Structure and zymogen activation of caspases (Q35028526)

5 August 2017

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title

Structure and zymogen activation of caspases (English)

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5 August 2017

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Mrudula Donepudi

1

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5 August 2017

Markus G Grütter

series ordinal

2

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5 August 2017

publication date

1 December 2002

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5 August 2017

published in

Biophysical Chemistry

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5 August 2017

volume

101-102

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5 August 2017

page(s)

145-153

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Cell suicide for beginners

5 August 2017

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Suicidal tendencies: apoptotic cell death by caspase family proteinases

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Caspases: enemies within

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Apoptotic pathways: the roads to ruin

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Death receptors: signaling and modulation

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Mitochondria and apoptosis

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

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Structure and mechanism of interleukin-1 beta converting enzyme

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Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

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The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

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Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone

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The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

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The atomic-resolution structure of human caspase-8, a key activator of apoptosis

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The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

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7 January 2021

Dimer formation drives the activation of the cell death protease caspase 9

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Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme

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An induced proximity model for caspase-8 activation.

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

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7 January 2021

Catalytic properties of the caspases

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7 January 2021

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

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7 January 2021

Structural basis for the activation of human procaspase-7

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Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex

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7 January 2021

The Protein Data Bank

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

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10.1016/S0301-4622(02)00151-5

Identifiers

DOI

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5 August 2017

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