Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms (Q35009210)

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English	Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms (English)

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Europe PubMed Central

PubMed publication ID

5 August 2017

episodic memory

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author name string

Nagi Idris

1

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Europe PubMed Central

PubMed publication ID

5 August 2017

Jo Neill

2

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Europe PubMed Central

PubMed publication ID

5 August 2017

Ben Grayson

3

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Europe PubMed Central

PubMed publication ID

5 August 2017

Benny Bang-Andersen

4

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Europe PubMed Central

PubMed publication ID

5 August 2017

Louise M Witten

5

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Europe PubMed Central

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5 August 2017

Lise Tøttrup Brennum

6

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Europe PubMed Central

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5 August 2017

Jørn Arnt

7

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Europe PubMed Central

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5 August 2017

publication date

23 October 2009

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5 August 2017

Psychopharmacology

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5 August 2017

208

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Europe PubMed Central

PubMed publication ID

5 August 2017

1

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Europe PubMed Central

PubMed publication ID

5 August 2017

23-36

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Europe PubMed Central

PubMed publication ID

5 August 2017

What are the functional consequences of neurocognitive deficits in schizophrenia?

1 reference

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The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: a review and meta-analysis

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The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia

1 reference

https://api.crossref.org/works/10.1007/S00213-009-1702-5

21 January 2018

Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia. Sertindole Study Group

1 reference

https://api.crossref.org/works/10.1007/S00213-009-1702-5

21 January 2018

Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

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[3H]GBR 12935 binding in vivo in mouse brain: labelling of a piperazine acceptor site

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https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

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Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat--a back translational study

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https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

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Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

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Investigation of the effects of lamotrigine and clozapine in improving reversal-learning impairments induced by acute phencyclidine and D-amphetamine in the rat.

1 reference

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A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats

1 reference

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Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat.

1 reference

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12 December 2020

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Clozapine but not haloperidol treatment reverses sub-chronic phencyclidine-induced disruption of conditional discrimination performance

1 reference

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Sertindole (Serdolect): preclinical and clinical findings of a new atypical antipsychotic

1 reference

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12 December 2020

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The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus

1 reference

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12 December 2020

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A double-blind, controlled study of sertindole versus risperidone in the treatment of moderate-to-severe schizophrenia

1 reference

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The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine efflux in the prefrontal cortex of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

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Measurement of protein using bicinchoninic acid

1 reference

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12 December 2020

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F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms.

1 reference

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Improvement in cognitive function following a switch to ziprasidone from conventional antipsychotics, olanzapine, or risperidone in outpatients with schizophrenia

1 reference

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The acute effect of sertindole on brain 5-HT2, D2 and ?1 receptors (ex vivo radioreceptor binding studies)

1 reference

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Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors

1 reference

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Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia

1 reference

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Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder

1 reference

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Subchronic Phencyclidine Administration Reduces Mesoprefrontal Dopamine Utilization and Impairs Prefrontal Cortical-Dependent Cognition in the Rat

1 reference

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Impaired recognition memory in rats after damage to the hippocampus.

1 reference

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Do Novel Antipsychotics Have Similar Pharmacological Characteristics? A Review of the Evidence

1 reference

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Low striatal and extra-striatal D2 receptor occupancy during treatment with the atypical antipsychotic sertindole

1 reference

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The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents.

1 reference

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12 December 2020

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D(1)-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia.

1 reference

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12 December 2020

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5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease

1 reference

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Executive function in schizophrenia: what impact do antipsychotics have?

1 reference

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12 December 2020

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SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

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Influence of gender on working and spatial memory in the novel object recognition task in the rat.

1 reference

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12 December 2020

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Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the glycine transporter-1 inhibitor NFPS and D-serine.

1 reference

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Dopamine, the prefrontal cortex and schizophrenia

1 reference

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Effect of alpha(1)-adrenergic antagonist prazosin on behavioral alterations induced by MK-801 in a spatial memory task in Long-Evans rats.

1 reference

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Prefrontal DA Transmission at D1 Receptors and the Pathology of Schizophrenia

1 reference

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Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial

1 reference

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Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat.

1 reference

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Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia.

1 reference

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Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy

1 reference

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Efficacy of antipsychotics to reverse phencyclidine-induced social interaction deficits in female rats--a preliminary investigation

1 reference

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Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1).

1 reference

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1 reference

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12 December 2020

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Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

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The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D1, D2, D3, 5HT2A and muscarinic receptors

1 reference

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based on heuristic

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5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

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Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved.

1 reference

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Olanzapine (Zyprexa):characteristics of a new antipsychotic

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The atypical antipsychotic ziprasidone, but not haloperidol, improves phencyclidine-induced cognitive deficits in a reversal learning task in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-equipotent doses partly explain differences among antipsychotics - implications of PET studies

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Course of recovery of cognitive impairment in patients with schizophrenia: a randomised double-blind study comparing sertindole and haloperidol.

1 reference

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12 December 2020

based on heuristic

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Neurocognitive and social functioning in schizophrenia and other diagnoses

1 reference

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12 December 2020

based on heuristic

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Insight and neurocognition in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

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The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

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Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

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based on heuristic

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Effects of repeated treatment of phencyclidine on cognition and gene expression in C57BL/6 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19851757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S00213-009-1702-5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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