Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. (Q34938493)

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20 January 2020

title

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin (English)

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20 January 2020

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2

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20 January 2020

Michael A. Fischbach

series ordinal

5

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20 January 2020

3

Jon Clardy

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20 January 2020

4

Christopher T Walsh

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20 January 2020

author name string

Laura C Wieland Brown

series ordinal

1

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20 January 2020

language of work or name

English

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publication date

5 February 2009

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Proceedings of the National Academy of Sciences of the United States of America

20 January 2020

published in

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20 January 2020

volume

106

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20 January 2020

issue

8

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20 January 2020

page(s)

2549-2553

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The importance of the leader sequence for directing lanthionine formation in lacticin 481.

20 January 2020

cites work

1 reference

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Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin

8 July 2018

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A global assembly line for cyanobactins

8 July 2018

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Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

8 July 2018

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Discovery of a widely distributed toxin biosynthetic gene cluster

8 July 2018

1 reference

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Micrococcin, an antibacterial substance formed by a strain of Micrococcus

8 July 2018

1 reference

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From amino acids to heteroaromatics--thiopeptide antibiotics, nature's heterocyclic peptides

8 July 2018

1 reference

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Lantibiotics: peptides of diverse structure and function.

8 July 2018

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Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

8 July 2018

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Cloning and characterization of the goadsporin biosynthetic gene cluster from Streptomyces sp. TP-A0584.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

8 July 2018

Thiopeptide antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Biosynthesis of nonribosomal peptides1.

8 July 2018

1 reference

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YM-266183 and YM-266184, Novel Thiopeptide Antibiotics Produced by Bacillus cereus Isolated from a Marine Sponge. II. Structure Elucidation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Cofactor requirements and reconstitution of microcin B17 synthetase: a multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

From peptide precursors to oxazole and thiazole-containing peptide antibiotics: microcin B17 synthase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Studies on the formation of transfer ribonucleic acid-ribosome complexes. IV. Effect of antibiotics on steps of bacterial protein synthesis: some new ribosomal inhibitors of translocation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

The biosynthesis of penicillins and cephalosporins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650375

Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0950008106

Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0950008106

Biosynthesis of the modified peptide antibiotic nosiheptide in Streptomyces actuosus

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0950008106

Isolation of three new antibiotics, thiocillins I, II and III, related to micrococcin P. Studies on antibiotics from the genus Bacillus. VIII

21 January 2018

1 reference

12 December 2020

Total structure of the highly modified peptide antibiotic components of thiopeptin

1 reference

12 December 2020

The leader peptide is essential for the post-translational modification of the DNA-gyrase inhibitor microcin B17

1 reference

12 December 2020

Elaboration of an electroporation protocol for Bacillus cereus ATCC 14579

1 reference

12 December 2020

A physical map of the syringomycin and syringopeptin gene clusters localized to an approximately 145-kb DNA region of Pseudomonas syringae pv. syringae strain B301D

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0950008106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196969 AND SRC:MED&resulttype=core&format=json

20 January 2020

0 references

1 reference

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20 January 2020

PubMed publication ID

19196969

1 reference