Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila (Q34808737)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21486956 AND SRC:MED&resulttype=core&format=json

28 January 2020

title

Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21486956 AND SRC:MED&resulttype=core&format=json

Adenomatous polyposis coli 2 Dmel_CG6193

28 January 2020

main subject

Drosophila

0 references

1 reference

GOA release 2020-03-11

author

Sandra G Zimmerman

3

1 reference

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28 January 2020

author name string

Meng-Ning Zhou

1

1 reference

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28 January 2020

Ezgi Kunttas-Tatli

2

1 reference

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28 January 2020

Fangyuan Zhouzheng

4

1 reference

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28 January 2020

Brooke M McCartney

5

1 reference

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28 January 2020

language of work or name

English

0 references

publication date

12 April 2011

1 reference

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28 January 2020

published in

Journal of Cell Science

1 reference

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28 January 2020

volume

124

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28 January 2020

issue

Pt 9

1 reference

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28 January 2020

page(s)

1589-1600

1 reference

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describes a project that uses

28 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3078822/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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APC is a component of an organizing template for cortical microtubule networks

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Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

8 July 2018

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Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

8 July 2018

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The Wnt signaling pathway in development and disease

8 July 2018

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Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function

8 July 2018

1 reference

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Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

8 July 2018

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EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

8 July 2018

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Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC

8 July 2018

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Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex

8 July 2018

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Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells

8 July 2018

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A role for the Adenomatous Polyposis Coli protein in chromosome segregation

8 July 2018

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Asef, a link between the tumor suppressor APC and G-protein signaling

8 July 2018

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A screen for mutations that suppress the phenotype of Drosophila armadillo, the beta-catenin homolog.

8 July 2018

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Structural basis of the Axin-adenomatous polyposis coli interaction

8 July 2018

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Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Association of the APC tumor suppressor protein with catenins

8 July 2018

1 reference

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Association of the APC gene product with beta-catenin

8 July 2018

1 reference

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Dimer formation by an N-terminal coiled coil in the APC protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

The APC gene product associates with microtubules in vivo and promotes their assembly in vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Wild-type but not mutant APC associates with the microtubule cytoskeleton.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

The cytoskeleton and morphogenesis of the early Drosophila embryo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

APC binds to the novel protein EB1

8 July 2018

1 reference

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Cell lines derived from late embryonic stages of Drosophila melanogaster

8 July 2018

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Identification of deletion mutations and three new genes at the familial polyposis locus

8 July 2018

1 reference

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Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

8 July 2018

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Identification of FAP locus genes from chromosome 5q21

8 July 2018

1 reference

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Identification and characterization of the familial adenomatous polyposis coli gene

8 July 2018

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A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila

8 July 2018

1 reference

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Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

The APC tumour suppressor has a nuclear export function.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

A new Drosophila APC homologue associated with adhesive zones of epithelial cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Association between wild type and mutant APC gene products.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078822

Mutations in the APC tumour suppressor gene cause chromosomal instability

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21486956

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.073916

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21486956 AND SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21486956 AND SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

21486956

1 reference