Differential CTLA-4 expression in human CD4 versus CD8 T cells is associated with increased NFAT1 and inhibition of CD4 proliferation. (Q34824109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24173147 AND SRC:MED&resulttype=core&format=json

28 February 2020

title

Differential CTLA-4 expression in human CD4 versus CD8 T cells is associated with increased NFAT1 and inhibition of CD4 proliferation (English)

1 reference

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28 February 2020

2

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28 February 2020

author name string

D V Chan

1

1 reference

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28 February 2020

B M Aufiero

3

1 reference

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28 February 2020

A J Wilson

4

1 reference

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28 February 2020

M S Hafner

5

1 reference

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28 February 2020

Q-S Mi

6

1 reference

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28 February 2020

H K Wong

7

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28 February 2020

publication date

31 October 2013

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28 February 2020

1 reference

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28 February 2020

volume

15

1 reference

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28 February 2020

issue

1

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28 February 2020

page(s)

25-32

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CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma

28 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4: Not All Costimulation Is Stimulatory

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 blockade increases antigen-specific CD8( ) T cells in prevaccinated patients with melanoma: three cases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Single dose of anti-CTLA-4 enhances CD8 T-cell memory formation, function, and maintenance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CD4 regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

The mechanism of anti-CTLA-4 activity and the negative regulation of T-cell activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 control over Foxp3 regulatory T cell function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Immune function abnormalities in peripheral blood mononuclear cell cytokine expression differentiates stages of cutaneous T-cell lymphoma/mycosis fungoides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 dysregulation of self/tumor-reactive CD8 T-cell function is CD4 T-cell dependent.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

FOXP3 controls regulatory T cell function through cooperation with NFAT

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Interleukin-2 signals during priming are required for secondary expansion of CD8 memory T cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4 CD25 regulatory cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Principles and use of anti-CTLA4 antibody in human cancer immunotherapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4: new insights into its biological function and use in tumor immunotherapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Use of chromatin immunoprecipitation to clone novel E2F target promoters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Immunologic self-tolerance maintained by CD25( )CD4( ) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Expression and function of CTLA-4 in Th1 and Th2 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

A CTLA‐4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CD28/B7 system of T cell costimulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Regulation of CTLA-4 expression during T cell activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Enhancement of antitumor immunity by CTLA-4 blockade

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Characterization of CTLA-4 structure and expression on human T cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 can function as a negative regulator of T cell activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

A new member of the immunoglobulin superfamily--CTLA-4

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Increased expression of CTLA-4 in malignant T-cells from patients with mycosis fungoides -- cutaneous T cell lymphoma.

8 July 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Regulation of the murine Nfatc1 gene by NFATc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

High IFN-gamma production of individual CD8 T lymphocytes is controlled by CD152 (CTLA-4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Generation and function of immunosuppressive human and murine CD8 T cells by transforming growth factor-β and retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Expression of CTLA-4 (CD152) in peripheral blood T cells of children with influenza virus infection including encephalopathy in comparison with respiratory syncytial virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Differential expression of CTLA-4 among T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Impaired NFAT transcriptional activity in antigen-stimulated CD8 T cells linked to defective phosphorylation of NFAT transactivation domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2013.57

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Polymorphism of the CTLA-4 gene is associated with autoimmune hypothyroidism in the United Kingdom

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Increased total serum IgE levels in patients with asthma and promoter polymorphisms at CTLA4 and FCER1B

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA-4 and not CD28 is a susceptibility gene for thyroid autoantibody production

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4284071

Modulation of CD4 by antigenic activation

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24173147

12 December 2020

inferred from PubMed ID database lookup

Distinct pattern of IL-2 and IFN-gamma gene expression in CD4 and CD8 T cells: cytofluorometric analysis at a single cell level using non-radioactive probes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24173147

12 December 2020

inferred from PubMed ID database lookup

T cell priming enhances IL-4 gene expression by increasing nuclear factor of activated T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24173147

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/GENE.2013.57

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24173147 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 February 2020

1023991864

0 references

Fatcat ID

release_panwb7id7jelnk4bb7nmqpfb2u

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/panwb7id7jelnk4bb7nmqpfb2u

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24173147 AND SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

24173147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24173147 AND SRC:MED&resulttype=core&format=json