Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. (Q34997280)

5 August 2017

title

Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. (English)

1 reference

5 August 2017

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1

Jane C Deng

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5 August 2017

6

Richard A Flavell

1 reference

5 August 2017

Genhong Cheng

2

1 reference

5 August 2017

Michael W Newstead

3

1 reference

5 August 2017

Xianying Zeng

4

1 reference

5 August 2017

Koichi Kobayashi

5

1 reference

5 August 2017

Theodore J Standiford

7

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5 August 2017

language of work or name

English

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publication date

17 August 2006

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Journal of Clinical Investigation

5 August 2017

published in

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5 August 2017

volume

116

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5 August 2017

issue

9

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5 August 2017

page(s)

2532-2542

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Interferon-inducible protein 10, but not monokine induced by gamma interferon, promotes protective type 1 immunity in murine Klebsiella pneumoniae pneumonia

5 August 2017

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Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages

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Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein

8 July 2018

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Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Transient transgenic expression of gamma interferon promotes Legionella pneumophila clearance in immunocompetent hosts

8 July 2018

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Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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CXC chemokine receptor CXCR2 is essential for protective innate host response in murine Pseudomonas aeruginosa pneumonia

8 July 2018

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Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells

8 July 2018

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Lps(d)/Ran of endotoxin-resistant C3H/HeJ mice is defective in mediating lipopolysaccharide endotoxin responses

8 July 2018

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The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

8 July 2018

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IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

8 July 2018

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8 July 2018

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Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival

8 July 2018

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8 July 2018

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Monocyte deactivation--rationale for a new therapeutic strategy in sepsis

8 July 2018

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Balance of inflammatory cytokines related to severity and mortality of murine sepsis.

8 July 2018

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8 July 2018

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Tolerance to endotoxin-induced expression of the interleukin-1 beta gene in blood neutrophils of humans with the sepsis syndrome

8 July 2018

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Role of Ca2 in prostaglandin E2-induced T-lymphocyte proliferative suppression in sepsis.

8 July 2018

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Alveolar macrophage function in a canine model of endotoxin-induced lung injury.

8 July 2018

1 reference

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Dysregulation of in vitro cytokine production by monocytes during sepsis

8 July 2018

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Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock.

8 July 2018

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SHIP represses the generation of alternatively activated macrophages

26 October 2018

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Interleukin 13 and inflammatory markers in human sepsis

26 October 2018

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NF-kappaB expression in mononuclear cells of patients with sepsis resembles that observed in lipopolysaccharide tolerance

26 October 2018

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Intrapulmonary tumor necrosis factor gene therapy increases bacterial clearance and survival in murine gram-negative pneumonia

26 October 2018

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Lung-specific transgenic expression of KC enhances resistance to Klebsiella pneumoniae in mice.

26 October 2018

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IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.

26 October 2018

1 reference

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Immunosuppression after endotoxin shock: the result of multiple anti-inflammatory factors

26 October 2018

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Elevated levels of circulating transforming growth factor-beta 1 in patients with the sepsis syndrome

26 October 2018

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Endotoxin-induced suppression of lung host defenses

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SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

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12 December 2020

SOCS-1 participates in negative regulation of LPS responses

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12 December 2020

Defective Phagocytosis and Clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow Transplantation

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12 December 2020

LPS-Induced Upregulation of SHIP Is Essential for Endotoxin Tolerance

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Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits

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Alterations in function and phenotype of monocytes from patients with septic disease--predictive value and new therapeutic strategies

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Reduced alveolar macrophage production of tumor necrosis factor during sepsis in mice and men

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12 December 2020

Decreased production of nitric oxide by human neutrophils during septic multiple organ dysfunction syndrome. Comparison with endotoxin and cytokine effects on normal cells

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Monocyte deactivation in septic patients: restoration by IFN-gamma treatment

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12 December 2020

IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense

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12 December 2020

Plasma catecholamines during E. coli bacteremia in conscious rats

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Identifiers

DOI

10.1172/JCI28054

1 reference

5 August 2017

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5 August 2017

1 reference