E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis (Q35015916)

5 August 2017

title

E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis (English)

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5 August 2017

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M Lizé

1

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Matthias Dobbelstein

object named as

M Dobbelstein

series ordinal

3

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author name string

S Pilarski

series ordinal

2

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5 August 2017

publication date

4 December 2009

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Cell Death & Differentiation

5 August 2017

published in

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5 August 2017

volume

17

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5 August 2017

issue

3

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5 August 2017

page(s)

452-458

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Immunofluorescence-based screening identifies germ cell associated microRNA 302 as an antagonist to p63 expression

5 August 2017

cites work

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Life and death decisions by E2F-1.

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E2F - at the crossroads of life and death

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

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Role of the p53-homologue p73 in E2F1-induced apoptosis

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p14ARF links the tumour suppressors RB and p53.

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Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

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p53 and E2f: partners in life and death

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Biological principles of microRNA-mediated regulation: shared themes amid diversity

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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

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Impaired microRNA processing enhances cellular transformation and tumorigenesis

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Causes and consequences of microRNA dysregulation in cancer

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p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest

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Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215.

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7 January 2021

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

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7 January 2021

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

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7 January 2021

A microRNA component of the p53 tumour suppressor network

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The miR-34 family in cancer and apoptosis

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Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

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7 January 2021

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

1 reference

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7 January 2021

miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression

1 reference

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7 January 2021

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

1 reference

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7 January 2021

An E2F/miR-20a autoregulatory feedback loop.

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7 January 2021

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

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Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling

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E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

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7 January 2021

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

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7 January 2021

A mammalian microRNA expression atlas based on small RNA library sequencing

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7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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7 January 2021

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

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7 January 2021

miR-34a repression of SIRT1 regulates apoptosis

1 reference

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7 January 2021

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

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7 January 2021

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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7 January 2021

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

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7 January 2021

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

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Cdc20: a WD40 activator for a cell cycle degradation machine

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E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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7 January 2021

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

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7 January 2021

Identifiers

DOI

10.1038/CDD.2009.188

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release_wr7phivrdjbrxcituxkisz5zsi

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wr7phivrdjbrxcituxkisz5zsi

24 November 2022

mapped directly with Wikidata item

1 reference