Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling (Q34961589)

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English	Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Mechanistic target of rapamycin kinase

1 reference

GOA release 2020-03-11

Regulatory-associated protein of mTOR

1 reference

GOA release 2020-03-11

tuberous sclerosis

1 reference

based on heuristic

inferred from title

tuberous sclerosis 1

1 reference

based on heuristic

inferred from title

Kenneth J O'Riordan

object named as

Kenneth J O'Riordan

3

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object named as

Corinna Burger

6

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author name string

Wyatt B Potter

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Trina Basu

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Allison Kirchner

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Paul Rutecki

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Avtar Roopra

7

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

language of work or name

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publication date

13 August 2013

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Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

11

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Europe PubMed Central

PubMed publication ID

5 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

e1001627

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

13 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

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Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex

1 reference

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8 July 2018

Mutations causing syndromic autism define an axis of synaptic pathophysiology

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8 July 2018

Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice

1 reference

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8 July 2018

Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c

1 reference

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8 July 2018

Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function

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8 July 2018

Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy

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8 July 2018

Tuberous sclerosis complex: neurological, renal and pulmonary manifestations

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Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis

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Regulation of Eukaryotic Initiation Factor 4E (eIF4E) Phosphorylation by Mitogen-Activated Protein Kinase Occurs through Modulation of Mnk1-eIF4G Interaction

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Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

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8 July 2018

Metabolic regulation of neuronal plasticity by the energy sensor AMPK

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8 July 2018

Dysregulation of mTOR signaling in fragile X syndrome

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8 July 2018

Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy

1 reference

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8 July 2018

The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742461

8 July 2018

Rapamycin reduces seizure frequency in tuberous sclerosis complex

1 reference

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8 July 2018

IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.

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8 July 2018

The RSK family of kinases: emerging roles in cellular signalling

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8 July 2018

Reversal of learning deficits in a Tsc2 /- mouse model of tuberous sclerosis

1 reference

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8 July 2018

Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function

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8 July 2018

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742461

8 July 2018

The tuberous sclerosis complex

1 reference

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8 July 2018

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

1 reference

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8 July 2018

Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742461

8 July 2018

Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742461

8 July 2018

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742461

8 July 2018

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

1 reference

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8 July 2018

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742461

8 July 2018

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

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8 July 2018

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

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8 July 2018

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

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8 July 2018

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

1 reference

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

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8 July 2018

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

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8 July 2018

Tuberous sclerosis complex: a review of neurological aspects

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8 July 2018

A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

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8 July 2018

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

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New developments in the neurobiology of the tuberous sclerosis complex

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Role of group I metabotropic glutamate receptors in the patterning of epileptiform activities in vitro

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MR findings in tuberous sclerosis complex and correlation with seizure development and mental impairment

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8 July 2018

Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro

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8 July 2018

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

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21 January 2018

Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

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21 January 2018

Cortical tubers, cognition, and epilepsy in tuberous sclerosis

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https://api.crossref.org/works/10.1371/JOURNAL.PBIO.1001627

21 January 2018

Group I metabotropic glutamate receptor activation produces prolonged epileptiform neuronal synchronization and alters evoked population responses in the hippocampus

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21 January 2018

Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.

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21 January 2018

Persistent LTP without triggered protein synthesis

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https://api.crossref.org/works/10.1371/JOURNAL.PBIO.1001627

21 January 2018

Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression.

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Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome

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Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

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Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors

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12 December 2020

based on heuristic

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Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23966835

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

1 reference

https://pubmed.ncbi.nlm.nih.gov/23966835

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PBIO.1001627

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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