monensin (Q3493048)

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chemical compound
  • monensic acid
  • monensin A
  • polyether antibiotic monensin
edit
Language Label Description Also known as
English
monensin
chemical compound
  • monensic acid
  • monensin A
  • polyether antibiotic monensin

Statements

chemical structure
Monensin A.svg
512 × 563; 38 KB
0 references
mass
670.429213 dalton
1 reference
stated in
PubChem
PubChem CID
441145
language of work or name
English
title
monensin (English)
retrieved
5 October 2016
chemical formula
C₃₆H₆₂O₁₁
1 reference
stated in
PubChem
PubChem CID
441145
language of work or name
English
title
monensin (English)
retrieved
20 November 2016
canonical SMILES
CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)O)OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C
1 reference
stated in
PubChem
PubChem CID
441145
language of work or name
English
title
monensin (English)
retrieved
20 November 2016
isomeric SMILES
CC[C@]1(CC[C@@H](O1)[C@@]2(CC[C@@]3(O2)C[C@@H]([C@H]([C@H](O3)[C@@H](C)[C@H]([C@H](C)C(=O)O)OC)C)O)C)[C@H]4[C@H](C[C@@H](O4)[C@@H]5[C@H](C[C@H]([C@@](O5)(CO)O)C)C)C
1 reference
stated in
PubChem
PubChem CID
441145
language of work or name
English
title
monensin (English)
retrieved
20 November 2016
found in taxon
Streptomyces cinnamonensis
27 references
stated in
Insertional Inactivation of Methylmalonyl Coenzyme A (CoA) Mutase and Isobutyryl-CoA Mutase Genes in Streptomyces cinnamonensis: Influence on Polyketide Antibiotic Biosynthesis
stated in
Role of Crotonyl Coenzyme A Reductase in Determining the Ratio of Polyketides Monensin A and Monensin B Produced byStreptomyces cinnamonensis
stated in
MeaA, a putative coenzyme B12-dependent mutase, provides methylmalonyl coenzyme A for monensin biosynthesis in Streptomyces cinnamonensis.
stated in
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization
stated in
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis
stated in
Resistance of Streptomyces cinnamonensis to butyrate and isobutyrate: production and properties of a new anti-isobutyrate (AIB) factor
stated in
Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.
stated in
High titer production of tetracenomycins by heterologous expression of the pathway in a Streptomyces cinnamonensis industrial monensin producer strain.
stated in
Enhancing macrolide production in Streptomyces by coexpressing three heterologous genes.
stated in
Vitamins as effectors of monensin production by Streptomyces cinnamonensis
stated in
Characterization of three pathway-specific regulators for high production of monensin in Streptomyces cinnamonensis.
stated in
Terrosamycins A and B, Bioactive Polyether Ionophores from Streptomyces sp. RKND004 from Prince Edward Island Sediment
stated in
2-Demethylmonensins A and B. Novel minor congeners of monensins from Streptomyces cinnamonensis
stated in
Propionate and the production of monensins in Streptomyces cinnamonensis
stated in
Biosynthesis of monensins A and B
stated in
Polyether biosynthesis. 2. Origin of the oxygen atoms of monensin A
stated in
Determination of monensins A and B in the fermentation broth ofStreptomyces cinnamonensis by high performance liquid chromatography
stated in
Biosynthesis of the polyether antibiotic monensin A: incorporation of a polyketide chain elongation intermediate
stated in
The incorporation of thymine and β-aminoisobutyrate into the polyether antibiotic, monensin-A
stated in
The biosynthesis of monensin-A: thymine, beta-aminoisobutyrate and methacrylate metabolism in Streptomyces cinnamonensis
stated in
Biosynthesis of the polyether antibiotic monensin-a: stereochemical aspects of the incorporation and metabolism of isobutyrate
stated in
Effect of precursors on biosynthesis of monensins A and B
stated in
Biosynthesis of monensins A and B: the role of isoleucine
stated in
Biosynthesis of the polyether ionophore antibiotic monensin A: assignment of the carbon-13 and proton n.m.r. spectra of monensin A by two-dimensional spectroscopy. Incorporation of oxygen-18 labelled molecular oxygen
stated in
Biosynthesis of monensin. The intramolecular rearrangement of isobutyryl-CoA to n-butyryl-CoA
stated in
Biosynthesis of monensins and 3-O-demethylmonensins in Streptomyces cinnamonensis in the presence of methylation inhibitors
stated in
Biosynthesis of the polyether antibiotic monensin-A. Results from the incorporations of labelled acetate and propionate as a probe of the carbon chain assembly processes
Streptomyces glaucescens
12 references
stated in
Insertional Inactivation of Methylmalonyl Coenzyme A (CoA) Mutase and Isobutyryl-CoA Mutase Genes in Streptomyces cinnamonensis: Influence on Polyketide Antibiotic Biosynthesis
stated in
Role of Crotonyl Coenzyme A Reductase in Determining the Ratio of Polyketides Monensin A and Monensin B Produced byStreptomyces cinnamonensis
stated in
MeaA, a putative coenzyme B12-dependent mutase, provides methylmalonyl coenzyme A for monensin biosynthesis in Streptomyces cinnamonensis.
stated in
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization
stated in
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis
stated in
Resistance of Streptomyces cinnamonensis to butyrate and isobutyrate: production and properties of a new anti-isobutyrate (AIB) factor
stated in
Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.
stated in
High titer production of tetracenomycins by heterologous expression of the pathway in a Streptomyces cinnamonensis industrial monensin producer strain.
stated in
Enhancing macrolide production in Streptomyces by coexpressing three heterologous genes.
stated in
Vitamins as effectors of monensin production by Streptomyces cinnamonensis
stated in
Characterization of three pathway-specific regulators for high production of monensin in Streptomyces cinnamonensis.
stated in
Terrosamycins A and B, Bioactive Polyether Ionophores from Streptomyces sp. RKND004 from Prince Edward Island Sediment

Identifiers

Reaxys registry number
1633130
1 reference
stated in
ChEBI
ChEBI ID
27617
language of work or name
English
title
monensin A (English)
retrieved
5 October 2016
HSDB ID
7031
1 reference
stated in
Hazardous Substances Data Bank
HSDB ID
7031
publication date
28 October 2019
title
MONENSIN (English)
retrieved
10 May 2021
E number
E714
0 references
MeSH tree code
D03.383.312.600
0 references
D02.355.291.933.500
0 references
D02.540.576.625.500
0 references
D04.345.241.654.500
0 references
D04.345.674.625.500
0 references
KEGG ID
D08228
1 reference
stated in
ChEBI
ChEBI ID
27617
language of work or name
English
title
monensin A (English)
retrieved
5 October 2016
 
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