pathogenesis of Wilms tumor: developmental and clinical considerations

25 October 2018

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25 October 2018

Identifiers

DOI

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11 June 2020

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25500091

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