Synthesis and preliminary evaluation of a new (99m)tc labeled substance p analogue as a potential tumor imaging agent (Q34777749)

25561916

4 August 2017

title

Synthesis and preliminary evaluation of a new (99m)tc labeled substance p analogue as a potential tumor imaging agent (English)

1 reference

ethylenediamine-N,N'-diacetic acid

4 August 2017

0 references

1 reference

ChEBI release 2020-05-28

3

1 reference

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2 June 2020

author name string

Saeed Mozaffari

1

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2 June 2020

Mostafa Erfani

2

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2 June 2020

Fariba Johari Daha

4

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2 June 2020

Farzad Kobarfard

5

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2 June 2020

Saeed Balalaie

6

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2 June 2020

Babak Fallahi

7

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2 June 2020

publication date

1 January 2015

1 reference

25561916

Iranian journal of pharmaceutical research

4 August 2017

published in

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2 June 2020

volume

14

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2 June 2020

issue

1

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2 June 2020

page(s)

97-110

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EGF receptor targeted tumor imaging with biotin-PEG-EGF linked to (99m)Tc-HYNIC labeled avidin and streptavidin

2 June 2020

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Substance P Induces Rapid and Transient Membrane Blebbing in U373MG Cells in a p21-Activated Kinase-Dependent Manner

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The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines

7 July 2018

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7 July 2018

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Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance p.

7 July 2018

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The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines

7 July 2018

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7 July 2018

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Design, synthesis and preclinical evaluation of radiolabeled peptides for diagnosis and therapy

7 July 2018

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Peptide-based radiopharmaceuticals: future tools for diagnostic imaging of cancers and other diseases

7 July 2018

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Tachykinins and tachykinin receptors: a growing family

7 July 2018

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A 99mTc(I)-postlabeled high affinity bombesin analogue as a potential tumor imaging agent

7 July 2018

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7 July 2018

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Molecular characterization of the substance P*neurokinin-1 receptor complex: development of an experimentally based model.

7 July 2018

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Further definition of the substance P (SP)/neurokinin-1 receptor complex. MET-174 is the site of photoinsertion p-benzoylphenylalanine4 SP.

7 July 2018

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The role of tachykinins via NK1 receptors in progression of human gliomas.

7 July 2018

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Central and peripheral expression of neurokinin-1 and neurokinin-3 receptor and substance P-encoding messenger RNAs: peripheral regulation during formalin-induced inflammation and lack of neurokinin receptor expression in primary afferent sensory ne

7 July 2018

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Internalization of radiolabelled [DTPA0]octreotide and [DOTA0,Tyr3]octreotide: peptides for somatostatin receptor-targeted scintigraphy and radionuclide therapy

7 July 2018

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7 July 2018

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7 July 2018

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Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor

7 July 2018

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A study of [d-Pro2, d-Phe7, d-Trp9]-substance P and [d-Trp7,9]-substance P as tachykinin partial agonists in the rat colon

7 July 2018

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Synthesis of peptides by the solid-phase method. 7. Substance P and analogs

7 July 2018

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Active Uptake of Substance P Carboxy-Terminal Heptapeptide (5?11) into Rat Brain and Rabbit Spinal Cord Slices

7 July 2018

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Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats.

7 July 2018

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Molecular cloning, structural characterization and functional expression of the human substance P receptor

7 July 2018

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125I-BH[Sar9, Met(O2)11]-SP, a new selective ligand for the NK-1 receptor in the central nervous system

7 July 2018

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Potent and highly selective neurokinin antagonists

7 July 2018

1 reference

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Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial

7 July 2018

1 reference

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How do HYNIC-conjugated peptides bind technetium? Insights from LC-MS and stability studies.

26 October 2018

1 reference

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Individual voxelwise dosimetry of targeted 90Y-labelled substance P radiotherapy for malignant gliomas

26 October 2018

1 reference

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Optimization of the preparation of 99mTc-labeled Hynic-derivatized Annexin V for human use

26 October 2018

1 reference

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Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain

26 October 2018

1 reference

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In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands

26 October 2018

1 reference

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Preparation of 99mTc labeled substance P (SP).

26 October 2018

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Effects of coligand variation on the in vivo characteristics of Tc-99m-labeled interleukin-8 in detection of infection

26 October 2018

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Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide

26 October 2018

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(99m)Tc-HYNIC-derivatized ternary ligand complexes for (99m)Tc-labeled polypeptides with low in vivo protein binding

26 October 2018

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Confirmation of hydrazone formation in HYNIC-peptide conjugate preparation, and its hydrolysis during labeling with (99m)Tc

26 October 2018

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12 December 2020

Preclinical evaluation of [99mTc/EDDA/tricine/HYNIC0, 1-Nal3, Thr8]-octreotide as a new analogue in the detection of somatostatin-receptor-positive tumors

1 reference

12 December 2020

Detection of somatostatin receptor-positive tumours using the new 99mTc-tricine-HYNIC-d-Phel-Tyr3-octreotide: first results in patients and comparison with 111In-DTPA-D-Phe1-octreotide

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12 December 2020

Tachykinin regulation of airway smooth muscle cell proliferation

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12 December 2020

High Affinity Binding of [3H]Propionyl-[Met(O2)11]Substance P(7–11), a Tritiated Septide-Like Peptide, in Chinese Hamster Ovary Cells Expressing Human Neurokinin-1 Receptors and in Rat Submandibular Glands

1 reference

12 December 2020

Substance-P receptors in human primary neoplasms: tumoral and vascular localization

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12 December 2020

Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor

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12 December 2020

Radiolabeling of bombesin-like peptide with 99mTc: 99mTc-litorin and biodistribution in rats

1 reference

12 December 2020

Chemoselective hydrazone formation between HYNIC-functionalized peptides and 18F-fluorinated aldehydes

1 reference

12 December 2020

Biological activity of C-terminal partial sequences of substance P

1 reference

12 December 2020

Structure-activity studies on the C-terminal hexapeptide of substance P with modifications at the glutaminyl and methioninyl residues

1 reference

12 December 2020

Effect of "co-ligand" on the biodistribution of 99mTc-labeled hydrazino nicotinic acid derivatized chemotactic peptides

1 reference

12 December 2020

Intracellular metabolic fate of radioactivity after injection of technetium-99m-labeled hydrazino nicotinamide derivatized proteins

1 reference

12 December 2020

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2 June 2020

25561916

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