A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels (Q34764487)

4 August 2017

title

A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels (English)

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4 August 2017

10

Guido Marcucci

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4 August 2017

Ping Chen

1

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4 August 2017

Zhongfa Liu

2

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4 August 2017

Shujun Liu

3

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4 August 2017

Zhiliang Xie

4

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4 August 2017

Josephine Aimiuwu

5

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4 August 2017

Jiuxia Pang

6

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4 August 2017

Rebecca Klisovic

7

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4 August 2017

William Blum

8

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4 August 2017

Michael R Grever

9

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4 August 2017

Kenneth K Chan

11

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4 August 2017

publication date

17 March 2009

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4 August 2017

published in

Pharmaceutical Research

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4 August 2017

volume

26

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4 August 2017

issue

6

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4 August 2017

page(s)

1504-1515

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Phase I study of GTI-2040, an antisense to ribonucleotide reductase, in combination with high-dose cytarabine in patients with acute myeloid leukemia

4 August 2017

cites work

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Ribonucleotide reductase inhibitors and future drug design

7 July 2018

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Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome

7 July 2018

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Analysis of intracellular nucleoside triphosphate levels in normal and tumor cell lines by high-performance liquid chromatography

7 July 2018

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Interference of gemcitabine triphosphate with the measurements of deoxynucleotides using an optimized DNA polymerase elongation assay.

7 July 2018

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Analysis of an adenine nucleotide-containing metabolite of clodronate using ion pair high-performance liquid chromatography-electrospray ionisation mass spectrometry

7 July 2018

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Simultaneous determination of pyrimidine or purine deoxyribonucleoside triphosphates using a polymerase assay

7 July 2018

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Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography–electrospray mass spectrometry

7 July 2018

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An ion-pairing high-performance liquid chromatographic method for the direct simultaneous determination of nucleotides, deoxynucleotides, nicotinic coenzymes, oxypurines, nucleosides, and bases in perchloric acid cell extracts.

7 July 2018

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Kinetic mechanism of mitochondrial adenosine triphosphatase. Inhibition by azide and activation by sulphite

7 July 2018

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Effect of methylamine on periodate-oxidized adenosine 5'-phosphate.

7 July 2018

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Comparison of sample preparation methods for the high-performance liquid chromatographic analysis of cell culture extracts for triphosphate ribonucleosides and deoxyribonucleosides.

7 July 2018

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The quantitative determination of 2'-deoxycytidine-5'-triphosphate in cell extracts by radioimmunoassay

7 July 2018

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Quantitation of deoxyribonucleoside 5'-triphosphates by a sequential boronate and anion-exchange high-pressure liquid chromatographic procedure

7 July 2018

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A study of matrix effects on an LC/MS/MS assay for olanzapine and desmethyl olanzapine

7 July 2018

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GTI-2040, an antisense agent targeting the small subunit component (R2) of human ribonucleotide reductase, shows potent antitumor activity against a variety of tumors.

26 October 2018

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Liquid chromatography–tandem mass spectrometry assays for intracellular deoxyribonucleotide triphosphate competitors of nucleoside antiretrovirals

26 October 2018

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Development of a direct assay for measuring intracellular AZT triphosphate in humans peripheral blood mononuclear cells

26 October 2018

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A direct determination of thymidine triphosphate concentrations without dephosphorylation in peripheral blood mononuclear cells by LC/MS/MS.

26 October 2018

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Simultaneous determination of Ziagen and its phosphorylated metabolites by ion-pairing high-performance liquid chromatography-tandem mass spectrometry

26 October 2018

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A simplified HPLC method for simultaneously quantifying ribonucleotides and deoxyribonucleotides in cell extracts or frozen tissues

26 October 2018

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Deoxynucleotide pools and DNA synthesis in resting and PHA-stimulated human lymphocytes treated with mutagens

26 October 2018

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12 December 2020

Improved high-performance liquid chromatographic analysis of intracellular deoxyribonucleoside triphosphate levels

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12 December 2020

Comparison of extraction procedures for high-performance liquid chromatographic determination of cellular deoxynucleotides

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12 December 2020

Enzymatic assay for quantification of deoxynucleoside triphosphates in human cells exposed to antiretroviral 2',3'-dideoxynucleosides

1 reference

12 December 2020

Immunoreactive dUMP and TTP pools as an index of thymidylate synthase inhibition; effect of tomudex (ZD1694) and a nonpolyglutamated quinazoline antifolate (CB30900) in L1210 mouse leukaemia cells

1 reference

12 December 2020

Simultaneous determination of deoxyribonucleoside in the presence of ribonucleoside triphosphates in human carcinoma cells by high-performance liquid chromatography

1 reference

12 December 2020

A phase I study of antisense oligonucleotide GTI-2040 given by continuous intravenous infusion in patients with advanced solid tumors

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12 December 2020

A Specific Picomolar Hybridization-Based ELISA Assay for the Determination of Phosphorothioate Oligonucleotides in Plasma and Cellular Matrices

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12 December 2020

A Phase I/II study of GTI-2040 and capecitabine in patients with renal cell carcinoma

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12 December 2020

Positive ion electrospray ionization tandem mass spectrometry coupled to ion-pairing high-performance liquid chromatography with a phosphate buffer for the quantitative analysis of intracellular nucleotides

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12 December 2020

An Enzymatic Method for the Determination of dCTP and dGTP in Picomole Amounts

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12 December 2020

Periodate oxidations of enamines. I. Oxidation of adenosine 5'-monophosphate in the presence of methylamine

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12 December 2020

Periodate oxidation and amino-catalyzed elimination of the terminal nucleoside from adenylate or ribonucleic acid. Products of overoxidation

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12 December 2020

Detection of activities that interfere with the enzymatic assay of deoxyribonucleoside 5'-triphosphates

1 reference

12 December 2020

An improved method for the quantitative determination of deoxyribonucleoside triphosphates in cell extracts

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12 December 2020

Determination of ribonucleoside triphosphates and deoxyribonucleoside triphosphates in Novikoff hepatoma cells by high-performance liquid chromatography

1 reference

12 December 2020

10.1007/S11095-009-9863-9

Identifiers

DOI

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4 August 2017

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4 August 2017

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