Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas (Q34810518)

4 August 2017

title

Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas (English)

1 reference

4 August 2017

Jacquelyn J Roth

1

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4 August 2017

Mariarita Santi

2

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4 August 2017

Avrum N Pollock

3

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4 August 2017

Brian N Harding

4

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4 August 2017

Lucy B Rorke-Adams

5

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4 August 2017

Laura S Tooke

6

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4 August 2017

Jaclyn A Biegel

7

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4 August 2017

publication date

12 September 2014

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4 August 2017

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4 August 2017

volume

25

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4 August 2017

issue

2

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4 August 2017

page(s)

182-192

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Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors

4 August 2017

cites work

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Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

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Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas

8 July 2018

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BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.

8 July 2018

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Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

8 July 2018

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RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology

8 July 2018

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MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas

8 July 2018

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8 July 2018

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Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas

8 July 2018

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Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

8 July 2018

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Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

8 July 2018

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Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene

8 July 2018

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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

8 July 2018

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High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas.

8 July 2018

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BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

8 July 2018

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8 July 2018

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8 July 2018

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B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms

8 July 2018

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Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

8 July 2018

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Mutations of the BRAF gene in human cancer

8 July 2018

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8 July 2018

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Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma

8 July 2018

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Outcome analysis of childhood pilocytic astrocytomas: a retrospective study of 148 cases at a single institution

21 January 2018

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BRAF alterations in pediatric low grade gliomas and mixed neuronal-glial tumors

21 January 2018

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Clinical utilization of high-resolution single nucleotide polymorphism based oligonucleotide arrays in diagnostic studies of pediatric patients with solid tumors

21 January 2018

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Outcome analysis of childhood low-grade astrocytomas

21 January 2018

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Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

21 January 2018

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BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma.

21 January 2018

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Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas

21 January 2018

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Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.

21 January 2018

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Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

21 January 2018

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RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort.

21 January 2018

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RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BPA.12167

1 reference

4 August 2017

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4 August 2017

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