The p53 network in lung carcinogenesis. (Q34935933)

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13 December 2019

review article

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title

The p53 network in lung carcinogenesis (English)

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13 December 2019

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2

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13 December 2019

author name string

Ana I Robles

series ordinal

1

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13 December 2019

Curtis C Harris

series ordinal

3

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13 December 2019

language of work or name

English

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publication date

1 October 2002

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13 December 2019

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13 December 2019

volume

21

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13 December 2019

issue

45

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13 December 2019

page(s)

6898-6907

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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

13 December 2019

cites work

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p14ARF links the tumour suppressors RB and p53.

21 January 2018

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Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

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Interaction of p53 with the Human Rad51 Protein

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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A p53-dependent mouse spindle checkpoint

21 January 2018

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

21 January 2018

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Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

21 January 2018

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

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Human ARF binds E2F1 and inhibits its transcriptional activity.

21 January 2018

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Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma.

21 January 2018

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

21 January 2018

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Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressor

21 January 2018

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Homologous and nonhomologous recombination resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation

21 January 2018

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The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

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Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

21 January 2018

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Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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Carcinogenic polynuclear hydrocarbons bind to macromolecules in cultured human bronchi.

21 January 2018

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Mdm2 promotes the rapid degradation of p53

21 January 2018

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Tobacco smoke carcinogens and lung cancer

21 January 2018

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14-3-3sigma is a p53-regulated inhibitor of G2/M progression

21 January 2018

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A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database

21 January 2018

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AIS is an oncogene amplified in squamous cell carcinoma

21 January 2018

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

21 January 2018

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p53 mutations in human cancers

21 January 2018

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Illegitimate Recombination Leading to Allelic Loss and Unbalanced Translocation in p53-Mutated Human Lymphoblastoid Cells

21 January 2018

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Regulation of the specific DNA binding function of p53

21 January 2018

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Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair

21 January 2018

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Invasive tumors derived from xenotransplanted, immortalized human cells after in vivo exposure to chemical carcinogens.

21 January 2018

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

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Regulation of cellular senescence by p53.

21 January 2018

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Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

21 January 2018

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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

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A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells

21 January 2018

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Regulation of p53 stability by Mdm2

21 January 2018

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p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

21 January 2018

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A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

21 January 2018

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Absence of mutations in the functional domains of the human MDM2 oncogene in non-small cell lung carcinomas.

21 January 2018

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A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

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Inactivation of p53 results in high rates of homologous recombination

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

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Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

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Regulation of the p53 tumor suppressor protein

21 January 2018

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BRCA1 regulates p53-dependent gene expression

21 January 2018

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

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21 January 2018

Why is p53 acetylated?

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p53-mediated apoptosis and genomic instability diseases

21 January 2018

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Human lung cancer and p53: the interplay between mutagenesis and selection

21 January 2018

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Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

21 January 2018

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The INK4a/ARF network in tumour suppression

21 January 2018

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p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes

21 January 2018

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Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons

21 January 2018

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p53-mediated apoptosis is attenuated in Werner syndrome cells

21 January 2018

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Role of a p53 polymorphism in the development of human papillomavirus-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p53: a frequent target for genetic abnormalities in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Two polymorphic variants of wild-type p53 differ biochemically and biologically

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

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Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners.

21 January 2018

1 reference

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The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

21 January 2018

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21 January 2018

Surfing the p53 network

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The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

21 January 2018

1 reference

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Identification of a novel p53 functional domain that is necessary for efficient growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p53 modulation of TFIIH–associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Functional interaction of p53 and BLM DNA helicase in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p53-independent functions of the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Detection of polycyclic aromatic hydrocarbon-DNA adducts in human lung

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Early age at smoking initiation and tobacco carcinogen DNA damage in the lung

21 January 2018

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Molecular genetics of small cell lung carcinoma

21 January 2018

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

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Mutational analysis of p73 and p53 in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

A role for p53 in base excision repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

Structures of benzo(a)pyrene–nucleic acid adducts formed in human and bovine bronchial explants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

The INK4a/ARF tumor suppressor: one gene--two products--two pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

Dissociation of the recombination control and the sequence-specific transactivation function of P53

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

Disparate cell types use a shared complex of PDZ proteins for polarized protein localization

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

p53 mutations in lung cancers from non-smoking atomic-bomb survivors

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205563

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205563

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12362272 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 December 2019

1006887615

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1 reference