Chronic alcohol ingestion increases mortality and organ injury in a murine model of septic peritonitis (Q34743871)

4 August 2017

title

Chronic alcohol ingestion increases mortality and organ injury in a murine model of septic peritonitis (English)

1 reference

4 August 2017

0 references

1 reference

Elise Breed

2

0 references

Elizabeth R. Lusczek

Elizabeth R Lusczek

8

0 references

Michael Koval

Michael Koval

13

0 references

Alton B. Farris

Alton B Farris

11

0 references

Greg J. Beilman

Greg J Beilman

9

0 references

Craig M Coopersmith

15

Craig M Coopersmith

1 reference

4 August 2017

10

Eileen M Burd

1 reference

4 August 2017

1

Benyam P Yoseph

1 reference

4 August 2017

6

Maylene E Wagener

1 reference

4 August 2017

author name string

Christian E Overgaard

3

1 reference

4 August 2017

Christina J Ward

4

1 reference

4 August 2017

Zhe Liang

5

1 reference

4 August 2017

Daniel R Lexcen

7

1 reference

4 August 2017

David M Guidot

12

1 reference

4 August 2017

Mandy L Ford

14

1 reference

4 August 2017

language of work or name

English

0 references

publication date

22 May 2013

1 reference

4 August 2017

1 reference

4 August 2017

volume

8

1 reference

4 August 2017

issue

5

1 reference

4 August 2017

page(s)

e62792

1 reference

Creative Commons Attribution 4.0 International

4 August 2017

copyright license

start time

22 May 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Cecal ligation and puncture-induced murine sepsis does not cause lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Chronic medical conditions and risk of sepsis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

The endogenous bacteria alter gut epithelial apoptosis and decrease mortality following Pseudomonas aeruginosa pneumonia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Investigation of chronic alcohol consumption in rodents via ultra-high-performance liquid chromatography-mass spectrometry based metabolite profiling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Immunosuppression in patients who die of sepsis and multiple organ failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

A dynamic flux in natural killer cell subsets as a function of the duration of alcohol ingestion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Regulation of lymphocyte trafficking by CXC chemokine receptor 3 during septic shock

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

PPARγ Ligands Regulate NADPH Oxidase, eNOS, and Barrier Function in the Lung Following Chronic Alcohol Ingestion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Epidermal Growth Factor Improves SurvivaL and Prevents Intestinal Injury in a Murine Model of Pseudomonas aeruginosa Pneumonia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Inflammatory Response in Multiple Organs in a Mouse Model of Acute Alcohol Intoxication and Burn Injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Alcohol-use disorders in the critically ill patient

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Can we protect the gut in critical illness? The role of growth factors and other novel approaches

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Milk fat globule EGF factor 8 attenuates sepsis-induced apoptosis and organ injury in alcohol-intoxicated rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Inactivation of hepatocyte nuclear factor-4{alpha} mediates alcohol-induced downregulation of intestinal tight junction proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

The role of zinc deficiency in alcohol-induced intestinal barrier dysfunction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Alcohol, burn injury, and the intestine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

The sepsis seesaw: tilting toward immunosuppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Recent trends in acute lung injury mortality: 1996-2005.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Exogenous IL-15 in combination with IL-15R alpha rescues natural killer cells from apoptosis induced by chronic alcohol consumption

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Differential lymphopenia-induced homeostatic proliferation for CD4 and CD8 T cells following septic injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Thymocytes, pre-B cells, and organ changes in a mouse model of chronic ethanol ingestion--absence of subset-specific glucocorticoid-induced immune cell loss

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Review article: bacterial translocation in the critically ill--evidence and methods of prevention

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Prevalence and impact of alcohol and other drug use disorders on sedation and mechanical ventilation: a retrospective study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Alcohol abuse in the critically ill patient

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

GM-CSF receptor expression and signaling is decreased in lungs of ethanol-fed rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Epidemiology of sepsis: race, sex, and chronic alcohol abuse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Incidence and outcomes of acute lung injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Alcohol abuse and acute lung injury: epidemiology and pathophysiology of a recently recognized association

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Epithelial barrier dysfunction: a unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Low concentrations of ethanol induce apoptosis in human intestinal cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Intestinal barrier: An interface between health and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Intestinal epithelial hyperpermeability: update on the pathogenesis of gut mucosal barrier dysfunction in critical illness

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Perioperative morbidity and mortality in chronic alcoholic patients.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Post-injury multiple organ failure: the role of the gut.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Role of the gut in multiple organ failure: bacterial translocation and permeability changes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

High alcohol intake as a risk and prognostic factor for community-acquired pneumonia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

The gut: a central organ after surgical stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Detection of alcohol use disorders in general hospital admissions in the United States

7 July 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Dose-response relation between volume of drinking and alcohol-related diseases in male general hospital inpatients

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Alcohol consumption and the risk of nosocomial infection in general surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Glutathione replacement preserves the functional surfactant phospholipid pool size and decreases sepsis-mediated lung dysfunction in ethanol-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Ethanol intake inhibits growth of the epithelium in the intestine of pregnant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Peroxynitrite inhibits enterocyte proliferation and modulates Src kinase activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Dose-dependent effects of ethanol and E. coli on gut permeability and cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Ethanol and murine interleukin (IL)-12 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

Consequences of alcohol-induced early dysregulation of responses to trauma/hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

A metabonomic approach to early prognostic evaluation of experimental sepsis by (1)H NMR and pattern recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

A metabolomic approach for diagnosis of experimental sepsis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Alcohol drinking as a predictor of intensive care and hospital mortality in general surgery: a prospective study

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Cell proliferation and its evaluation in the colorectal mucosa: effect of ethanol.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661585

Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest*

26 October 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0062792

21 January 2018

1 reference

12 December 2020

Probable alcohol abuse or dependence: a risk factor for intensive-care readmission in patients undergoing elective vascular and thoracic surgical procedures. Mayo Perioperative Outcomes Group

1 reference

12 December 2020

Ethanol Feeding Inhibits Proinflammatory Cytokine Expression from Murine Alveolar Macrophages Ex Vivo

1 reference

12 December 2020

Intensive care unit stay is prolonged in chronic alcoholic men following tumor resection of the upper digestive tract

1 reference

12 December 2020

Increased intestinal permeability is associated with the development of multiple organ dysfunction syndrome in critically ill ICU patients

1 reference

12 December 2020

Effects of chronic ethanol consumption in experimental sepsis

1 reference

12 December 2020

Multiple-organ-failure syndrome

1 reference

12 December 2020

Ethanol ingestion via glutathione depletion impairs alveolar epithelial barrier function in rats

1 reference

12 December 2020

1 reference

12 December 2020

Alcohol modulates alveolar macrophage tumor necrosis factor-alpha, superoxide anion, and nitric oxide secretion in the rat

1 reference

12 December 2020

Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice

1 reference

12 December 2020

Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway

1 reference

12 December 2020

The effects of chronic alcohol abuse on pulmonary glutathione homeostasis

1 reference

12 December 2020

Over-expression of Bcl-2 provides protection in septic mice by a trans effect

1 reference

12 December 2020

The acute respiratory distress syndrome

1 reference

12 December 2020

Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis

1 reference

12 December 2020

Impact of alcohol abuse in the etiology and severity of community-acquired pneumonia

1 reference

12 December 2020

Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0062792

Identifiers

DOI

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference