GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary. (Q35001269)

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English	GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.	scientific article

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27 January 2020

GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary (English)

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27 January 2020

G protein-coupled receptor

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steroid biosynthetic process

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Lisa M Niswander

3

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27 January 2020

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Liliana Carbajal

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27 January 2020

Anindita Biswas

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27 January 2020

Hen Prizant

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27 January 2020

Stephen R Hammes

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27 January 2020

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31 March 2011

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27 January 2020

Molecular Endocrinology

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27 January 2020

25

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27 January 2020

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27 January 2020

1055-1065

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27 January 2020

Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells

1 reference

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8 July 2018

Granulosa cell-specific androgen receptors are critical regulators of ovarian development and function.

1 reference

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8 July 2018

Inhibition of matrix metalloproteinase-2 by PARP inhibitors

1 reference

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beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling.

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Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells

1 reference

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8 July 2018

Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity.

1 reference

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8 July 2018

Cross-talk between G protein-coupled and epidermal growth factor receptors regulates gonadotropin-mediated steroidogenesis in Leydig cells

1 reference

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8 July 2018

The luteinizing hormone receptor-activated extracellularly regulated kinase-1/2 cascade stimulates epiregulin release from granulosa cells

1 reference

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Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway

1 reference

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8 July 2018

A co-culture system reveals the involvement of intercellular pathways as mediators of the lutropin receptor (LHR)-stimulated ERK1/2 phosphorylation in Leydig cells

1 reference

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8 July 2018

Cell physiology of cAMP sensor Epac

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8 July 2018

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1 reference

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8 July 2018

Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling

1 reference

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8 July 2018

Epidermal growth factor receptor signaling is required for normal ovarian steroidogenesis and oocyte maturation

1 reference

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1 reference

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8 July 2018

Role of the epidermal growth factor network in ovarian follicles.

1 reference

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8 July 2018

A steroidogenic cell line with differentiation potential from mouse granulosa cells, transfected with Ad4BP and SV40 large T antigen genes

1 reference

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8 July 2018

Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

8 July 2018

Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

8 July 2018

Epidermal growth factor family members: endogenous mediators of the ovulatory response

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Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

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The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

8 July 2018

Regulation of gonadotropin secretion: implications for polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

8 July 2018

Multiple signal transduction pathways regulate ovarian steroidogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

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Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome

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8 July 2018

The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

8 July 2018

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100602

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8 July 2018

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

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8 July 2018

Hypothalamic-pituitary dysfunction in polycystic ovarian disease.

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8 July 2018

Epidermal growth factor activates steroid biosynthesis in cultured Leydig tumor cells without affecting the levels of cAMP and potentiates the activation of steroid biosynthesis by choriogonadotropin and cAMP.

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12 December 2020

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Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2 mobilization in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454403

12 December 2020

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27 January 2020

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27 January 2020

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27 January 2020

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