A randomized, phase II study of the anti-insulin-like growth factor receptor type 1 (IGF-1R) monoclonal antibody robatumumab (SCH 717454) in patients with advanced colorectal cancer (Q35000503)

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English	A randomized, phase II study of the anti-insulin-like growth factor receptor type 1 (IGF-1R) monoclonal antibody robatumumab (SCH 717454) in patients with advanced colorectal cancer	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

A randomized, phase II study of the anti-insulin-like growth factor receptor type 1 (IGF-1R) monoclonal antibody robatumumab (SCH 717454) in patients with advanced colorectal cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

Heinz-Josef Lenz

2

object named as

Heinz-Josef Lenz

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Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Edward H Lin

1

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Europe PubMed Central

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5 August 2017

Mansoor N Saleh

3

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Europe PubMed Central

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5 August 2017

Mary J Mackenzie

4

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5 August 2017

James A Knost

5

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Europe PubMed Central

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5 August 2017

Kumudu Pathiraja

6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ronald B Langdon

7

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5 August 2017

Siu-Long Yao

8

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5 August 2017

Brian D Lu

9

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5 August 2017

language of work or name

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publication date

6 June 2014

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5 August 2017

Cancer Medicine

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5 August 2017

3

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Europe PubMed Central

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5 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

988-997

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Comprehensive molecular characterization of human colon and rectal cancer

1 reference

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8 July 2018

Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors

1 reference

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8 July 2018

A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors

1 reference

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8 July 2018

The insulin and insulin-like growth factor receptor family in neoplasia: an update

1 reference

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8 July 2018

Randomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

A fully human insulin-like growth factor-I receptor antibody SCH 717454 (Robatumumab) has antitumor activity as a single agent and in combination with cytotoxics in pediatric tumor xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Insulin and insulin-like growth factor signalling in neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Insulin-like growth factor receptor as a therapeutic target in head and neck cancer

1 reference

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8 July 2018

Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

8 July 2018

High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients.

1 reference

https://api.crossref.org/works/10.1002/CAM4.263

21 January 2018

IGF-1R, IGF-1 and IGF-2 expression as potential prognostic and predictive markers in colorectal-cancer

1 reference

https://api.crossref.org/works/10.1002/CAM4.263

21 January 2018

Plasma insulin-like growth factor-binding protein-2 levels as diagnostic and prognostic biomarker of colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002/CAM4.263

21 January 2018

Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?

1 reference

https://api.crossref.org/works/10.1002/CAM4.263

21 January 2018

Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer.

1 reference

https://api.crossref.org/works/10.1002/CAM4.263

21 January 2018

18F-FDG PET is an early predictor of pathologic tumor response to preoperative radiochemotherapy in locally advanced rectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

26 October 2018

Coexpression of the IGF-IR, EGFR and HER-2 is common in colorectal cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303167

26 October 2018

Expression of insulin-like growth factor-1 receptor in human colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24905030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal expression and structural modification of the insulin-like growth-factor-II gene in human colorectal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24905030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninvasive monitoring of tumor metabolism using fluorodeoxyglucose and positron emission tomography in colorectal cancer liver metastases: correlation with tumor response to fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/24905030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible paracrine mechanism of insulin-like growth factor-2 in the development of liver metastases from colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24905030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Additional value of whole-body positron emission tomography with fluorine-18-2-fluoro-2-deoxy-D-glucose in recurrent colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24905030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma insulin-like growth factor I is inversely associated with colorectal adenoma recurrence: a novel hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24905030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/CAM4.263

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

0 references

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