The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease (Q34750643)

4 August 2017

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title

The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease (English)

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4 August 2017

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George Perry

5

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Mark Anthony Smith

series ordinal

6

object named as

Mark A Smith

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4 August 2017

2

Craig S Atwood

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4 August 2017

Catherine A. Rottkamp

series ordinal

1

object named as

Catherine A Rottkamp

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4 August 2017

4

Akihiko Nunomura

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4 August 2017

James A Joseph

3

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4 August 2017

publication date

1 July 2002

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4 August 2017

number of pages

9

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inferred from page(s)

published in

Peptides

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4 August 2017

volume

23

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4 August 2017

issue

7

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4 August 2017

page(s)

1333-1341

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Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

4 August 2017

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Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides

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Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells.

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Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

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7 January 2021

Molecular basis of Alzheimer's disease

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APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

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Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils

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Neuronal polo-like kinase in Alzheimer disease indicates cell cycle changes

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A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

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Possible Causes of Alzheimer's Disease: Amyloid Fragments, Free Radicals, and Calcium Homeostasis

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

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Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain

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7 January 2021

Copernicus revisited: amyloid beta in Alzheimer's disease

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7 January 2021

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

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7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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7 January 2021

Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma

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7 January 2021

Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth

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7 January 2021

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

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7 January 2021

In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

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7 January 2021

The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

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7 January 2021

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

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7 January 2021

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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7 January 2021

Amyloid fibril toxicity in Alzheimer's disease and diabetes

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7 January 2021

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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7 January 2021

Physiological levels of beta-amyloid peptide promote PC12 cell proliferation

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7 January 2021

Deposition of amyloid beta protein in non-Alzheimer dementias: evidence for a neuronal origin of parenchymal deposits of beta protein in neurodegenerative disease.

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7 January 2021

Amyloid plaque core protein in Alzheimer disease and Down syndrome

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Degenerative and protective signaling mechanisms in the neurofibrillary pathology of AD.

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Cell cycle markers in the hippocampus in Alzheimer's disease

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Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment

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Oxidative damage is the earliest event in Alzheimer disease

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The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents

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Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells

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beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology

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Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

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Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats

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Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures

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The role of cell cycle-mediated events in Alzheimer's disease

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Mitotic neurons: a dogma succumbs

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Abortive oncogeny and cell cycle-mediated events in Alzheimer disease.

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Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease

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7 January 2021

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

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7 January 2021

Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease

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7 January 2021

Oxidative stress, antioxidants, and Alzheimer disease

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7 January 2021

Redox-active iron mediates amyloid-beta toxicity

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7 January 2021

Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal

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7 January 2021

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

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7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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7 January 2021

Amyloid beta-protein and the genetics of Alzheimer's disease

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Translating cell biology into therapeutic advances in Alzheimer's disease

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7 January 2021

Hypoglycemia enhances the expression of mRNA encoding β-amyloid precursor protein in rat primary cortical astroglial cells

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7 January 2021

Estrogen attenuates over-expression of beta-amyloid precursor protein messager RNA in an animal model of focal ischemia

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7 January 2021

Hypoperfusion induces overexpression of beta-amyloid precursor protein mRNA in a focal ischemic rodent model

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7 January 2021

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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7 January 2021

Effect of substance P and protein kinase inhibitors on beta-amyloid peptide-induced proliferation of cultured brain cells

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7 January 2021

Secretion of the β‐Amyloid Precursor Proteina

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7 January 2021

Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders

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7 January 2021

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

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7 January 2021

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

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7 January 2021

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

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7 January 2021

Arson. Tracking the culprit in Alzheimer's disease

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7 January 2021

ApoE as a prognostic factor for post–traumatic coma

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7 January 2021

Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat

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7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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7 January 2021

Trophic effects of substance P and beta-amyloid peptide on dibutyryl cyclic AMP-differentiated human leukemic (HL-60) cells

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7 January 2021

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

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7 January 2021

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

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7 January 2021

Rapid appearance of beta-amyloid precursor protein immunoreactivity in glial cells following excitotoxic brain injury

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7 January 2021

New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps.

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7 January 2021

Concentrations of amyloid-beta protein in cerebrospinal fluid increase with age in patients free from neurodegenerative disease

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7 January 2021

Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity

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7 January 2021

Mitotic mechanisms in Alzheimer's disease?

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7 January 2021

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain

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7 January 2021

Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation

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7 January 2021

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

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7 January 2021

Beta-amyloid protein promotes neuritic branching in hippocampal cultures

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7 January 2021

Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease

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7 January 2021

Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury

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7 January 2021

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

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7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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7 January 2021

New clues to Alzheimer's disease: unraveling the roles of amyloid and tau.

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7 January 2021

Cytotoxic fragment of amyloid precursor protein accumulates in hippocampus after global forebrain ischemia

1 reference

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7 January 2021

Cell cycle events in neurons. Proliferation or death?

1 reference

https://api.crossref.org/works/10.1016/S0196-9781(02)50069-4

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Activation of oncogenic pathways in degenerating neurons in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016/S0196-9781(02)50069-4

7 January 2021

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016/S0196-9781(02)50069-4

7 January 2021

Neuronal CDK7 in hippocampus is related to aging and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016/S0196-9781(02)50069-4

7 January 2021

Call for Elan to publish Alzheimer's trial details.

1 reference

https://api.crossref.org/works/10.1016/S0196-9781(02)50069-4

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Nerve inflammation halts trial for Alzheimer's drug.

1 reference

https://api.crossref.org/works/10.1016/S0196-9781(02)50069-4

7 January 2021

10.1016/S0196-9781(02)00069-4

Identifiers

DOI

1 reference

4 August 2017

1 reference