A reevaluation of integrins as regulators of angiogenesis (Q34805783)

4 August 2017

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title

A reevaluation of integrins as regulators of angiogenesis (English)

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4 August 2017

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Richard O Hynes

1

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4 August 2017

language of work or name

English

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publication date

1 September 2002

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4 August 2017

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4 August 2017

volume

8

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4 August 2017

issue

9

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4 August 2017

page(s)

918-921

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Integrins: versatility, modulation, and signaling in cell adhesion

4 August 2017

cites work

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21 January 2018

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Function and interactions of integrins

21 January 2018

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Integrins in vascular development.

21 January 2018

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The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

21 January 2018

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Adhesion events in angiogenesis.

21 January 2018

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 January 2018

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

21 January 2018

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Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

21 January 2018

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Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases

21 January 2018

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Consequences of lack of beta 1 integrin gene expression in mice

21 January 2018

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Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

21 January 2018

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Beta 1 integrin is essential for teratoma growth and angiogenesis

21 January 2018

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Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

21 January 2018

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Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice

21 January 2018

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Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin

21 January 2018

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Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins

21 January 2018

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Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins

21 January 2018

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Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

21 January 2018

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Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin

21 January 2018

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Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins

21 January 2018

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Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

21 January 2018

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Sensing the environment: a historical perspective on integrin signal transduction

21 January 2018

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Trans-dominant inhibition of integrin function.

21 January 2018

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The functions of thrombospondin-1 and-2.

21 January 2018

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Thrombospondins: multifunctional regulators of cell interactions

21 January 2018

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Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor

21 January 2018

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 January 2018

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New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.

21 January 2018

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Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties

21 January 2018

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Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells

21 January 2018

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Interaction of endostatin with integrins implicated in angiogenesis

21 January 2018

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Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

21 January 2018

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Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

21 January 2018

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Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity

21 January 2018

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A molecular mechanism of integrin crosstalk: alphavbeta3 suppression of calcium/calmodulin-dependent protein kinase II regulates alpha5beta1 function

21 January 2018

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The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin

21 January 2018

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The inhibition of vascular smooth muscle cell migration by peptide and antibody antagonists of the alphavbeta3 integrin complex is reversed by activated calcium/calmodulin- dependent protein kinase II

21 January 2018

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Regulation of integrin alpha vbeta 3-mediated endothelial cell migration and angiogenesis by integrin alpha5beta1 and protein kinase A.

21 January 2018

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Networks and crosstalk: integrin signalling spreads.

21 January 2018

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The extracellular matrix as a cell survival factor

21 January 2018

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21 January 2018

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RGD peptides induce apoptosis by direct caspase-3 activation.

21 January 2018

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Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

21 January 2018

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Intrinsic activating properties of GP IIb/IIIa blockers

21 January 2018

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Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

21 January 2018

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7 January 2021

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization

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7 January 2021

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

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7 January 2021

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

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7 January 2021

Interaction of endostatin with integrins implicated in angiogenesis

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7 January 2021

Glycoprotein IIb/IIIa antagonists induce apoptosis in rat cardiomyocytes by caspase-3 activation

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7 January 2021

Integrin-mediated death: an explanation of the integrin-knockout phenotype?

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7 January 2021

Identifiers

DOI

10.1038/NM0902-918

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release_ebbg45cwrzdorku4ddz5rinkhq

4 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ebbg45cwrzdorku4ddz5rinkhq

24 November 2022

mapped directly with Wikidata item

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