Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation (Q34796730)

4 August 2017

title

Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation (English)

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4 August 2017

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Brendan A Hilliard

1

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4 August 2017

Nicola Mason

2

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4 August 2017

Lingyun Xu

3

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4 August 2017

Jing Sun

4

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4 August 2017

Salah-Eddine Lamhamedi-Cherradi

5

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4 August 2017

Hsiou-Chi Liou

6

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4 August 2017

Christopher Hunter

7

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4 August 2017

Youhai H Chen

8

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4 August 2017

language of work or name

English

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publication date

1 September 2002

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Journal of Clinical Investigation

4 August 2017

published in

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4 August 2017

volume

110

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4 August 2017

issue

6

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4 August 2017

page(s)

843-850

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c-Rel regulates interleukin 12 p70 expression in CD8( ) dendritic cells by specifically inducing p35 gene transcription.

4 August 2017

cites work

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8 July 2018

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Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

8 July 2018

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Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis

8 July 2018

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A novel transcription factor, T-bet, directs Th1 lineage commitment

8 July 2018

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

8 July 2018

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Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha

8 July 2018

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Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

8 July 2018

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Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

8 July 2018

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In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock

8 July 2018

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Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

8 July 2018

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NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses

8 July 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

8 July 2018

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RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis

8 July 2018

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Role of cytokines in development of Th1 and Th2 cells

8 July 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

8 July 2018

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T cell activation pathways: B7, LFA-3, and ICAM-1 shape unique T cell profiles.

8 July 2018

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The expanding universe of T-cell subsets: Th1, Th2 and more.

8 July 2018

1 reference

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Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor

8 July 2018

1 reference

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NF-kappa B-like factors in the murine brain. Developmentally-regulated and tissue-specific expression

8 July 2018

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Constitutive NF-kappa B activity in neurons

8 July 2018

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Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

8 July 2018

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

8 July 2018

1 reference

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

8 July 2018

1 reference

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MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by gamma-interferon

8 July 2018

1 reference

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Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151124

The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain

8 July 2018

1 reference

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The murine c-rel proto-oncogene encodes two mRNAs the expression of which is modulated by lymphoid stimuli.

8 July 2018

1 reference

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Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

8 July 2018

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Experimental autoimmune encephalomyelitis in NF-kappa B-deficient mice:roles of NF-kappa B in the activation and differentiation of autoreactive T cells.

26 October 2018

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c-Rel is essential for B lymphocyte survival and cell cycle progression

26 October 2018

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Chronic Inflammation and Susceptibility to Bacterial Infections in Mice Lacking the Polypeptide (p)105 Precursor (NF-κB1) but Expressing p50

26 October 2018

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

26 October 2018

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26 October 2018

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Transcription factor NF-kappa B is activated in microglia during experimental autoimmune encephalomyelitis

9 December 2018

1 reference

12 December 2020

A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation

1 reference

12 December 2020

Murine c-rel transcription is rapidly induced in T-cells and fibroblasts by mitogenic agents and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

1 reference

12 December 2020

c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI0215254

1 reference

4 August 2017

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4 August 2017

1 reference