Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate (Q34880994)

5 August 2017

title

Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate (English)

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5 August 2017

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10

Robert J Lutz

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5 August 2017

author name string

Gail D Lewis Phillips

1

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5 August 2017

Guangmin Li

2

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Debra L Dugger

3

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Lisa M Crocker

4

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Kathryn L Parsons

5

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Elaine Mai

6

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Walter A Blättler

7

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John M Lambert

8

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Ravi V J Chari

9

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5 August 2017

Wai Lee T Wong

11

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Frederic S Jacobson

12

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Hartmut Koeppen

13

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Ralph H Schwall

14

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Sara R Kenkare-Mitra

15

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Susan D Spencer

16

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Mark X Sliwkowski

17

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language of work or name

English

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publication date

1 November 2008

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5 August 2017

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volume

68

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5 August 2017

issue

22

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5 August 2017

page(s)

9280-9290

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describes a project that uses

5 August 2017

BT-474 EEI

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cites work

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Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

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Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

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Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates

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p95HER-2 predicts worse outcome in patients with HER-2-positive breast cancer

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

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Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies

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Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6.

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2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial.

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Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing.

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Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: the trastuzumab and vinorelbine or taxane study

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24 May 2022

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Lapatinib plus capecitabine for HER2-positive advanced breast cancer

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HER2-targeted therapy reduces incidence and progression of midlife mammary tumors in female murine mammary tumor virus huHER2-transgenic mice

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Pharmacokinetics and biodistribution of the antitumor immunoconjugate, cantuzumab mertansine (huC242-DM1), and its two components in mice

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24 May 2022

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Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells

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24 May 2022

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24 May 2022

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-08-1776

Identifiers

DOI

10.1158/0008-5472.CAN-08-1776

1 reference

5 August 2017

1 reference