Self-complementary AAV vectors; advances and applications (Q34804660)

4 August 2017

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title

Self-complementary AAV vectors; advances and applications (English)

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4 August 2017

Douglas M McCarty

1

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4 August 2017

publication date

5 August 2008

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4 August 2017

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4 August 2017

volume

16

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4 August 2017

issue

10

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4 August 2017

page(s)

1648-1656

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Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

4 August 2017

cites work

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7 January 2021

Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

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7 January 2021

Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction

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7 January 2021

Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors

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7 January 2021

Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction

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7 January 2021

Purification of host cell enzymes involved in adeno-associated virus DNA replication

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7 January 2021

Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins

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7 January 2021

Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo

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7 January 2021

Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison

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7 January 2021

Efficient mouse airway transduction following recombination between AAV vectors carrying parts of a larger gene.

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7 January 2021

Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction

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7 January 2021

Adeno-associated virus of a single-polarity DNA genome is capable of transduction in vivo

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7 January 2021

Effects of gamma irradiation on the transduction of dividing and nondividing cells in brain and muscle of rats by adeno-associated virus vectors

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7 January 2021

Adeno-associated virus 2-mediated gene transfer: role of a cellular serine/threonine protein phosphatase in augmenting transduction efficiency

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7 January 2021

Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo

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7 January 2021

Looking into the safety of AAV vectors

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7 January 2021

Adeno-associated virus vectors integrate at chromosome breakage sites

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7 January 2021

AAV vectors, insertional mutagenesis, and cancer

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7 January 2021

Transduction of hepatocellular carcinoma (HCC) using recombinant adeno-associated virus (rAAV): in vitro and in vivo effects of genotoxic agents

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7 January 2021

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

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7 January 2021

AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.

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7 January 2021

Single-stranded DNA-protein interactions in canine parvovirus.

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7 January 2021

DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids

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7 January 2021

The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity

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7 January 2021

Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

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7 January 2021

Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo

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7 January 2021

Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity.

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7 January 2021

Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector

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7 January 2021

Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose

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7 January 2021

Quantitative analysis of the packaging capacity of recombinant adeno-associated virus

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7 January 2021

The packaging capacity of adeno-associated virus (AAV) and the potential for wild-type-plus AAV gene therapy vectors

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7 January 2021

Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice.

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7 January 2021

Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps

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7 January 2021

Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction

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7 January 2021

Infectious Clones and Vectors Derived from Adeno-Associated Virus (AAV) Serotypes Other Than AAV Type 2

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7 January 2021

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

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7 January 2021

High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes

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7 January 2021

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

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7 January 2021

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

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7 January 2021

Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia.

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7 January 2021

Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency

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7 January 2021

Genomic stability of self-complementary adeno-associated virus 2 during early stages of transduction in mouse muscle in vivo

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7 January 2021

Rapid, widespread transduction of the murine myocardium using self-complementary Adeno-associated virus

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7 January 2021

Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.

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7 January 2021

Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart

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7 January 2021

Adeno-associated virus (AAV) vectors in the CNS.

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7 January 2021

Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain

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7 January 2021

Significantly increased lifespan and improved behavioral performances by rAAV gene delivery in adult mucopolysaccharidosis IIIB mice

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7 January 2021

Neonatal intraperitoneal or intravenous injections of recombinant adeno-associated virus type 8 transduce dorsal root ganglia and lower motor neurons

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7 January 2021

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model

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7 January 2021

Intraneural colchicine inhibition of adenoviral and adeno-associated viral vector remote spinal cord gene delivery

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7 January 2021

Efficient retrograde neuronal transduction utilizing self-complementary AAV1

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7 January 2021

Adeno-associated viral vectors and the retina

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7 January 2021

AAV-mediated gene therapy for retinal disorders: from mouse to man.

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7 January 2021

Versatility of AAV vectors for retinal gene transfer

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7 January 2021

Effect of gene therapy on visual function in Leber's congenital amaurosis

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7 January 2021

Safety and efficacy of gene transfer for Leber's congenital amaurosis

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7 January 2021

Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.

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7 January 2021

Ocular gene transfer with self-complementary AAV vectors

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7 January 2021

Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8.

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7 January 2021

Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells

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7 January 2021

RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism

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7 January 2021

Role of viral vectors and virion shells in cellular gene expression

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7 January 2021

Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2.

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7 January 2021

Targeting gene expression to cones with human cone opsin promoters in recombinant AAV.

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7 January 2021

Adeno-associated virus type 2-mediated transduction of murine hematopoietic cells with long-term repopulating ability and sustained expression of a human globin gene in vivo

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7 January 2021

Adeno-associated virus type 2-mediated transduction in primary human bone marrow-derived CD34 hematopoietic progenitor cells: donor variation and correlation of transgene expression with cellular differentiation

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7 January 2021

Hematopoietic stem cell transduction by recombinant adeno-associated virus vectors: problems and solutions

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7 January 2021

Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5.

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7 January 2021

Stable integration of recombinant adeno-associated virus vector genomes after transduction of murine hematopoietic stem cells.

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7 January 2021

Recombinant self-complementary adeno-associated virus serotype vector-mediated hematopoietic stem cell transduction and lineage-restricted, long-term transgene expression in a murine serial bone marrow transplantation model.

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7 January 2021

Integration of adeno-associated virus (AAV) and recombinant AAV vectors

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7 January 2021

AAV serotype 2 vectors preferentially integrate into active genes in mice

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7 January 2021

AAV loves an active genome

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7 January 2021

Enhanced transduction of mouse bone marrow-derived dendritic cells by repetitive infection with self-complementary adeno-associated virus 6 combined with immunostimulatory ligands

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7 January 2021

Major subsets of human dendritic cells are efficiently transduced by self-complementary adeno-associated virus vectors 1 and 2.

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7 January 2021

Adeno-associated virus mediated gene transfer into lung cancer cells promoting CD40 ligand-based immunotherapy

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7 January 2021

Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia

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7 January 2021

Enhancement of gene transfer with recombinant adeno-associated virus (rAAV) vectors into primary B-cell chronic lymphocytic leukemia cells by CpG-oligodeoxynucleotides

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7 January 2021

Host cell DNA repair pathways in adeno-associated viral genome processing

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7 January 2021

Effects of adeno-associated virus DNA hairpin structure on recombination

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7 January 2021

Identifiers

DOI

10.1038/MT.2008.171

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4 August 2017

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