The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes (Q34790844)

4 August 2017

title

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes (English)

1 reference

4 August 2017

Laurence Heidet

3

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Ralph Witzgall

object named as

Ralph Witzgall

8

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Corinne Antignac

object named as

Corinne Antignac

7

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author name string

Claudia Rohr

1

1 reference

4 August 2017

Jürgen Prestel

2

1 reference

4 August 2017

Hiltraud Hosser

4

1 reference

4 August 2017

Wilhelm Kriz

5

1 reference

4 August 2017

Randy L Johnson

6

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4 August 2017

language of work or name

English

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publication date

1 April 2002

1 reference

Journal of Clinical Investigation

4 August 2017

published in

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4 August 2017

volume

109

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4 August 2017

issue

8

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4 August 2017

page(s)

1073-1082

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Novel mutations in NPHS2 detected in both familial and sporadic steroid-resistant nephrotic syndrome

4 August 2017

cites work

1 reference

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Podocin localizes in the kidney to the slit diaphragm area

8 July 2018

1 reference

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CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain

8 July 2018

1 reference

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Prevalence, genetics, and clinical features of patients carrying podocin mutations in steroid-resistant nonfamilial focal segmental glomerulosclerosis.

8 July 2018

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Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin

8 July 2018

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Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation

8 July 2018

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The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

8 July 2018

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8 July 2018

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In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2

8 July 2018

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Glomerular expression of type IV collagen chains in normal and X-linked Alport syndrome kidneys

8 July 2018

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LMX1B transactivation and expression in nail-patella syndrome

8 July 2018

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract

8 July 2018

1 reference

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Glomerular expression of dystroglycans is reduced in minimal change nephrosis but not in focal segmental glomerulosclerosis.

8 July 2018

1 reference

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LMX1B, a LIM homeodomain class transcription factor, is necessary for normal development of multiple tissues in the anterior segment of the murine eye

8 July 2018

1 reference

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The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis

8 July 2018

1 reference

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Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Nephrin localizes to the slit pore of the glomerular epithelial cell

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

The forkhead/winged-helix gene, Mf1, is necessary for the normal development of the cornea and formation of the anterior chamber in the mouse eye

8 July 2018

1 reference

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Nephrin is specifically located at the slit diaphragm of glomerular podocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

8 July 2018

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A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome

8 July 2018

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Mutation analysis of LMX1B gene in nail-patella syndrome patients

8 July 2018

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A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

8 July 2018

1 reference

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Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome

8 July 2018

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Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro

8 July 2018

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The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells

8 July 2018

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Identification of a Human LMX1 (LMX1.1)-Related Gene, LMX1.2: Tissue-Specific Expression and Linkage Mapping on Chromosome 9

8 July 2018

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Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis

8 July 2018

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Donor splice-site mutations in WT1 are responsible for Frasier syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Synaptopodin: An Actin-associated Protein in Telencephalic Dendrites and Renal Podocytes

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Vascular endothelial growth factor is an essential molecule for mouse kidney development: glomerulogenesis and nephrogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Efficient DNA transfection of quiescent mammalian cells using poly-L-ornithine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

The candidate Wilms' tumour gene is involved in genitourinary development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Nail-patella syndrome in a spontaneously aborted 18-week fetus: ultrastructural and immunofluorescent study of the kidneys

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

The nephropathy of the nail-patella syndrome. Clinicopathologic analysis of 11 kindred.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Congenital nephrotic syndrome in mice lacking CD2-associated protein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150943

Mutations in NPHS2 encoding podocin are a prevalent cause of steroid-resistant nephrotic syndrome among Israeli-Arab children

26 October 2018

1 reference

12 December 2020

An electron microscopic study of thrombin-induced disseminated intravascular coagulation

1 reference

12 December 2020

Ultrastructure of the Kidney in the Nephropathy of the Nail-Patella Syndrome

1 reference

12 December 2020

The glomerular basement membrane in the nail-patella syndrome

1 reference

12 December 2020

Hereditary osteo-onycho-renal dysplasia with excess urinary pyridinoline cross-links and abnormal kidney collagen cross-linking

1 reference

12 December 2020

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1 reference

12 December 2020

VEGF is required for growth and survival in neonatal mice

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12 December 2020

Alport syndrome and thin glomerular basement membrane disease

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12 December 2020

Congenital nephrotic syndrome (NPHS1): features resulting from different mutations in Finnish patients

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12 December 2020

Identifiers

DOI

10.1172/JCI0213961

1 reference

4 August 2017

1 reference

4 August 2017

1 reference