Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress (Q34801719)

4 August 2017

title

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress (English)

1 reference

4 August 2017

main subject

endoplasmic reticulum

0 references

author name string

Irina M Bochkis

1

1 reference

4 August 2017

Nir E Rubins

2

1 reference

4 August 2017

Peter White

3

1 reference

4 August 2017

Emma E Furth

4

1 reference

4 August 2017

Joshua R Friedman

5

1 reference

4 August 2017

Klaus H Kaestner

6

1 reference

4 August 2017

language of work or name

English

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publication date

27 July 2008

1 reference

4 August 2017

1 reference

4 August 2017

volume

14

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4 August 2017

issue

8

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4 August 2017

page(s)

828-836

1 reference

Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.

4 August 2017

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

8 July 2018

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8 July 2018

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

8 July 2018

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8 July 2018

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Elevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis

8 July 2018

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8 July 2018

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Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte

8 July 2018

1 reference

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Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate

8 July 2018

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The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

8 July 2018

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Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm.

8 July 2018

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8 July 2018

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8 July 2018

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Glutathione as a primary osmotic driving force in hepatic bile formation

8 July 2018

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8 July 2018

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21 January 2018

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21 January 2018

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26 October 2018

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Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

26 October 2018

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Foxa2 integrates the transcriptional response of the hepatocyte to fasting

26 October 2018

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Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver

26 October 2018

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BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis

26 October 2018

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Hepatocyte Nuclear Factor 4α Is a Central Regulator of Bile Acid Conjugation

26 October 2018

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Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

26 October 2018

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26 October 2018

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Redundant pathways for negative feedback regulation of bile acid production

26 October 2018

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26 October 2018

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Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis

26 October 2018

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The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660816

12 December 2020

inferred from PubMed ID database lookup

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18660816

12 December 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18660816

12 December 2020

inferred from PubMed ID database lookup

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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7 January 2021

inferred from DOI database lookup

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7 January 2021

inferred from DOI database lookup

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.1853

1 reference

4 August 2017

1 reference

4 August 2017

1 reference