The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1. (Q34769739)

4 August 2017

title

The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1. (English)

1 reference

4 August 2017

Angela M Gronenborn

8

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author name string

Jinwoo Ahn

1

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4 August 2017

Zach Novince

2

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4 August 2017

Jason Concel

3

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4 August 2017

Chang-Hyeock Byeon

4

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4 August 2017

Alexander M Makhov

5

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4 August 2017

In-Ja L Byeon

6

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4 August 2017

Peijun Zhang

7

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4 August 2017

language of work or name

English

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publication date

31 January 2011

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4 August 2017

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4 August 2017

volume

50

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4 August 2017

issue

8

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4 August 2017

page(s)

1359-1367

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HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation

4 August 2017

cites work

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7 July 2018

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Multitasking with ubiquitin through multivalent interactions

7 July 2018

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HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest

7 July 2018

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CRL4s: the CUL4-RING E3 ubiquitin ligases

7 July 2018

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7 July 2018

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Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

7 July 2018

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7 July 2018

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7 July 2018

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Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation.

7 July 2018

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Cullin-RING ubiquitin ligases: global regulation and activation cycles

7 July 2018

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HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

7 July 2018

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DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

7 July 2018

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The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

7 July 2018

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Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

7 July 2018

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DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

7 July 2018

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Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination

7 July 2018

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HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

7 July 2018

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Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases

7 July 2018

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HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

7 July 2018

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Fbw7/hCDC4 dimerization regulates its substrate interactions

7 July 2018

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Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy

7 July 2018

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Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization

7 July 2018

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DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases

7 July 2018

1 reference

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CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

7 July 2018

1 reference

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Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

7 July 2018

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A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

7 July 2018

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The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

7 July 2018

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The dimerization mechanism of LIS1 and its implication for proteins containing the LisH motif

7 July 2018

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Novel functional features of the Lis-H domain: role in protein dimerization, half-life and cellular localization.

7 July 2018

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Function and regulation of cullin-RING ubiquitin ligases

7 July 2018

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Polyubiquitin chains: polymeric protein signals

7 July 2018

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The structure of the N-terminal domain of the product of the lissencephaly gene Lis1 and its functional implications

7 July 2018

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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

7 July 2018

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A new sequence motif linking lissencephaly, Treacher Collins and oral-facial-digital type 1 syndromes, microtubule dynamics and cell migration

7 July 2018

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Mechanisms underlying ubiquitination

7 July 2018

1 reference

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7 July 2018

1 reference

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Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination

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Identifiers

DOI

10.1021/BI101749S

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4 August 2017

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4 August 2017

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