ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells. (Q34868956)

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25 December 2019

title

ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells (English)

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7

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25 December 2019

Jonathan P. Sleeman

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Ulf Anderegg

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25 December 2019

author name string

Thea Eichenberg

2

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25 December 2019

Tanja Parthaune

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25 December 2019

Christian Haiduk

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25 December 2019

Anja Saalbach

5

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25 December 2019

Linda Milkova

6

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25 December 2019

Jens Grosche

8

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25 December 2019

Marco Averbeck

9

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25 December 2019

Carl Gebhardt

10

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25 December 2019

Verena Voelcker

11

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25 December 2019

Jan C Simon

13

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25 December 2019

language of work or name

English

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publication date

30 October 2008

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Journal of Investigative Dermatology

25 December 2019

published in

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25 December 2019

volume

129

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25 December 2019

issue

6

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25 December 2019

page(s)

1471-1482

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CD44 is the principal mediator of hyaluronic-acid-induced melanoma cell proliferation

25 December 2019

cites work

1 reference

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7 January 2021

Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid

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7 January 2021

Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects

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CD44 is the principal cell surface receptor for hyaluronate

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7 January 2021

CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor

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7 January 2021

RETRACTED: Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum

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7 January 2021

High CD44 surface expression on primary tumours of malignant melanoma correlates with increased metastatic risk and reduced survival

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7 January 2021

CD44s adhesive function spontaneous and PMA-inducible CD44 cleavage are regulated at post-translational level in cells of melanocytic lineage

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7 January 2021

Differential growth regulation in human melanoma cell lines by TIMP-1 and TIMP-2.

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The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

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7 January 2021

Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans

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Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration

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Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion

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Expression of E-cadherin, alpha- & beta-catenin, and CD44V6 and the subcellular localization of E-cadherin and CD44V6 in normal epidermis and basal cell carcinoma

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Inhibition of platelet-derived growth factor-BB-induced receptor activation and fibroblast migration by hyaluronan activation of CD44

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7 January 2021

Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.

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7 January 2021

ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.

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7 January 2021

Release of cell fragments by invading melanoma cells.

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7 January 2021

ADAMs in cancer cell proliferation and progression.

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7 January 2021

Elevated serum levels of soluble CD44 can identify a subgroup of patients with early B-cell chronic lymphocytic leukemia who are at high risk of disease progression

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7 January 2021

CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.

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7 January 2021

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

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7 January 2021

Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration.

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7 January 2021

Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca(2 ) influx and PKC activation

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https://api.crossref.org/works/10.1038/JID.2008.323

7 January 2021

Mechanism and biological significance of CD44 cleavage

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https://api.crossref.org/works/10.1038/JID.2008.323

7 January 2021

Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.

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7 January 2021

CD44: structure, function, and association with the malignant process.

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7 January 2021

High serum soluble CD44 is correlated with a poor outcome of aggressive non-Hodgkin's lymphoma

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7 January 2021

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration

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https://api.crossref.org/works/10.1038/JID.2008.323

7 January 2021

CD44: from adhesion molecules to signalling regulators

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7 January 2021

Breaking up the tie: disintegrin-like metalloproteinases as regulators of cell migration in inflammation and invasion.

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7 January 2021

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

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7 January 2021

Evaluation of the prognostic value of serum soluble CD 44 in patients with breast cancer

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7 January 2021

Antibody-induced shedding of CD44 from adherent cells is linked to the assembly of the cytoskeleton

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7 January 2021

Activation of the interferon system by short-interfering RNAs

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7 January 2021

A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

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7 January 2021

Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors

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7 January 2021

Properties of metastasizing and nonmetastasizing human melanoma cells.

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7 January 2021

A basolateral sorting signal directs ADAM10 to adherens junctions and is required for its function in cell migration

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7 January 2021

Soluble CD44 variant 6 as a prognostic indicator in patients with colorectal cancer

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7 January 2021

Serum levels of the soluble adhesion molecules in patients with malignant melanoma

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7 January 2021

Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion

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7 January 2021

CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling

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7 January 2021

Adam-9 expression and regulation in human skin melanoma and melanoma cell lines

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7 January 2021

Identifiers

DOI

10.1038/JID.2008.323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18971959 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 December 2019

1021035225

0 references

1 reference