Nicotinic cholinergic modulation: galantamine as a prototype. (Q35025118)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12481195 AND SRC:MED&resulttype=core&format=json

15 December 2019

review article

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title

Nicotinic cholinergic modulation: galantamine as a prototype (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12481195 AND SRC:MED&resulttype=core&format=json

15 December 2019

author name string

Diana S Woodruff-Pak

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12481195 AND SRC:MED&resulttype=core&format=json

15 December 2019

Cynthia Lander

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12481195 AND SRC:MED&resulttype=core&format=json

15 December 2019

Hugo Geerts

series ordinal

3

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15 December 2019

publication date

1 January 2002

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CNS Neuroscience & Therapeutics

15 December 2019

published in

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15 December 2019

volume

8

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15 December 2019

issue

4

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15 December 2019

page(s)

405-426

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Neuronal nicotinic receptor deficits in Alzheimer patients with the Swedish amyloid precursor protein 670/671 mutation

15 December 2019

cites work

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Absorption, distribution, metabolism, and excretion of donepezil (Aricept) after a single oral administration to Rat

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Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution

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Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists

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Chronic treatment of old rats with donepezil or galantamine: effects on memory, hippocampal plasticity and nicotinic receptors

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Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors

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Nicotinic modulation in an animal model of a form of associative learning impaired in Alzheimer's disease

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Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease

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Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs

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beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice.

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Galantamine: Effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning

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Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity

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Nicotinic treatment of Alzheimer's disease

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Nootropic drug modulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons

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Nicotine enhances latent inhibition and ameliorates ethanol-induced deficits in latent inhibition

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Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR

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12 December 2020

beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons

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12 December 2020

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

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Accurate prediction of the bound conformation of galanthamine in the active site of Torpedo californica acetylcholinesterase using molecular docking

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12 December 2020

Dual action of n-alcohols on neuronal nicotinic acetylcholine receptors

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12 December 2020

Ultrastructural distribution of the alpha7 nicotinic acetylcholine receptor subunit in rat hippocampus.

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12 December 2020

The metabolism and excretion of galantamine in rats, dogs, and humans

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12 December 2020

The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system

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12 December 2020

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

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Galantamine--a novel cholinergic drug with a unique dual mode of action for the treatment of patients with Alzheimer's disease

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

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12 December 2020

Nicotinic systems and cognitive function

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12 December 2020

Cholinesterase inhibition by galanthamine and lycoramine

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12 December 2020

The alpha 5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

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12 December 2020

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

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12 December 2020

The Nicotinic Acetylcholine Receptor Gene Family: Structure of Nicotinic Receptors from Muscle and Neurons and Neuronal α-Bungarotoxin-Binding Proteins

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A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

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12 December 2020

Inhibition of acetylcholinesterase activity in human brain tissue and erythrocytes by galanthamine, physostigmine and tacrine

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12 December 2020

Disruption of classical conditioning in patients with Alzheimer's disease

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12 December 2020

Cholinergic influence on memory facilitation induced by angiotensin II in rats

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12 December 2020

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

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12 December 2020

Eyeblink conditioning discriminates Alzheimer's patients from non-demented aged

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12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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12 December 2020

Effects of different doses of galanthamine, a long-acting acetylcholinesterase inhibitor, on memory in mice.

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12 December 2020

Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo.

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12 December 2020

Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

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12 December 2020

Galanthamine, an acetylcholinesterase inhibitor: a time course of the effects on performance and neurochemical parameters in mice

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12 December 2020

A long-acting cholinesterase inhibitor reverses spatial memory deficits in mice.

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12 December 2020

Role of M- and N-cholinergic systems in the recovery of motor functions after ablation of the motor zones of the cat cerebral cortex

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12 December 2020

The neurobiology of learning and memory.

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12 December 2020

Isolation and structure of a hoplonemertine toxin

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12 December 2020

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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12 December 2020

Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response. I. The hippocampus

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12 December 2020

Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors

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12 December 2020

Physostigmine, galanthamine and codeine act as ‘noncompetitive nicotinic receptor agonists’ on clonal rat pheochromocytoma cells

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12 December 2020

Neuronal Nicotinic Receptor Subtypes

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12 December 2020

Arachidonic acid as a possible negative feedback inhibitor of nicotinic acetylcholine receptors on neurons.

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12 December 2020

Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons.

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12 December 2020

BCL-2 blocks glutamate toxicity in neural cell lines

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12 December 2020

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

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12 December 2020

Physostigmine and galanthamine: probes for a novel binding site on the alpha 4 beta 2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells

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12 December 2020

Monoclonal antibodies FK1 and WF6 define two neighboring ligand binding sites on Torpedo acetylcholine receptor alpha-polypeptide

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12 December 2020

Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner

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12 December 2020

D-cycloserine attenuates scopolamine-induced learning and memory deficits in rats

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12 December 2020

Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons.

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12 December 2020

Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands

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12 December 2020

The pharmacology of galanthamine and its analogues

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12 December 2020

Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine.

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12 December 2020

Eyeblink classical conditioning in Alzheimer's disease and cerebrovascular dementia.

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12 December 2020

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12 December 2020

Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity.

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12 December 2020

Potentiation and Inhibition of Neuronal Nicotinic Receptors by Atropine: Competitive and Noncompetitive Effects

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12 December 2020

Nicotinic acetylcholine receptors in health and disease

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12 December 2020

Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery

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12 December 2020

β-Amyloid peptides as direct cholinergic neuromodulators: a missing link?

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12 December 2020

Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity.

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12 December 2020

Neuromodulatory control of hippocampal function: towards a model of Alzheimer's disease

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12 December 2020

Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons.

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12 December 2020

Galantamine: effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning

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12 December 2020

10.1111/J.1527-3458.2002.TB00237.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12481195 AND SRC:MED&resulttype=core&format=json

15 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12481195 AND SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

12481195

1 reference