Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase (Q34818959)

4 August 2017

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title

Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase (English)

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4 August 2017

Clinton R Nishida

1

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4 August 2017

Giselle Knudsen

series ordinal

2

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4 August 2017

Wesley Straub

series ordinal

3

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4 August 2017

Paul R Ortiz de Montellano

series ordinal

4

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4 August 2017

language of work or name

English

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publication date

1 August 2002

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4 August 2017

published in

Drug Metabolism Reviews

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4 August 2017

volume

34

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4 August 2017

issue

3

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4 August 2017

page(s)

479-501

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Some aspects of the role of cytochrome P-450 isozymes in the N-oxidative transformation of secondary and tertiary amine compounds

4 August 2017

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21 January 2018

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Nitric oxide synthase is a cytochrome P-450 type hemoprotein

21 January 2018

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Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide

21 January 2018

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Coding nucleotide sequence of rat NADPH-cytochrome P-450 oxidoreductase cDNA and identification of flavin-binding domains

21 January 2018

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Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

21 January 2018

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Three-dimensional structure of NADPH–cytochrome P450 reductase: Prototype for FMN- and FAD-containing enzymes

21 January 2018

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Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer.

21 January 2018

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Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

21 January 2018

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Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

21 January 2018

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

21 January 2018

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Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase

21 January 2018

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Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase

21 January 2018

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Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer

21 January 2018

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Calmodulin is a subunit of nitric oxide synthase from macrophages

21 January 2018

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The catalytic pathway of cytochrome p450cam at atomic resolution

21 January 2018

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Epoxidation of olefins by cytochrome P450: Evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant

21 January 2018

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The mechanism of heme oxygenase

21 January 2018

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Oxidation of the meso-methylmesoheme regioisomers by heme oxygenase. Electronic control of the reaction regiospecificity

21 January 2018

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Oxidation of alpha-meso-formylmesoheme by heme oxygenase. Electronic control of the reaction regiospecificity

21 January 2018

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Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: deformylation with olefin formation

21 January 2018

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Mechanistic studies on aromatase and related C-C bond cleaving P-450 enzymes

21 January 2018

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Human endothelial nitric oxide synthase: expression in Escherichia coli, coexpression with calmodulin, and characterization

21 January 2018

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Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin.

21 January 2018

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Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin

21 January 2018

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Reaction of neuronal nitric-oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin.

21 January 2018

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Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase.

21 January 2018

1 reference

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Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity

21 January 2018

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https://api.crossref.org/works/10.1081/DMR-120005648

Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase

21 January 2018

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Formation of Nδ-Cyanoornithine from NG-Hydroxy-l-arginine and Hydrogen Peroxide by Neuronal Nitric Oxide Synthase: Implications for Mechanism

21 January 2018

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Transport and metabolism of agmatine in rat hepatocyte cultures

21 January 2018

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Oxidation of N(omega)-hydroxyarginine analogues by NO-synthase: the simple, non amino acid N-butyl N'-hydroxyguanidine is almost as efficient an NO precursor as N(omega)-hydroxyarginine

21 January 2018

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https://api.crossref.org/works/10.1081/DMR-120005648

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Active site topologies and cofactor-mediated conformational changes of nitric-oxide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Characterization of the reductase domain of rat neuronal nitric oxide synthase generated in the methylotrophic yeast Pichia pastoris. Calmodulin response is complete within the reductase domain itself

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Calcium Binding Sites of Calmodulin and Electron Transfer by Neuronal Nitric Oxide Synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Rapid calmodulin-dependent interdomain electron transfer in neuronal nitric-oxide synthase measured by pulse radiolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Structural domains of P450-containing monooxygenase systems

21 January 2018

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Atomic structure of ferredoxin-NADP reductase: prototype for a structurally novel flavoenzyme family

21 January 2018

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Comparison of the crystal structures of a flavodoxin in its three oxidation states at cryogenic temperatures

21 January 2018

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Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module

21 January 2018

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Structure of a cytochrome P450-redox partner electron-transfer complex

21 January 2018

1 reference

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Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Characterization of the roles of the 863-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Removal of a putative inhibitory element reduces the calcium-dependent calmodulin activation of neuronal nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Control of electron transfer in nitric-oxide synthases. Swapping of autoinhibitory elements among nitric-oxide synthase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

High reductase activity of recombinant NOS2 flavoprotein domain lacking the calmodulin binding regulatory sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

The Akt kinase signals directly to endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Regulation of neuronal nitric-oxide synthase by calmodulin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

The C terminus of mouse macrophage inducible nitric-oxide synthase attenuates electron flow through the flavin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Stoichiometric Arginine Binding in the Oxygenase Domain of Inducible Nitric Oxide Synthase Requires a Single Molecule of Tetrahydrobiopterin per Dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Formation of a Pterin Radical in the Reaction of the Heme Domain of Inducible Nitric Oxide Synthase with Oxygen†

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Intra-subunit and inter-subunit electron transfer in neuronal nitric-oxide synthase: effect of calmodulin on heterodimer catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Metabolic N-oxide formation by rabbit-liver microsomal cytochrome P-4502B4: involvement of superoxide in the NADPH-dependent N-oxygenation of N,N-dimethylaniline

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Mechanism of the acyl-carbon cleavage and related reactions catalyzed by multifunctional P-450s: studies on cytochrome P-450(17)alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Comparative Functioning of Dihydro- and Tetrahydropterins in Supporting Electron Transfer, Catalysis, and Subunit Dimerization in Inducible Nitric Oxide Synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Low-Temperature Optical Absorption Spectra Suggest a Redox Role for Tetrahydrobiopterin in Both Steps of Nitric Oxide Synthase Catalysis†

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Efficient formation of nitric oxide from selective oxidation of N-aryl N'-hydroxyguanidines by inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Calmodulin promotes dimerization of the oxygenase domain of human endothelial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Calmodulin activates intramolecular electron transfer between the two flavins of neuronal nitric oxide synthase flavin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Inducible nitric oxide synthase requires both the canonical calmodulin-binding domain and additional sequences in order to bind calmodulin and produce nitric oxide in the absence of free Ca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Electron transfer and catalytic activity of nitric oxide synthases. Chimeric constructs of the neuronal, inducible, and endothelial isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

NADPH-cytochrome P-450 oxidoreductase: flavin mononucleotide and flavin adenine dinucleotide domains evolved from different flavoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2 )/calmodulin-dependent electron transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081/DMR-120005648

21 January 2018

Identifiers

DOI

10.1081/DMR-120005648

1 reference

4 August 2017

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