The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6. (Q35023922)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622905 AND SRC:MED&resulttype=core&format=json

28 February 2020

title

The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6 (English)

1 reference

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28 February 2020

main subject

metastatic breast cancer

1 reference

1

1 reference

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28 February 2020

Pete E Pascuzzi

3

1 reference

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28 February 2020

author name string

Whitney K Williams

2

1 reference

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28 February 2020

Nikolas G Balanis

4

1 reference

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28 February 2020

Barbara J Schiemann

5

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28 February 2020

Cathleen R Carlin

6

1 reference

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28 February 2020

William P Schiemann

7

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28 February 2020

publication date

1 January 2015

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28 February 2020

1 reference

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28 February 2020

volume

17

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28 February 2020

issue

1

1 reference

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28 February 2020

page(s)

124-133

1 reference

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Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers.

28 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Comprehensive molecular portraits of human breast tumours

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

CD95 death receptor and epidermal growth factor receptor (EGFR) in liver cell apoptosis and regeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Loss of Human Epidermal Growth Factor Receptor 2 (HER2) Expression in Metastatic Sites of HER2-Overexpressing Primary Breast Tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Cellular localization of the activated EGFR determines its effect on cell growth in MDA-MB-468 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Use of immunohistochemical markers can refine prognosis in triple negative breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Evidence that MIG-6 is a tumor-suppressor gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

X chromosomal abnormalities in basal-like human breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Gene 33 inhibits apoptosis of breast cancer cells and increases poly(ADP-ribose) polymerase expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Mig-6 is a negative regulator of the epidermal growth factor receptor signal

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Analysis of breast cancer related gene expression using natural splines and the Cox proportional hazard model to identify prognostic associations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Efficacy and safety of erlotinib in patients with locally advanced or metastatic breast cancer

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

Epidermal growth factor-mediated apoptosis of MDA-MB-468 human breast cancer cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309683

cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25622905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25622905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ixabepilone Alone or With Cetuximab as First-Line Treatment for Advanced/Metastatic Triple-Negative Breast Cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25622905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEO.2014.11.009

1 reference

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28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622905 AND SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

25622905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622905 AND SRC:MED&resulttype=core&format=json