Tau and axonopathy in neurodegenerative disorders (Q34995112)

5 August 2017

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title

Tau and axonopathy in neurodegenerative disorders (English)

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5 August 2017

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3

John Q Trojanowski

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5 August 2017

Makoto Higuchi

1

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5 August 2017

Virginia M Y Lee

series ordinal

2

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5 August 2017

publication date

1 January 2002

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5 August 2017

published in

NeuroMolecular Medicine

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5 August 2017

volume

2

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5 August 2017

issue

2

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5 August 2017

page(s)

131-150

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Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy

5 August 2017

cites work

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Correlations between mental state and quantitative neuropathology in the Vienna Longitudinal Study on Dementia.

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Amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam: quantitative neuropathology, immunohistochemical analysis of neuronal vulnerability, and comparison with related neurodegenerative disorders

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Formation of compact myelin is required for maturation of the axonal cytoskeleton

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12 December 2020

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

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12 December 2020

Neurofibrillary tangles in Alzheimer's disease and progressive supranuclear palsy: antigenic similarities and differences. Microtubule-associated protein tau antigenicity is prominent in all types of tangles.

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12 December 2020

Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments

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12 December 2020

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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12 December 2020

Cytoskeletal pathology in non-Alzheimer degenerative dementia: new lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration.

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12 December 2020

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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12 December 2020

Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons.

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12 December 2020

Astrocytic plaques and tufts of abnormal fibers do not coexist in corticobasal degeneration and progressive supranuclear palsy

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12 December 2020

A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies

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12 December 2020

Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy

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12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 December 2020

Pick's disease: a modern approach.

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12 December 2020

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

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12 December 2020

Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2.

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12 December 2020

Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations

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12 December 2020

Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.

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12 December 2020

Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.

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12 December 2020

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

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12 December 2020

The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons.

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12 December 2020

Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices

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12 December 2020

Abnormal Tau proteins in progressive supranuclear palsy. Similarities and differences with the neurofibrillary degeneration of the Alzheimer type.

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12 December 2020

Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

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12 December 2020

Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice.

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12 December 2020

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

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12 December 2020

p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

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12 December 2020

Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue

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12 December 2020

Polarity of axoplasmic microtubules in the olfactory nerve of the frog

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12 December 2020

The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.

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12 December 2020

Light and electron microscopic studies of the distribution of microtubule-associated protein 2 in rat brain: a difference between dendritic and axonal cytoskeletons

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12 December 2020

Corticonigral degeneration with neuronal achromasia and basal neurofibrillary tangles

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12 December 2020

The microtubule binding domain of tau protein.

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12 December 2020

Lithium Reduces Tau Phosphorylation by Inhibition of Glycogen Synthase Kinase-3

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12 December 2020

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

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12 December 2020

A novel mutation at position 12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto)

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12 December 2020

Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease

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12 December 2020

Altered microtubule organization in small-calibre axons of mice lacking tau protein

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12 December 2020

Neurofibrillary tangles in Niemann-Pick disease type C

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12 December 2020

Phosphorylation affects the ability of tau protein to promote microtubule assembly.

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12 December 2020

Developmentally regulated expression of specific tau sequences

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12 December 2020

Argyrophilic grains: characteristic pathology of cerebral cortex in cases of adult onset dementia without Alzheimer changes

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12 December 2020

Three distinct axonal transport rates for tau, tubulin, and other microtubule-associated proteins: evidence for dynamic interactions of tau with microtubules in vivo

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12 December 2020

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

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12 December 2020

Spinal cord neurofibrillary tangles of Guamanian amyotrophic lateral sclerosis and parkinsonism-dementia complex: an immunohistochemical study

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12 December 2020

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

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12 December 2020

Neurofibrillary tangles in progressive supranuclear palsy contain the same tau epitopes identified in Alzheimer's disease PHFtau.

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12 December 2020

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

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12 December 2020

Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation

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12 December 2020

Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells

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12 December 2020

Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites.

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12 December 2020

Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes

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12 December 2020

Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration

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12 December 2020

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

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12 December 2020

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state

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12 December 2020

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

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12 December 2020

Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau

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12 December 2020

Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase-2A

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12 December 2020

Corticobasal degeneration: etiopathological significance of the cytoskeletal alterations

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12 December 2020

Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

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12 December 2020

Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity

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12 December 2020

High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands

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12 December 2020

PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus

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12 December 2020

Association of measles virus with neurofibrillary tangles in subacute sclerosing panencephalitis: a combined in situ hybridization and immunocytochemical investigation

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12 December 2020

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

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12 December 2020

Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease.

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12 December 2020

Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein

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12 December 2020

Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes

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12 December 2020

Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy).

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12 December 2020

Immunocytochemical and ultrastructural studies of Pick's disease

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12 December 2020

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

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12 December 2020

Polarity orientation of axonal microtubules

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12 December 2020

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes

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12 December 2020

Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus

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12 December 2020

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

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12 December 2020

Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease

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12 December 2020

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

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12 December 2020

Neuronal and glial tau-positive inclusions in diverse neurologic diseases share common phosphorylation characteristics

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12 December 2020

A distinct familial presenile dementia with a novel missense mutation in the tau gene

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12 December 2020

Staging of Alzheimer's disease-related neurofibrillary changes

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12 December 2020

Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice

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12 December 2020

Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells

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12 December 2020

The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs

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12 December 2020

RNA sequestration to pathological lesions of neurodegenerative diseases.

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12 December 2020

Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: expansion of the disease phenotype caused by tau gene mutations.

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12 December 2020

FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10

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12 December 2020

Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

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12 December 2020

Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation

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12 December 2020

Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome

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12 December 2020

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

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12 December 2020

Distribution of phosphate-independent MAP2 epitopes revealed with monoclonal antibodies in microwave-denatured human nervous system tissues

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12 December 2020

Identification of phosphorylation sites in PHF-TAU from patients with Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex.

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12 December 2020

The distribution of tau in the mammalian central nervous system

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12 December 2020

Glial inclusions in CNS degenerative diseases.

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12 December 2020

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

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12 December 2020

Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop

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12 December 2020

Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease

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12 December 2020

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

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12 December 2020

Subcellular localization of tau mRNA in differentiating neuronal cell culture: implications for neuronal polarity.

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12 December 2020

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

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12 December 2020

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

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12 December 2020

Demonstration of neurofibrillary tangles and neuropil thread-like structures in spinal cord white matter in parkinsonism-dementia complex on Guam and in Guamanian amyotrophic lateral sclerosis

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12 December 2020

Immunocytochemical characterization of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia of Guam

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12 December 2020

Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.

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12 December 2020

Filamentous aggregates in Pick's disease, progressive supranuclear palsy, and Alzheimer's disease share antigenic determinants with microtubule-associated protein, tau.

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12 December 2020

Neuritic pathology and dementia in Alzheimer's disease

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12 December 2020

Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease

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12 December 2020

Filaments of Pick's bodies contain altered cytoskeletal elements

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12 December 2020

Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease

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12 December 2020

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

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12 December 2020

Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation

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12 December 2020

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

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12 December 2020

Neurofibrillary tangles in Niemann-Pick disease type C.

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12 December 2020

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

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12 December 2020

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

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12 December 2020

Primary structure of high molecular weight tau present in the peripheral nervous system

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12 December 2020

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

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12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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12 December 2020

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

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12 December 2020

Both adult and juvenile tau microtubule-associated proteins are axon specific in the developing and adult rat cerebellum

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12 December 2020

Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules

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12 December 2020

A protein factor essential for microtubule assembly

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12 December 2020

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

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12 December 2020

Rapid turnover of microtubule-associated protein MAP2 in the axon revealed by microinjection of biotinylated MAP2 into cultured neurons

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12 December 2020

Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence.

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12 December 2020

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

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12 December 2020

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

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12 December 2020

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

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12 December 2020

RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments

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12 December 2020

Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues.

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12 December 2020

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

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12 December 2020

Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

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12 December 2020

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

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12 December 2020

Neurofibrillary degeneration in amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam. Immunochemical characterization of tau proteins

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12 December 2020

Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments

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12 December 2020

Astrocytic straight tubules in the brain of a patient with Pick's disease

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12 December 2020

Stress-activated protein kinase/c-jun N-terminal kinase phosphorylates tau protein

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12 December 2020

Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau.

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12 December 2020

Widespread cytoskeletal pathology characterizes corticobasal degeneration

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12 December 2020

Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite

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12 December 2020

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

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12 December 2020

Lithium inhibits neurite growth and tau protein kinase I/glycogen synthase kinase-3beta-dependent phosphorylation of juvenile tau in cultured hippocampal neurons.

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12 December 2020

Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease

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12 December 2020

Fetal-type phosphorylation of the tau in paired helical filaments

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12 December 2020

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

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12 December 2020

Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Conference Participants

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12 December 2020

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

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12 December 2020

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

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12 December 2020

Tau protein kinase I converts normal tau protein into A68-like component of paired helical filaments

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12 December 2020

Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.

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12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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12 December 2020

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

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12 December 2020

Differential expression of distinct microtubule-associated proteins during brain development

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12 December 2020

Molecular dissection of the paired helical filament

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12 December 2020

Selective Destruction of Stable Microtubules and Axons by Inhibitors of Protein Serine/Threonine Phosphatases in Cultured Human Neurons (NT2N Cells)

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12 December 2020

Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein

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12 December 2020

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

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12 December 2020

Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration

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12 December 2020

New insights into genetic and molecular mechanisms of brain degeneration in tauopathies

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12 December 2020

The primary structure and heterogeneity of tau protein from mouse brain

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12 December 2020

Alzheimer's disease: a re-examination of the amyloid hypothesis

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12 December 2020

Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons

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12 December 2020

4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau

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12 December 2020

Epitopes that span the tau molecule are shared with paired helical filaments.

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12 December 2020

Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons

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12 December 2020

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12 December 2020

Progression of neurofibrillary changes and PHF-tau in end-stage Alzheimer's disease is different from plaque and cortical microglial pathology

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12 December 2020

Spinal cord neurofibrillary pathology in Alzheimer disease and Guam Parkinsonism-dementia complex

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12 December 2020

Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

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12 December 2020

Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

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12 December 2020

Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain

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12 December 2020

Neurodegenerative tauopathies

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12 December 2020

Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease

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12 December 2020

Molecular cloning and expression of glycogen synthase kinase-3/factor A

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12 December 2020

Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients.

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12 December 2020

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

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12 December 2020

Phylogenetic conservation of brain microtubule-associated proteins MAP2 and tau.

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12 December 2020

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons

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12 December 2020

Phosphorylation of tau proteins to a state like that in Alzheimer's brain is catalyzed by a calcium/calmodulin-dependent kinase and modulated by phospholipids.

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12 December 2020

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

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12 December 2020

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

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12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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12 December 2020

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

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12 December 2020

Evidence for cdk5 as a Major Activity Phosphorylating Tau Protein in Porcine Brain Extract1

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12 December 2020

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

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12 December 2020

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

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12 December 2020

Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform

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12 December 2020

Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease

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12 December 2020

Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau

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12 December 2020

Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment

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12 December 2020

Parkinsonism-dementia complex, an endemic disease on the island of Guam. II. Pathological features

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12 December 2020

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

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12 December 2020

Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

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12 December 2020

Identification of normal and pathological aging in prospectively studied nondemented elderly humans

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12 December 2020

Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice

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12 December 2020

Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau

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12 December 2020

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

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12 December 2020

Tau gene mutation K257T causes a tauopathy similar to Pick's disease

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12 December 2020

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

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12 December 2020

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias

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12 December 2020

Localization of disinhibition-dementia-parkinsonism-amyotrophy complex to 17q21-22.

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12 December 2020

Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

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12 December 2020

Signature tau neuropathology in gray and white matter of corticobasal degeneration

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12 December 2020

Distribution of tau proteins in the normal human central and peripheral nervous system

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12 December 2020

Microtubule densities and total numbers in selected axons of the crayfish abdominal nerve cord

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12 December 2020

In vivo phosphorylation sites in fetal and adult rat tau

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12 December 2020

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12 December 2020

Tau is a candidate gene for chromosome 17 frontotemporal dementia

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12 December 2020

The carboxyl third of tau is tightly bound to paired helical filaments.

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12 December 2020

Changes in microtubule stability and density in myelin-deficient shiverer mouse CNS axons

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12 December 2020

A case of adult-onset dementia with argyrophilic grains

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12 December 2020

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

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12 December 2020

Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and Ca2 influx in cultured hippocampal neurons

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12 December 2020

Tau protein binds to microtubules through a flexible array of distributed weak sites

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12 December 2020

Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons

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12 December 2020

Tau-positive glial inclusions in progressive supranuclear palsy, corticobasal degeneration and Pick's disease

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12 December 2020

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization

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12 December 2020

Identifiers

DOI

10.1385/NMM:2:2:131

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Dimensions Publication ID

5 August 2017

1031055844

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