Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease (Q34788330)

4 August 2017

title

Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease (English)

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4 August 2017

7

Bruce R Blazar

1 reference

4 August 2017

Koji Tamada

1

1 reference

4 August 2017

Hideto Tamura

2

1 reference

4 August 2017

Dallas Flies

3

1 reference

4 August 2017

Yang-Xin Fu

4

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4 August 2017

Esteban Celis

5

1 reference

4 August 2017

Larry R Pease

6

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4 August 2017

Lieping Chen

8

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4 August 2017

language of work or name

English

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publication date

1 February 2002

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Journal of Clinical Investigation

4 August 2017

published in

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4 August 2017

volume

109

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4 August 2017

issue

4

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4 August 2017

page(s)

549-557

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CD4( )CD25( ) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

4 August 2017

cites work

1 reference

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A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis

8 July 2018

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8 July 2018

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CD4( ) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses

8 July 2018

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8 July 2018

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8 July 2018

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Involvement of CD40 ligand-CD40 and CTLA4-B7 pathways in murine acute graft-versus-host disease induced by allogeneic T cells lacking CD28.

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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T cell receptor antagonist peptides induce positive selection

8 July 2018

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Lymphocyte life-span and memory

8 July 2018

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8 July 2018

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Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway

8 July 2018

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Peripheral T cell tolerance

8 July 2018

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A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

8 July 2018

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Lethal graft-versus-host disease in mice directed to multiple minor histocompatibility antigens: features of CD8 and CD4 T cell responses

8 July 2018

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8 July 2018

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Opposing roles of CD28:B7 and CTLA-4:B7 pathways in regulating in vivo alloresponses in murine recipients of MHC disparate T cells

8 July 2018

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Transplantation of anergic histoincompatible bone marrow allografts

26 October 2018

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26 October 2018

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A conditioned dendritic cell can be a temporal bridge between a CD4 T-helper and a T-killer cell

26 October 2018

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Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

26 October 2018

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In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice

26 October 2018

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Visualization, fate, and pathogenicity of antigen-specific CD8 T cells in the graft-versus-host reaction

26 October 2018

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12 December 2020

LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response

1 reference

12 December 2020

Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients

1 reference

12 December 2020

Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

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12 December 2020

Infusion of anti-B7.1 (CD80) and anti-B7.2 (CD86) monoclonal antibodies inhibits murine graft-versus-host disease lethality in part via direct effects on CD4 and CD8 T cells

1 reference

12 December 2020

Blockade of CD40 ligand-CD40 interaction impairs CD4 T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation

1 reference

12 December 2020

Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells

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12 December 2020

Turning off follicular dendritic cells

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12 December 2020

Cutting edge: sustained expansion of CD8 T cells requires CD154 expression by Th cells in acute graft versus host disease

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12 December 2020

The fate of donor T-cell receptor transgenic T cells with known host antigen specificity in a graft-versus-host disease model

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12 December 2020

Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation

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12 December 2020

Identifiers

DOI

10.1172/JCI0213604

1 reference

4 August 2017

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4 August 2017

1 reference